Agonist "flare-up" versus antagonist in the management of poor responders undergoing in vitro fertilization treatment

Fertility and Sterility

Volumn 83, Issue 2, 2005, Pages 331-335

  Mohamed, Kamel A ^a   Davies, W A R ^a   Allsopp, Julian ^a   Lashen, Hany ^b  

^a BMI Three Shires Hospital   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Agonist; Antagonist; Flare up; IVF; Poor responders

Indexed keywords

CHORIONIC GONADOTROPIN; PROSTAGLANDIN E2;

ADULT; ARTICLE; CLINICAL PROTOCOL; COMPARATIVE STUDY; CONTROLLED STUDY; EMBRYO; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; HEALTH CENTER; HUMAN; INFERTILITY; INTRACYTOPLASMIC SPERM INJECTION; MAJOR CLINICAL STUDY; OVARY FUNCTION; PREGNANCY RATE; PRIORITY JOURNAL; PROSTAGLANDIN BLOOD LEVEL; RETROSPECTIVE STUDY; STANDARDIZATION; TREATMENT OUTCOME;

EID: 13544273400     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2004.07.963     Document Type: Article

References (18)

1. J. Land, M. Yarmolinskaya, J. Dumoulin, J. Evers Higher dose menopausal gonadotrophin stimulation in poor responders does not improve in vitro fertilization outcome Fertil Steril 65 1996 961 965
2. H. Lashen, W. Ledger, A. Bernal, B. Evan, D. Barlow Super ovulation with high gonadotrophin dose for invitro fertilization, is it effective? J Assisted Reprod Genet 15 1998 438 443
3. S. Padilla, K. Dugan, V. Maruschak, S. Shalika, R. Smith Use of the flare up protocol with high dose human follicle stimulating hormone and human menopausal gonadotrophin for IVF in poor responders Fertil Steril 65 1996 796 799
4. V. Karande, R. Morris, J. Rinehart, C. Miller, R. Rao, N. Gleicher Limited success using the flare protocol in poor responders in cycles with low basal follicle stimulating hormone levels during in vitro fertilization Fertil Steril 67 1997 900 903
5. E. Surrey, J. Bower, D. Hill, J. Ramsey, M. Surrey Clinical and endocrine effects of a microdose GnRH agonist flare regimen administered to poor responders who are undergoing in vitro fertilization Fertil Steril 69 1998 419 424
6. W. Schoolcraft, T. Schlenker, M. Gee, J. Stevens, L. Wagley Improved controlled ovarian hyperstimulation in poor responders in vitro fertilization patients with a microdose follicle stimulating hormone flare, growth hormone protocol Fertil Steril 67 1997 93 97
7. I. Craft, A. Gorgy, J. Hill, D. Menon, B. Podsiadly Will GnRH antagonists provide new hope for patients considered difficult responders to GnRH agonist protocols? Hum Reprod 14 1999 2959 2962
8. M. Akman, H. Erden, S. Tosun, N. Bayazit, E. Akosy, M. Bahceci Addition of GnRH antagonist in cycles of poor responders undergoing IVF Hum Reprod 15 2000 2145 2147
9. N. Nikolettos, S. Al-Hassani, R. Felberbaum, L. Damirel, W. Kupker, P. Montzka Gonadotrophin-releasing hormone antagonist protocol: a novel method of ovarian stimulation in poor responders Eur J Obstet Gyn Reprod Biol 97 2001 202 207
10. R. Felberbaum, C. Albano, M. Ludwig, H. Riethmuller-Winzen, M. Grigat, P. Devroey Ovarian stimulation for assisted reproduction with HMG and concomitant midcycle administration of the GnRH antagonist cetrorelix according to the multiple dose protocol: a prospective uncontrolled phase III study Hum Reprod 15 2000 1015 1020
11. The European and Middle East Orgalutran Study Group Comparable clinical outcome using the GnRH antagonist ganirelix or a long protocol of the GnRH agonist triptorelin for the prevention of premature LH surges in women undergoing ovarian stimulation Hum Reprod 16 2001 644 651
12. F. Olivennes, B. Mannaerts, M. Struijs, M. Bonduelle, P. Devroey Perinatal outcome of pregnancy after GnRH antagonist (ganirelix) treatment during ovarian stimulation for conventional IVF or ICSI: a preliminary report Hum Reprod 16 2001 1588 1591
13. M. Akman, H. Erden, S. Tosun, N. Bayazit, E. Akosy, M. Behceci Comparison of agonistic flare up protocol and antagonistic multiple dose protocol in ovarian stimulation of poor responders: results of a prospective randomized trial Hum Reprod 16 2001 868 870
14. E. Surrey, W. Schoolcraft Evaluating strategies for improving ovarian response of the poor responder undergoing assisted reproduction techniques Fertil Steril 73 2000 667 676
15. R. Fleming, F. Lloyd, M. Herbert, J. Fenwick, T. Griffith, A. Murdoch Effect of profound suppression of luteinising hormone during ovarian stimulation on follicular activity, oocyte and embryo function in cycles stimulated with purified follicle stimulating hormone Hum Reprod 13 1998 1788 1792
16. R. Scott, G. Hofmann Prognostic assessment of ovarian reserve Fertil Steril 63 1995 1 11
17. L. Bancsi, F. Broekmans, M. Eijkemans, F. de Jong, J. Habbema, E. te Velde Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve Fertil Steril 77 2002 328 336
18. J. Garecia-Velasco, V. Isaza, C. Vidal, A. Landazabal, J. Remohi, C. Simon Human ovarian steroid secretion in vivo: effects of GnRH agonist versus antagonist (cetrorelix) Hum Reprod 16 2001 2533 2539