Latent membrane protein 1 deletion mutants accumulate in Reed-Sternberg cells of human immunodeficiency virus-related Hodgkin's lymphoma

Journal of Virology

Volumn 79, Issue 4, 2005, Pages 2643-2649

  Guidoboni, Massimo ^a   Ponzoni, Maurilio ^b   Caggiari, Laura ^a   Lettini, Antonia A ^a   Vago, Luca ^c   De Re, Valli ^a   Gloghini, Annunziata ^a   Zancai, Paola ^a   Carbone, Antonino ^a   Boiocchi, Mauro ^a   Dolcetti, Riccardo ^a  

^a CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^b Ctr of Cell and Molec Pharmacol   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LATENT MEMBRANE PROTEIN 1;

ARTICLE; CONTROLLED STUDY; DELETION MUTANT; EPSTEIN BARR VIRUS; HODGKIN DISEASE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN TISSUE; IN VIVO STUDY; ITALY; MICRODISSECTION; NUCLEOTIDE SEQUENCE; PREVALENCE; PRIORITY JOURNAL; REED STERNBERG CELL; TUMOR CELL; VIRUS STRAIN;

CARRIER PROTEINS; GENE DELETION; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 4, HUMAN; HODGKIN DISEASE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOMA, AIDS-RELATED; REED-STERNBERG CELLS;

HUMAN HERPESVIRUS 4; HUMAN IMMUNODEFICIENCY VIRUS; PHRAGMITES; RNA VIRUSES;

EID: 13444304273     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.79.4.2643-2649.2005     Document Type: Article

References (31)

