Aminopeptidase P2

Handbook of Proteolytic Enzymes, Second Edition: Volume 1: Aspartic and Metallo Peptidases

Volumn 1, Issue , 2004, Pages 934-937

  Simmons, William H ^a  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 13544276698     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-079611-3.50287-1     Document Type: Chapter

References (47)

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2. C. Blais Jr., J. Marc-Aurele, W.H. Simmons, G. Loute, P. Thibault, R.A. Skidgel and A. Adam (1999) Des-Arg9 -bradykinin metabolism in patients who presented hypersensitivity reactions during hemodialysis: role of serum ACE and aminopeptidase P. Peptides 20 421-430.
3. G.S. Cottrell, R.J. Hyde, J. Lim, M.R. Parsons, N.M. Hooper and A.J. Turner (2000) Identification of critical residues in the active site of porcine membrane-bound aminopeptidase P. Biochemistry 39 15129-15135.
4. J. Damas, J.-F. Leigeois and W.H. Simmons (1996) Potentiation of the pro-inflammatory effects of bradykinin by inhibition of angiotensin-converting enzyme and aminopeptidase P in rat paws. Naunyn-Schmiedeberg's Arch. Pharmacol. 354 670-676.
5. P. Dehm and A. Nordwig (1970) The cleavage of prolyl peptides by kidney peptidases. Partial purification of a ‘X-prolyl-aminopeptidase’ from swine kidney microsomes. Eur. J. Biochem. 17 364-371.
6. A. Dendorfer, S. Wolfrum, P. Wellhoner, K. Korsman and P. Dominiak (1997) Intravascular and interstitial degradation of bradykinin in isolated perfused rat heart. Br. J. Pharmacol. 122 1179-1187.
7. C. Ersahin and W.H. Simmons (1997) Inhibition of both aminopeptidase P and angiotensin-converting enzyme prevents bradykinin degradation in the rat coronary circulation. J. Cardiovasc. Pharmacol. 30 96-101.
8. C. Ersahin, D.E. Euler and W.H. Simmons (1999) Cardioprotective effects of the aminopeptidase P inhibitor apstatin: studies on ischemia/reperfusion injury in the isolated rat heart. J. Cardiovasc. Pharmacol. 34 604-611.
9. Ersahin, C., Szpaderska, A.M. & Simmons, W.H. (2002a) Sequence of rat and mouse membrane aminopeptidase P. 16th International Conference on the Kallikrein Kinin System, p. 108.
10. Ersahin, C., Szpaderska, A.M., Taylor-McCabe, K.J., Orawski, A.T. & Simmons, W.H. (2002b) Aminopeptidase P isozymes in human heart. 16th International Conference on the Kallikrein Kinin System, p. 107.
11. J.A. Griswold, C.V. Beall, C.R.F. Baker Jr., D.T. Little, G.H. Little and F.J. Behal (1996) Bradykinin metabolism in the liver and lung of the rat. J. Surg. Res. 66 12-20.
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14. N.M. Hooper and A.J. Turner (1989) Hydrolysis of the glycosylphosphatidylinositol anchors of renal microvillar peptidases by a plasma phospholipase D. Biochem. Soc. Trans. 17 885-886.
15. N.M. Hooper, J. Hryszko and A.J. Turner (1990) Purification and characterization of pig kidney aminopeptidase P: a glycosylphosphatidylinositol-anchored ectoenzyme. Biochem. J. 267 509-515.
16. N.M. Hooper, J. Hryszko, S.Y. Oppong and A.J. Turner (1992) Inhibition by converting enzyme inhibitors of pig kidney aminopeptidase P. Hypertension 19 281-285.
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18. K. Kim, S. Kumar, W.H. Simmons and N.J. Brown (2000) Inhibition of aminopeptidase P potentiates wheal response to bradykinin in angiotensin-converting enzyme inhibitor-treated humans. J. Pharmacol. Exp. Ther. 292 295-298.
19. S. Kitamura, L.A. Carbini, W.H. Simmons and A.G. Scicli (1999) Effects of aminopeptidase P inhibition on kinin-mediated vasodepressor responses. Am. J. Physiol. 276 H1664-H1671.
20. A. Kudoh, E. Kudoh, H. Katagai and T. Takazawa (2001) Effects of the aminopeptidase P inhibitor apstatin on bradykinin-induced inositol 1,4,5-triphosphate in neonatal rat cardiomyocytes. J. Cardiovasc. Pharmacol. 37 495-501.
21. J. Lasch, S. Moschner, H. Sann, S. Zellmer and R. Koelsch (1998) Aminopeptidase P – a cell-surface antigen of endothelial and lymphoid cells: catalytic and immuno-histotopical evidences. Biol. Chem. 379 705-709.
22. J. Lefebvre, L.J. Murphey, T.V. Hartert, R.J. Shan, W.H. Simmons and N.J. Brown (2002) Dipeptidyl peptidase IV activity in patients with ACE-inhibitor-associated angioedema. Hypertension 39 460-464.
