Gonadotropin-releasing hormone agonist: A new approach to reversible contraception in female deer

Journal of Wildlife Diseases

Volumn 40, Issue 4, 2004, Pages 713-724

  Baker, Dan L ^a   Wild, Margaret A ^b   Connor, Mary M ^c   Ravivarapu, Harish B ^d   Dunn, Richard L ^e   Nett, Terry M ^f  

^a Research Center ^*  (United States)

^b NATIONAL PARK SERVICE   (United States)

^c UTAH STATE UNIVERSITY   (United States)

^d SuperGen Inc   (United States)

^e QLT Inc   (United States)

^f Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Contraception; GnRH agonist; Leuprolide; Luteinizing hormone; Mule deer; Reproductive behavior

Indexed keywords

CERVIDAE; ODOCOILEUS HEMIONUS; UNGULATA;

EID: 13644250905     PISSN: 00903558     EISSN: None     Source Type: Journal    
DOI: 10.7589/0090-3558-40.4.713     Document Type: Article

References (50)

1. Abramowitz, M., and I. A. Stegun. 1968. Handbook of mathematical functions. Dover Publishing, Inc., New York, New York, 343 pp.
2. Anderson, A. E. 1981. Morphological and physiological characteristics. In Mule and black-tailed deer of North America, O. C. Wallmo (ed.). University of Nebraska Press, Lincoln, Nebraska, pp. 27-97.
3. Asher, G. W., M. W. Fisher, S. L. Monfort, and G. E. Mylrea.1998. Endocrine control of reproduction in cervids: The enigma of temperate vs. tropical species. In Recent developments in deer biology, J. A. Milne (ed.). Macaulay Land Use Research Institute, Craigiebuckler, Aberdeen, UK, pp. 126-140.
4. Aspden, W. J., A. Rao, P. T. Scott, I. J. Clark, T. E. Trigg, J. Walsh, and M. J. D'Occhio. 1996. Direct actions of the luteinizing hormone-releasing hormone agonist, deslorelin, on anterior pituitary contents of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), LH and FSH subunit messenger ribonucleic acid, and plasma concentrations of LH and FSH in castrated male cattle. Biology of Reproduction 55: 386-392.
5. Aspden, W. J., A. Jackson, T. E. Trigg, and M. J. D'Occhio. 2003. Pituitary expression of LHB-and FSHβ-subunit mRNA, cellular distribution of LHB-subunit mRNA and LH and FSH synthesis during and after treatment with a gonadotrophin-releasing hormone agonist in heifers. Reproduction, Fertility and Development 15: 149-156.
6. Baker, D. L., M. A. Wild, M. M. Conner, H. B. Ravivarapu, R. L. Dunn, and T. M. Nett. 2002. Effects of GnRH agonist (leuprolide) on reproduction and behavior in female wapiti (Cervus elaphus nelsoni . Reproduction (Suppl.) 60: 155-167.
7. Baker, D. L., M. D. Hussain, R. L. Dunn, and T. M. Nett. 2003. Evaluation of remotely delivered leuprolide formulation as a contraceptive agent in captive female elk. Technical support for elk and vegetation management for Rocky Mountain National Park, Wildlife Research Report, Colorado Division of Wildlife, Fort Collins, Colorado, 125 pp.
8. Becker, S. E., and L. S. Katz. 1995. Effects of gonadotropin-releasing hormone agonist on serum LH concentrations in female white-tailed deer. Small Ruminant Research 18: 145-150.
9. Bergfeld, E. M., J. D'Occhio, and J. E. Kinder. 1996. Pituitary function, ovarian follicular growth, and plasma concentrations of 17 α-oestradiol and progesterone in prepubertal heifers during and after treatment with the luteinizing hormone-releasing hormone agonist deslorelin. Biology of Reproduction 54: 776-782.
10. Broekmans, F. J., P. G. Hompes, C. B. Lambalk, E. Broeders, and J. Schoemaker. 1996. Short-term desensitization: Effects of different doses of gonadotropin-releasing hormone agonist triptorelin. Human Reproduction 11: 55-60.
11. D'Occhio, M. J., W. J. Aspden, and T. R. Whyte. 1996. Controlled, reversible suppression of oestrous cycles in beef heifers and cows using agonist of luteinizing hormone-releasing hormone. Journal of Animal Science 74: 218-225.
12. D'Occhio, M. J., G. Fordyce, T. R. Whyte, W. J. Aspden, and T. E. Trigg. 2000. Reproductive responses of cattle to GnRH agonist. Animal Reproduction Science 60-61: 433-442.