1. Audouin, J., J. Diebold, and G. Pallesen. 1992. Frequent expression of Epstein-Barr virus latent membrane protein-1 in tumour cells of Hodgkin's disease in HIV-positive patients. J. Pathol. 167:381-384.
2. Bellas, C., A. Santon, A. Manzanal, E. Campo, C. Martin, A. Acevedo, C. Varona, J. Forteza, M. Morente, and C. Montalban. 1996. Pathological, immunological, and molecular features of Hodgkin's disease associated with HIV infection. Comparison with ordinary Hodgkin's disease. Am. J. Surg. Pathol. 20:1520-1524.
3. Berger, C., P. Brousset, C. McQuain, and H. Knecht. 1997. Deletion variants within the NF-kB activation domain of the LMP1 oncogene in acquired immunodeficiency syndrome-related large cell lymphomas, in prelymphomas and atypical lymphoproliferations. Leuk. Lymphoma 26:239-250.
4. Carbone, A., A. Gloghini, G. Gaidano, A. M. Cilia, P. Bassi, P. Polito, E. Vaccher, G. Saglio, and U. Tirelli. 1995. AIDS-related Burkitt's lymphoma. Morphologic and immunophenotypic study of biopsy specimens. Am. J. Clin. Pathol. 103:561-567.
5. Carbone, A., G. Gaidano, A. Gloghini, L. M. Larocca, D. Capello, V. Canzonieri, A. Antinori, U. Tirelli, B. Falini, and R. Dalla-Favera. 1998. Differential expression of BCL-6, CD138/syndecan-1 and EBV-encoded latent membrane protein-1 identifies distinct histogenetic subsets of acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas. Blood 91:747-755.
6. Chen, M. L., C. N. Tsai, C. L. Liang, C. H. Shu, C. R. Huang, D. Sulitzeanu, S. T. Liu, and Y. S. Chang. 1992. Cloning and characterization of the latent membrane protein (LMP) of a specific Epstein-Barr virus variant derived from the nasopharyngeal carcinoma in the Taiwanese population. Oncogene 7:2131-2140.
7. Dietmaier, W., A. Hartmann, S. Wallinger, E. Heinmoller, T. Kerner, E. Endl, K.-W. Jauch, F. Hofstadter, and J. Ruschoff. 1999. Multiple mutation analysis in single tumor cells with improved whole genome amplification. Am. J. Pathol. 154:83-95.
8. Dolcetti, R., M. Boiocchi, A. Gloghini, and A. Carbone. 2001. Pathogenetic and histogenetic features of HIV-associated Hodgkin's disease. Eur. J. Cancer 37:1276-1287.
9. Dolcetti, R., M. Quaia, A. Gloghini, V. De Re, P. Zancai, R. Cariati, L. Babuin, A. M. Cilia, S. Rizzo, A. Carbone, and M. Boiocchi. 1999. Biologically relevant phenotypic changes and enhanced growth properties induced in B lymphocytes by an EBV strain derived from a histologically aggressive Hodgkin's disease. Int. J. Cancer 80:240-249.
10. Dolcetti, R., P. Zancai, V. De Re, A. Gloghini, B. Bigoni, B. Pivetta, S. De Vita, A. Carbone, and M. Boiocchi. 1997. Epstein-Barr virus strains with latent membrane protein-1 deletions: prevalence in the Italian population and high association with human immunodeficiency virus-related Hodgkin's disease. Blood 89:1723-1731.
11. Eliopoulos, A. G., and A. B. Rickinson. 1998. Epstein-Barr virus: LMP1 masquerades as an active receptor. Curr. Biol. 8:R196-R198.
12. Essop, M. F., M. Engel, P. Close, C. Sinclair-Smith, and G. Pallesen. 1999. Epstein-Barr virus in Hodgkin's disease: frequency of a 30-bp deletion in the latent membrane protein (LMP-1) oncogene in South African patients. Int. J. Cancer 84:449-451.
13. Hayashi, K., W. G. Chen, Y. Y. Chen, M. M. Bacchi, M. Alvarenga, E. S. Abreu, K. L. Chang, and L. M. Weiss. 1997. Deletion of the Epstein-Barr virus latent membrane protein 1 gene in United States and Brazilian Hodgkin's disease and reactive lymphoid tissue: high frequency of a 30-bp deletion. Hum. Pathol. 28:1408-1414.
14. Herndier, B. G., H. C. Sanchez, K. L. Chang, Y. Y. Chen, and L. M. Weiss. 1993. High prevalence of Epstein-Barr virus in the Reed-Sternberg cells of HIV-associated Hodgkin's disease. Am. J. Pathol. 142:1073-1079.
15. Hu, L. F., E. R. Zabarovsky, F. Chen, S. L. Cao, I. Ernberg, G. Klein, and G. Winberg. 1991. Isolation and sequencing of the Epstein-Barr virus BNLF-1 gene (LMP1) from a Chinese nasopharyngeal carcinoma. J. Gen. Virol. 72:2399-2409.
16. Hu, L. F., F. Chen, X. Zheng, I. Ernberg, S. L. Cao, B. Christensson, G. Klein, and G. Winberg. 1993. Clonability and tumorigenicity of human epithelial cells expressing the EBV encoded membrane protein LMP1. Oncogene 8:1575-1583.
