Vitamin C deficiency in cancer patients

Palliative Medicine

Volumn 19, Issue 1, 2005, Pages 17-20

  Mayland, Catriona R ^a   Bennett, Michael I ^a   Allan, Keith ^b  

^a St Gemma's Hospice   (United Kingdom)

^b LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

Author keywords

Ascorbic acid; Cancer; Inflammatory response; Vitamin C

Indexed keywords

ALBUMIN; ASCORBIC ACID; C REACTIVE PROTEIN;

ADVANCED CANCER; AGED; ANAMNESIS; ARTICLE; ASCORBIC ACID DEFICIENCY; CANCER PATIENT; CANCER SURVIVAL; CLINICAL ARTICLE; DEMOGRAPHY; DIETARY INTAKE; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; MALE; PREVALENCE; SMOKING; THROMBOCYTE COUNT; VITAMIN BLOOD LEVEL;

ACUTE DISEASE; AGED; ASCORBIC ACID; ASCORBIC ACID DEFICIENCY; DIET; ENGLAND; FEMALE; HOSPICE CARE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; NUTRITIONAL STATUS; PREVALENCE; SERUM ALBUMIN;

EID: 13444301515     PISSN: 02692163     EISSN: None     Source Type: Journal    
DOI: 10.1191/0269216305pm970oa     Document Type: Article

References (16)

1. Hoffbrand AV. Disorders of the blood. In Weatherall DJ, Ledingham JGG, Warrell DA eds. Oxford textbook of medicine, third edition. Oxford: Oxford University Press, 1996: 3373-702.
2. Rivlin RS. Disorders of vitamin metabolism: deficiencies, metabolic abnormalities and excesses. In Wyngarearden JB, Smith Lloyd H, Bennett J C eds. Cecil textbook of medicine, eighteenth edition. Philadelphia, PA: WB Saunders Company, 1988: 1228-40.
3. Department of Health. Dietary reference values for food energy and nutrients for the United Kingdom. Report of the Panel on Dietary Reference Values of the Committee on Medical Aspects of Food Policy. London: HMSO, 1991: 117-22.
4. Reuler JB, Broudy VC, Cooney TG. Adult scurvy. JAMA 1985; 6: 805-806.
5. Neuenschwander H, Bruera E. Asthenia. In Doyle D, Hanks GWC, MacDonald N eds. Oxford textbook of palliative medicine, second edition. Oxford: Oxford University Press, 1998: 573-82.
6. Clark ML. Nutrition. In Kumar P, Clark M eds. Clinical medicine, fourth edition. London: WB Saunders, 1998: 198-216.
7. Fain O, Mathieu E, Thomas M. Scurvy in patients with cancer. BMJ 1998; 316: 1661-62.
8. Yalcin A, Ural A, Beyan C, Bulent T, Demiriz M, Turker C. Scurvy presenting with cutaneous and articular signs and decrease in red and white blood cells. Int J Dermatol 1996; 35: 879-80.
9. Bennett M, Ryall N. Using the modified Barthel index to estimate survival in cancer patients in hospice: observational study. BMJ 2000; 321: 1381-82.
10. McCance RA, Widdowson EM. The composition of foods, fifth edition (revised and extended). London: Royal Society of Chemistry, 1991.
11. Tessier F, Birlouez-Aragon I, Tjani C, Guilland J-C. Validation of a micromethod for determining oxidized and reduced vitamin C in plasma by HPLC-fluorescence. Int J Vitam Nutr Res 1996; 66 166-70.
12. Jacob RA. Assessment of human vitamin C status. J Nutr 1990; 120: 1480-85.
13. Galloway P, McMillan DC, Sattar N. Effect of the inflammatory response on trace element and vitamin status. Ann Clin Biochem 2000; 37: 289-97.
14. Schorah CJ, Downing C, Piripitsi A, et al. Total vitamin C, ascorbic acid and dehydroascorbic acid concentrations in plasma of critically ill patients. Am J Clin Nutr 1996; 63: 760-65.
15. Creagan ET, Moertel CG, O'Fallon JR, et al. Failure of high-dose vitamin C therapy to benefit patients with advanced cancer. A controlled trial. N Engl J Med 1979; 301: 687-90.
16. Moertel CG, Fleming TR, Creagan ET, Rubin J, O'Connell MJ, Ames MM. High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. N Engl J Med 1985; 312: 137-41.