13. D'Occhio, M. J., G. Fordyce, T. R. Whyte, T. F. Jubb, L. A. Fitzpatrick, N. J. Coper, W. J. Aspden, M. J. Bolam, and T. E. Trigg. 2002. Use of GnRH agonist implants for long-term suppression of fertility in extensively managed heifers and cows. Animal Reproduction Science 74: 151-162.
14. Dunn, R. L., J. P. English, D. R. Cowan, and D. P. Vanderbilt. 1994. Biodegradable in situ forming implants and methods of producing the same. US patent no. 5 278 201.
15. Fagerstone, K. A., M. A. Coffey, P D. Curtis, R. A. Dolbeer, G. J. Killian, L. A. Miller, and L. Wilmot. 2002. Wildlife fertility control. Wildlife Society Technical Review 02-2. The Wildlife Society, Bethesda, Maryland, USA, 53 pp.
16. Geist, V. 1981. Behavior: Adaptive strategies in mule deer. In Mule and black-tailed deer of North America, O. C. Wallmo (ed.). University of Nebraska Press, Lincoln, Nebraska, pp. 157-223.
17. Golly, F. B. 1957. Gestation period, breeding and fawning behavior of Columbian black-tailed deer. Journal of Mammalogy 38: 116-120.
18. Gong, J. G., B. K. Campbell, T. A. Bramley, C. G. Gutierrez, A. R. Peters, and R. Webb. 1996. Suppression in the secretion of follicle-stimulating hormone and luteinizing hormone, and ovarian follicle development in heifers continuously infused with gonadotropin-releasing hormone agonist. Biology of Reproduction 55: 68-74.
19. Hall, M. C., R. J. Fritzsch, A. I. Sagalowsky, A. Ahrens, B. Petty, and C. G. Roehrborn. 1999. Prospective determination of the hormonal response after cessation of luteinizing hormone-releasing hormone agonist treatment in patients with prostate cancer. Urology 53: 898-902.
20. Harder, J. D., and D. L. Moorhead. 1980. Development of corpora lutea and plasma progesterone levels associated with the onset of the breeding season in white-tailed deer (Odocoileus virginianus). Biology of Reproduction 22: 185-191.
21. Hazum, E., and P. M. Conn. 1988. Molecular mechanism of gonadotropin releasing hormone (GnRH) action. I. The GnRH receptor. Endocrine Review 9: 379-386.
22. Karten, M. J., and J. E. Rivier. 1986. Gonadotropin-releasing hormone analog design. Structure-function studies toward the development of agonists and antagonists: Rationale and perspectives. Endocrine Review 7: 44-66.
23. Kirkpatrick, J. F., and J. W. Turner. 1991. Reversible contraception in nondomestic animals. Journal of Zoo and Wildlife Medicine 22: 392-408.
24. Lefebvre, H. P., P. L. Toutain, J. P. Serthelon, V. Lassourd, L. Gardey, and J. P. Braun. 1994. Pharmacokinetic variables and bioavailability from muscle of creatinine kinase in cattle. American Journal of Veterinary Research 55: 487-497.
25. Lehner, P. N. 1996. Handbook of ethological methods, 2nd edition. Cambridge University Press, Cambridge, Massachusetts, 258 pp.
26. Littell, R. C., G. A. Milliken, W. W. Stroup, and R. D. Wolfinges. 1996. SAS® system for mixed models. SAS Institute Incorporated, Cary, North Carolina, USA.
27. Lunn, S. F., G. M. Cowen, K. D. Morris, and H. M. Fraser. 1992. Influence of the gonad on the degree of suppression induced by an LHRH agonist implant in the marmoset monkey. Journal of Endocrinology 132: 217-227.
28. Matsuo, H., Y. Baba, R. M. G. Nair, A. Arimura, and A. V. Schally. 1971. Structure of the porcine LH- and FSH-releasing hormone. I. The proposed amino acid sequence. Biochemical and Biophysical Research Communication 43: 1334-1339.
29. McNeilly, A. S., and H. M. Fraser. 1987. Effect of gonadotrophin-releasing hormone agonist-induced suppression of LH and FSH on follicle growth and corpus luteum function in the ewe. Journal of Endocrinology 115: 273-282.
30. McShea, W. J., S. L. Monfort, S. Hakim, J. F. Kirkpatrick, K. M. Liu, J. W. Turner, Jr., L. Chassy, and L. Munson. 1997. The effect of immunocontraception on the behavior and reproduction of white-tailed deer. Journal of Wildlife Management 61: 560-569.