17. International Agency for Research on Cancer. 1997. IARC monographs on the evaluation of carcinogenic risks to humans, vol. 70. Epstein-Barr virus and Kaposi's sarcoma herpesvirus/human herpesvirus 8. International Agency for Research on Cancer/World Health Organization, Lyon, France.
18. Kim, L. H., S. C. Peh, and S. Poppema. 2003. Dual variant of Epstein-Barr virus in Hodgkin/Reed-Sternberg cells: single-cell PCR study on latent membrane protein-1 gene. Int. J. Cancer 107:250-255.
19. Knecht, H., E. Bachmann, P. Brousset, K. Sandvej, D. Nadal, F. Bachmann, B. F. Odermatt, G. Delsol, and G. Pallesen. 1993. Deletions within the LMP1 oncogene of Epstein-Barr virus are clustered in Hodgkin's disease and identical to those observed in nasopharyngeal carcinoma. Blood 82:2937-2942.
20. Knecht, H., E. Bachmann, D. J. Joske, R. Sahli, A. Emery-Goodman, J. L. Casanova, M. Zilic, F. Bachmann, and B. F. Odermatt. 1993. Molecular analysis of LMP (latent membrane protein) oncogene in Hodgkin's disease. Leukemia 7:580-585.
21. Lin, J. C., S. C. Lin, B. K. De, W. C. Chan, B. L. Evatt, and W. C. Chan. 1993. Precision of genotyping of Epstein-Barr virus by polymerase chain reaction using three gene loci (EBNA-2, EBNA-3C, and EBER): predominance of type A virus associated with Hodgkin's disease. Blood 81:3372-3381.
22. Sandvej, K., S. C. Peh, B. S. Andresen, and G. Pallesen. 1994. Identification of potential hot spots in the carboxy-terminal part of the Epstein-Barr virus (EBV) BNLF-1 gene in both malignant and benign EBV-associated diseases: high frequency of a 30-bp deletion in Malaysian and Danish peripheral T-cell lymphomas. Blood 84:4053-4060.
23. Santon, A., and C. Bellas. 2001. Deletions within the Epstein-Barr virus latent membrane protein-1 oncogene in adult ordinary, HIV-associated and paediatric Hodgkin's disesase. Leuk. Lymphoma 40:235-242.
24. Santon, A., C. M. Martin, A. I. Manzanal, M. V. Preciado, and C. Bellas. 1998. Paediatric Hodgkin's disease in Spain: association with Epstein-Barr strains carrying latent membrane protein-1 oncogene deletions and high frequency of dual infections. Br. J. Haematol. 103:129-136.
25. Smir, B. N., R. J. Hauke, P. J. Bierman, T. G. Gross, F. d'Amore, J. R. Anderson, and T. C. Greiner. 1996. Molecular epidemiology of deletions and mutations of the latent membrane protein 1 oncogene of the Epstein-Barr virus in posttransplant lymphoproliferative disorders. Lab. Investig. 75:575-588.
26. Tirelli, U., D. Errante, R. Dolcetti, A. Gloghini, D. Serraino, E. Vaccher, S. Franceschi, M. Boiocchi, and A. Carbone. 1995. Hodgkin's disease and human immunodeficiency virus infection: clinicopathologic and virologie features of 114 patients from the Italian Cooperative Group on AIDS and Tumors. J. Clin. Oncol. 13:1758-1767.
27. Trivedi, P., L. F. Hu, F. Chen, B. Christensson, M. G. Masucci, G. Klein, and G. Winberg. 1994. Epstein-Barr virus (EBV)-encoded membrane protein LMP1 from a nasopharyngeal carcinoma is non-immunogenic in a murine model system, in contrast to a B cell-derived homologue. Eur. J. Cancer 30A:84-88.
28. Trivedi, P., G. Winberg, and G. Klein. 1997. Differential immunogenicity of Epstein-Barr virus (EBV) encoded growth transformation-associated antigens in a murine model system. Eur. J. Cancer 33:912-917.
29. Uccini, S., F. Monardo, L. P. Ruco, C. D. Baroni, A. Faggioni, A. M. Agliano, A. Gradilone, V. Manzari, L. Vago, G. Costanzi, A. Carbone, M. Boiocchi, and V. De Re. 1989. High frequency of Epstein-Barr virus genome in HIV-positive patients with Hodgkin's disease. Lancet i:1458.
30. Walling, D. M., N. Shebib, S. C. Weaver, C. M. Nichols, C. M. Flaitz, and J. Webster-Cyriaque. 1999. The molecular epidemiology and evolution of Epstein-Barr virus: sequence variation and genetic recombination in the latent membrane protein-1 gene. J. Infect. Dis. 179:763-774.
31. Webster-Cyriaque, J., J. Middeldorp, and N. Raab-Traub. 2000. Hairy leukoptakia: an unusual combination of transforming and permissive Epstein-Barr virus infections. J. Virol. 74:7610-7618.