Multiple pituitary hormone deficiency (MPHD) associated with normal height, absent puberty and obesity

Pediatric Endocrinology Reviews

Volumn 1, Issue SUPPL. 3, 2004, Pages 505-507

  Doknic, Mirjana ^a   Pekic, Sandra ^a   Djurovic, Marina ^a   Zivkovic, Vladimir ^a   Popovic, Vera ^a  

^a CLINICAL CENTER OF SERBIA   (Serbia)

Author keywords

Growth hormone deficiency; Growth without growth hormone; IGF I deficiency

Indexed keywords

HYDROCORTISONE; LEVOTHYROXINE; SEX HORMONE; SOMATOMEDIN C;

ADULT; CASE REPORT; CONFERENCE PAPER; FEMALE; GROWTH HORMONE DEFICIENCY; HEIGHT; HORMONE DEFICIENCY; HORMONE SUBSTITUTION; HUMAN; MULTIPLE PITUITARY HORMONE DEFICIENCY; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PUBERTY DISORDERS;

ADULT; AMENORRHEA; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPOPITUITARISM; INSULIN-LIKE GROWTH FACTOR I; OBESITY; PITUITARY HORMONES; PUBERTY, DELAYED;

EID: 13444302757     PISSN: 15654753     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (13)

1. Wu W, Cogan J, Dasen J, Frisch H, O'Conell S, Flynn S, Brown M, Mullis P, Parks J, Phillips J, Rosenfeld M. Mutations in PROP 1 cause familial combined pituitary hormone deficiency. Nature Genetics 1998;18:437-443
2. Arroyo A, Pernasetti F, Vasilyev VV, Amato P, Yen SC, Mellon P. A unique case of combined pituitary hormone deficiency caused by PROP1 gene mutation (R120C) associated with normal height and absent puberty. Clin Endocrinol 2002;57:283-291
3. Ouden DT, Kroon M, Hoogland P, Wit JM. A 43-years old male with untreated panhypopituitarism due to absence of the pituitary stalk: from dwarf to giant. J Clin Endocrinol Metab 2002;87:5430-5434
4. Lazar L, Dan S, Phillip M. Growth without growth hormone: growth pattern and final height of five patients with idiopathic combined pituitary hormone deficiency. Clin Endocrinol 2003;59:82-88
5. Krzisnik C, Kolacio Z, Battelino T, Brown M, Parks J, Laron Z. The "Little People" of the island of Krk-revisited etiology of hypopituitarism revealed. J Endocrine Genetics 1999;1:9-19
6. Laron Z. Insulin like growth factor (IGF-1) and insulin as growth hormones. Novartis Foundation Symp. Biology of IGF-1 John Wiley & Sons Ltd 2004 (in press)
7. Maor G, Segev Y, Phillip M. Leptin acts as a growth factor on the chondoocytes and skeletal growth. J Bone Metab Res 2002;17:1034-1043
8. Hathout EH, Baylink DJ, Mohan S. Normal growth despite GH, IGF I and IGF II deficiency. Growth Hormone & IGF Res 1999;9:272-277
9. Geffner ME. The growth without growth hormone syndrome. Endocrinol Metab Clin North America 1996;25:649-663
10. Smith E, Boyd J, Frank G, Takahashi H, Cohen R, Specker B, Williams T, Lubahan D, Korach K. Estrogen resistance caused by mutation in the estrogen - receptor gene in man. N Engl J Med 1994;331:1056-1061
11. Delhanty PJD, van der Eerden BCJ, Gauna C, van Leewen JPTM, van der Lely AJ. Ghrelin is expressed in human bone and enhances the proliferation of human osteoblasts. Growth hormone & IGF Res 2004;14:abstract 082
12. Lehto-Axtelius D, Chen D, Surve VV, Hakanson R. Post-gastrectomy osteopenia in the rat: bone structure is preserved by retaining 1035-30% of the oxyntic gland area. Scand J Gastroenterol 2002;37:437-443
13. Broglio F, Koetsveld P, Benso A, Gottero C, Prodam F, Papotti M, Muccioli G, Gauna C, Holand L, Deghenghi R, Arvat E, Van Der Lely AJ, Ghigo E. J Clin Endocrinol Metab 2002;87:4829-4832