31. Milliken, G. A., and D. E. Johnson. 1984. Analysis of messy data. Volume 1. Designed experiments. Lifetime Learning Publications, Belmont, California, 399 pp.
32. Montovan, S. M., P. P. Daels, J. Rivier, J. P Hughes, G. H. Stabenfeldt, and B. L. Lasley. 1990. The effect of potent GnRH agonist on gonadal and sexual activity in the horse. The riogenology 33: 1305-1321.
33. Morrison, J. A., C. E. Trainer, and P. L. Wright. 1976. Multivariate statistical methods. McGraw-Hill, New York, New York, 432 pp.
34. Muller, L. I., R. J. Warren, and D. L. Evans. 1997. Theory and practice of immunocontraception in wild mammals. Wildlife Society Bulletin 25: 504-514.
35. Naugle, R. E., A. T. Rutberg, H. B. Uunderwood, J. W. Turner, Jr., I. K. M. Lui. 2002. Field testing of immunocontraception on white-tailed deer (Odocoileus virginianus) on Fire Island National Seashore, New York, USA. Reproduction (Suppl.) 60: 143-153.
36. Nett, T. M., A. M. Akbar, R. D. Phemister, P. A. Holst, L. E. Reichert, Jr., and G. D. Niswender. 1975. Levels of luteinizing hormone, estradiol and progesterone in serum during the estrous cycle and pregnancy in the Beagle bitch. Proceedings of the Society of Experimental Biology and Medicine 148: 134-139.
37. Nett, T. M., M. E. Crowder, G. E. Moss, and T. M. Duello. 1981. GnRH-receptor interaction. V. Down-regulation of the pituitary receptors for GnRH in ovariectomized ewes by infusion of homologous hormone. Biology of Reproduction 24: 1145-1155.
38. Niswender, G. D. 1973. Influence of the site of conjugation on the specificity of antibodies to progesterone. Steroids 22: 413-424.
39. Ottoni, F. B. 2000. EthoLog 2.2: A tool for the transcription and timing of behavior observation sessions. Behavior Research Methods, Instruments, & Computers 32: 446-449.
40. Plotka, E. D., U. S. Seal, G. C. Schmoller, P. D. Karns, and K. D. Keenlyne. 1977. Reproductive steroids in the white-tailed deer ( Odocoileus virginianus borealis). I. Seasonal changes in the female. Biology of Reproduction 16: 340-343.
41. Ravivarapu, H. B., K. L. Moyer, and R. L. Dunn. 2000. Sustained activity and release of leuprolide acetate from an in situ forming polymeric implant. American Association of Pharmaceutical Scientist 1: 1-12.
42. Robinson, T. J. 1954. Relationship of oestrogen and progesterone in oestrous behavior of the ewe. Nature 173: 870-874.
43. Rutberg, A. T., R. E. Naugle, L. A. Thiele, and I. K. M. Liu. 2004. Effects of immunocontraception on a suburban population of white-tailed deer (Odocoileus virginianus). Biological Conservation 116: 243-250.
44. SAS Institute. 1997. SAS/STAT® user's guide 6.03 edition. SAS Institute, Inc., Cary, North Carolina, USA.
45. Shideler, S. E., M. A. Stoops, N. A. Gee, J. A. Howell, and B. L. Lasley. 2002. Use of porcine zona pellucida (PZP) vaccine as a contraceptive agent in free-ranging tule elk (Cervus elaphus nannodes . Reproduction (Suppl.) 60: 169-176.
46. Stills, H. F., Jr., and M. Q. Bailey. 1991. The use of Freund's complete adjuvant. Laboratory Animal 20: 25-30.
47. Trigg, T. F., P. J. Wright, A. F. Armour, P. E. Williamson, A. Junaidi, G. B. Martin, A. G. Doyle, and J. Walsh. 2001. Use of GnRH analogue implant to produce reversible long-term suppression of reproductive function in male and female domestic dogs. Journal of Reproduction and Fertility (Suppl.) 57: 255-261.
48. Wong, B., and K. L. Parker. 1988. Estrus in black-tailed deer. Journal of Mammalogy 69: 168-171.
49. Wood, A. J., I McCowan, and H. C. Nordan. 1962. Periodicity of growth in ungulates as shown by deer of the genus Odocoileus. Canadian Journal of Zoology 40:593-603.
50. Wood, A. K., R. E. Short, A. E. Darling, G. L. Dusek, R. G. Sasser, and C. A. Ruder. 1986. Serum assays for detecting pregnancy in mule and white-tailed deer. Journal of Wildlife Management 50: 684-687.