Elimination of major side effects due to ROS of therapeuticals through biotransformation control of the 57 cytochromes P450 isoenzymes

Medical Hypotheses

Volumn 64, Issue 4, 2005, Pages 802-805

  Wiseman, Alan ^a  

^a UNIVERSITY OF SURREY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANASTROZOLE; CLOTRIMAZOLE; CYTOCHROME P450; ESTROGEN; HEMATIN; IMIDAZOLE DERIVATIVE; INSULIN; INTEGRASE INHIBITOR; LANOSTEROL; MICONAZOLE; MORPHINE; REACTIVE SULFUR SPECIES; SAQUINAVIR; TAMOXIFEN; TESTOSTERONE; UNSPECIFIC MONOOXYGENASE; VACCINE; WARFARIN;

ARTICLE; CANCER; CELL BASED GENE THERAPY; CELL CULTURE; DRUG TRANSFORMATION; HEART INJURY; INSULIN DEPENDENT DIABETES MELLITUS; NONVIRAL GENE THERAPY; OSTEOPOROSIS; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN ENGINEERING; SITE DIRECTED MUTAGENESIS;

EID: 13444301289     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2004.10.010     Document Type: Article

References (10)

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6. Y. Hu, S.S. Dehai, G. Hynd, G.P. Jones, and D. Kupfer CYP2D6-mediated catalysis of tamoxifen aromatic hydroxylation with an NIH shift similar to hydroxylation mechanisms in chicken, rat and human liver microsomes Xenobiotica 33 2003 141 151
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