Improved resuscitation outcome in emergency medical systems with increased usage of sodium bicarbonate during cardiopulmonary resuscitation

Acta Anaesthesiologica Scandinavica

Volumn 49, Issue 1, 2005, Pages 6-15

  Bar Joseph, Gad ^a,d,e   Abramson, N S ^a,b   Kelsey, S F ^c   Mashiach, T ^d   Craig, M T ^a   Safar, P ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^e RAMBAM MEDICAL CENTER   (Israel)

Author keywords

Acidosis; Bicarbonate; Buffer (therapy); Cardiac arrest; Cardiopulmonary resuscitation; Clinical trials; Outcome; Return of spontaneous circulation

Indexed keywords

ADRENALIN; BICARBONATE;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; EMERGENCY HEALTH SERVICE; FEMALE; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; REGRESSION ANALYSIS; RESUSCITATION; TREATMENT OUTCOME;

ACIDOSIS; AGED; BRAIN; BUFFERS; CARDIOPULMONARY RESUSCITATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EMERGENCY MEDICAL SERVICES; EPINEPHRINE; FEMALE; HEART ARREST; HUMANS; MALE; MIDDLE AGED; RANDOMIZED CONTROLLED TRIALS; SODIUM BICARBONATE; SYMPATHOMIMETICS; TACHYCARDIA, VENTRICULAR; TREATMENT OUTCOME; VENTRICULAR FIBRILLATION;

EID: 13444280497     PISSN: 00015172     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-6576.2005.00572.x     Document Type: Article

References (29)

1. Standards for Cardiopulmonary Resuscitation (CPR) and Emergency Cardiac Care (ECC). JAMA 1974; 227: 833-68.
2. Advanced Cardiac Life Support in Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care. JAMA 1992; 268: 2199-241.
3. Agents to optimize cardiac output and blood pressure in Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2000; 102/8 (Suppl): 129-35.
4. Standards and Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiac Care. JAMA 1986; 255: 2843-989.
5. Kerber RE, Sarnat W. Factors influencing the success of ventricular defibrillation in man. Circulation 1979; 60: 226-30.
6. Suljaga-Pechtel K, Goldberg E, Strickon P, Berger M, Skovron ML. Cardiopulmonary resuscitation in a hospitalized population: prospective study of factors associated with outcome. Resuscitation 1984; 12: 77-95.
7. Weil MH, Ruiz CE, Sybil M, Rackow EC. Acid-base determinants of survival after cardiopulmonary resuscitation. Crit Care Med 1985; 13 (11): 888-92.
8. Delooz HH, Lewi PJ. Are inter-center differences in EMS-management and sodium bicarbonate administration important for the outcome of CPR? The Cerebral Resuscitation Study Group. Resuscitation 1989; 17 (Suppl.): S161-72.
9. Roberts D, Landolfo K, Light RB, Dobson K. Early predictors of mortality for hospitalized patients suffering Cardiopulmonary arrest. Chest 1990; 97: 413-9.
10. Becker LB. The epidemiology of sudden death. In: Paradis NA, Halperin HG, Nowak RM, eds. Cardiac Arrest: the Science and Practice of Resuscitation Medicine. Baltimore: Williams & Wilkins, 1996; 28-47.
11. Levy RD, Rhoden WE, Shearer K, Varley E, Brooks NH. An audit of drug usage for in-hospital cardiopulmonary resuscitation. Eur Heart J 1992; 13: 1665-8.
12. Vukmir RB, Bircher NG, Radovsky A, Safar P. Sodium bicarbonate may improve outcome in dogs with brief or prolonged cardiac arrest. Crit Care Med 1995; 23: 515-22.
13. Bar-Joseph G, Weinberger T, Castel T et al. Comparison of sodium bicarbonate, Carbicarb and THAM during cardiopulmonary resuscitation in dogs. Crit Care Med 1998; 26: 1397-408.
14. Leong ECM, Bendall JC, Boyd AC, Einstein R. Sodium bicarbonate improves the chance of resuscitation after 10 minutes of cardiac arrest in dogs. Resuscitation 2001; 51: 309-15.
15. Liu X, Nozari A, Rubertsson S, Wiklund L. Buffer administration during CPR promotes cerebral perfusion after return of spontaneous circulation and mitigates post-resuscitation cerebral acidosis. Resuscitation 2002; 55: 45-55.
16. Abramson NS, Safar P, Sutton-Tyrrell K, Craig MT. for the BRCT III Study Group: a randomized clinical trial of escalating doses of high dose epinephrine during cardiac resuscitation. Crit Care Med 1995; 23: A178. [Abstract]
17. Jude JR, Kouwenhoven WB, Knickerbocker GG. Cardiac arrest - a report of application of external cardiac massage on 118 patients. JAMA 1961; 178: 1063-70.
18. Stewart JS. Management of cardiac arrest with special reference to metabolic acidosis. Br Med J 1964; 1: 476-8.
19. Weil MH, Trevino RP, Rackow EC. Sodium bicarbonate during CPR - does it help or hinder? Chest 1985; 88: 487.
20. Grundler W, Weil MH, Rackow EC. Arteriovenous carbon dioxide and pH gradients during cardiac arrest. Circulation 1986; 74: 1071-4.
21. Ayus JC, Krothapalli RK. Effect of bicarbonate administration on cardiac function. Am J Med 1989; 87: 5-6.
22. Von Planta M, Bar-Joseph G, Wiklund L, Bircher NG, Falk JL, Abramson NS. Pathophysiologic and therapeutic implications of acid-base changes during CPR. Ann Emerg Med 1993; 22 (2): 404-10.
23. Dybvik T, Strand T, Steen PA. Buffer therapy during out-of-hospital cardiopulmonary resuscitation. Resuscitation 1995; 29: 89-95.
24. van Walraven C, Stiell IG, Wells GA, Herbert PC, Vandemheen K for the OTAC Study Group. Do advanced cardiac life support drugs increase resuscitation rates from in-hospital cardiac arrests? Ann Emerg Med 1998; 32: 544-53.
25. Aufderheide TP, Martin DR, Olson DW et al. Prehospital bicarbonate use in cardiac arrest: a 3-year experience. Am J Emerg Med 1992; 10: 4-7.
26. Bar-Joseph G, Abramson NS, Jansen-McWilliams L et al. for the Brain Resuscitation Clinical Trial III Study GrouP. Clinical use of sodium bicarbonate during cardiopulmonary resuscitation - is it used sensibly? Resuscitation 2002; 54: 47-55.
27. Larsen MP, Eisenberg MS, Cummins RO, Hallstrom AP. Predicting survival from out-of-hospital cardiac arrest: a graphic model. Ann Emerg Med 1993; 22: 1652-8.
28. The Hypothermia after Cardiac Arrest Study Group. Mild therapeutic hypothermia to improve neurologic outcome after cardiac arrest. N Engl J Med 2002; 346: 549-56.
29. Bar-Joseph G. The use of acid buffers during cardiopulmonary resuscitation, a time to change again? Curr Opin Crit Care 1999; 5: 201-10.