23. G.S. Lloyd, J. Hryszko, N.M. Hooper and A.J. Turner (1996) Inhibition and metal ion activation of pig kidney aminopeptidase P: dependence on nature of substrate. Biochem. Pharmacol. 52 229-236.
24. L.L. Maggiora, A.T. Orawski and W.H. Simmons (1999) Apstatin analog inhibitors of aminopeptidase P, a bradykinin-degrading enzyme. J. Med. Chem. 42 2394-2402.
25. H. Matsumoto, R.H. Erickson and Y.S. Kim (1995) Localization and characterization of rat small intestinal aminopeptidase P and its role in prolyl peptide digestion. J. Nutr. Biochem. 6 104-110.
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28. A.T. Orawski and W.H. Simmons (1995) Purification and properties of membrane-bound aminopeptidase P from rat lung. Biochemistry 34 11227-11236.
29. E.T. Parkin, A.J. Turner and N.M. Hooper (1996) Isolation and characterization of two distinct low-density, Triton-insoluble, complexes from porcine lung membranes. Biochem. J. 319 887-896.
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31. M.M. Prechel, A.T. Orawski, L.L. Maggiora and W.H. Simmons (1995) Effect of a new aminopeptidase P inhibitor, apstatin, on bradykinin degradation in the rat lung. J. Pharmacol. Exp. Ther. 275 1136-1142.
32. R.L. Prueitt, J.L. Ross and A.R. Zinn (2000) Physical mapping of nine Xq translocation breakpoints and identification of XPNPEP2 as a premature ovarian failure candidate gene. Cytogenet. Cell. Genet. 89 44-50.
33. J.W. Ryan, F. Valido, P. Berryer, A.Y.K. Chung and J.E. Ripka (1992) Purification and characterization of guinea pig serum aminoacylproline hydrolase (aminopeptidase P). Biochim. Biophys. Acta 1119 140-147.
34. J.W. Ryan, P. Berryer, A.Y.K. Chung and D.H. Sheffy (1994) Characterization of rat pulmonary vascular aminopeptidase P in vivo: role in the inactivation of bradykinin. J. Pharmacol. Exp. Ther. 269 941-947.
35. J.W. Ryan, N.D. Denslow, J.A. Greenwald and M.A. Rogoff (1994) Immunoaffinity purifications of aminopeptidase P from guinea pig lungs, kidney and serum. Biochem. Biophys. Res. Commun. 205 1796-1802.
36. J.W. Ryan, A. Papapetropoulos, H. Ju, N.D. Denslow, A. Antonov, R. Virmani, F.D. Kolodgie, R.G. Gerrity and J.D. Catravas (1996) Aminopeptidase P is disposed on human endothelial cells. Immunopharmacology 32 149-152.
37. W.H. Simmons and A.T. Orawski (1992) Membrane-bound aminopeptidase P from bovine lung: its purification, properties, and degradation of bradykinin. J. Biol. Chem. 267 4897-4903.
38. T.J. Sprinkle, A.A. Stone, R.C. Venema, N.D. Denslow, C. Caldwell and J.W. Ryan (1998) Assignment of the membrane-bound human aminopeptidase P gene (XPNPEP2) to chromosome Xq25. Genomics 50 114-116.
39. K.J. Taylor-McCabe and W.H. Simmons (2000) Separation of aminopeptidase P isozymes in human heart tissue and serum. J. Hypertens. 18(suppl 4), S62.
40. K.J. Taylor-McCabe, C. Ersahin and W.H. Simmons (2001) Bradykinin metabolism in the isolated perfused rabbit heart. J. Hypertens. 19 1295-1299.
41. G. Vanhoof, R. Goossens, I. De Meester, D. Hendriks and S. Scharpé (1995) Proline motifs in peptides and their biological processing. FASEB J. 9 736-744.
42. R.C. Venema, H. Ju, R. Zou, V.J. Venema and J.W. Ryan (1997) Cloning and tissue distribution of human membrane-bound aminopeptidase P. Biochim. Biophys. Acta 1354 45-48.
43. C. Vergas Romero, I. Neudorfer, K. Mann and W. Schafer (1995) Purification and amino acid sequence of aminopeptidase P from pig kidney. Eur. J. Biochem. 229 262-269.
44. M.C.J. Wilce, C.S. Bond, N.E. Dixon, H.C. Freeman, J.M. Guss, P.E. Lilley and J.A. Wilce (1998) Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli. Proc. Natl. Acad. Sci. USA 95 3472-3477.
45. S. Wolfrum, G. Richardt, P. Dominiak, H.A. Katus and A. Dendorfer (2001) Apstatin, a selective inhibitor of aminopeptidase P, reduces myocardial infarct size by a kinin-dependent pathway. Br. J. Pharmacol. 134 370-374.
46. A. Yaron and F. Naider (1993) Proline-dependent structural and biological properties of peptides and proteins. Crit. Rev. Biochem. Mol. Biol. 28 31-81.
47. T. Yoshimoto, A.T. Orawski and W.H. Simmons (1994) Substrate specificity of aminopeptidase P from Escherichia coli: comparison with membrane-bound forms from rat and bovine lung. Arch. Biochem. Biophys. 311 28-34.