Alkylamino derivatives of 4-aminomethylpyridine as inhibitors of copper-containing amine oxidases

Journal of Medicinal Chemistry

Volumn 48, Issue 3, 2005, Pages 664-670

  Bertini, Vincenzo ^a   Buffoni, Franca ^b   Ignesti, Giovanni ^b   Picci, Nevio ^c   Trombino, Sonia ^c   Iemma, Francesca ^c   Alfei, Silvana ^a   Pocci, Marco ^a   Lucchesini, Francesco ^a   De Munno, Angela ^d  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF CALABRIA   (Italy)

^d UNIVERSITY OF PISA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

3 (1 PIPERIDINYL) 4 AMINOMETHYLPYRIDINE; 3 [(1 METHYLETHYL)AMINO] 4 AMINOMETHYLPYRIDINE; 3 AMINO 4 AMINOMETHYLPYRIDINE; 3 CYCLOHEPTYLAMINO 4 AMINOMETHYLPYRIDINE; 3 CYCLOHEXYLAMINO 4 AMINOMETHYLPYRIDINE; 3 CYCLOHEXYLMETHYLAMINO 4 AMINOMETHYLPYRIDINE; 3 CYCLOPENTYLAMINO 4 AMINOMETHYLPYRIDINE; 3 CYCLOPROPYLAMINO 4 AMINOMETHYLPYRIDINE; 3 ETHYLAMINO 4 AMINOMETHYLPYRIDINE; 3 METHYLAMINO 4 AMINOMETHYLPYRIDINE; ALKYL GROUP; AMINE OXIDASE (COPPER CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING); BENZYLAMINE OXIDASE; MONOAMINE OXIDASE INHIBITOR; PICOLINE DERIVATIVE; PROTEIN LYSINE 6 OXIDASE; SEMICARBAZIDE; UNCLASSIFIED DRUG;

ARTICLE; CORRELATION ANALYSIS; CRYSTAL; DRUG ACTIVITY; DRUG SCREENING; DRUG SELECTIVITY; ENZYME INHIBITION; ENZYME SUBSTRATE; HANSENULA POLYMORPHA; IC 50; INHIBITION KINETICS; MAMMAL; PEA; SEEDLING; STRUCTURE ANALYSIS; X RAY ANALYSIS;

ACUTE TOXICITY TESTS; AMINE OXIDASE (COPPER-CONTAINING); ANIMALS; KINETICS; LETHAL DOSE 50; MICE; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 13444287719     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0408316     Document Type: Article

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