Silencing the major apple allergen Mal d 1 by using the RNA interference approach

Journal of Allergy and Clinical Immunology

Volumn 115, Issue 2, 2005, Pages 364-369

  Gilissen, Luud J W J ^a   Bolhaar, Suzanne T H P ^b   Matos, Catarina I ^a   Rouwendal, Gerard J A ^a   Boone, Marjan J ^a   Krens, Frans A ^a   Zuidmeer, Laurian ^c   Van Leeuwen, Astrid ^c   Akkerdaas, Jaap ^c   Hoffmann Sommergruber, Karin ^d   Knulst, André C ^b   Bosch, Dirk ^a   Van De Weg, W Eric ^a   Van Ree, Ronald ^c  

^a WAGENINGEN UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c SANQUIN RESEARCH   (Netherlands)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

Apple (Malus domestica); Gene silencing; Genetic modification; Hypoallergenic; Immunoblotting; Mal d 1; RNA interference; Skin prick test

Indexed keywords

FOOD ALLERGEN; IMMUNOGLOBULIN E ANTIBODY; MONOCLONAL ANTIBODY; PROTEIN MAL D 1; UNCLASSIFIED DRUG;

ALLERGENICITY; APPLE; ARTICLE; CONTROLLED STUDY; GENE CONSTRUCT; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC CODE; GENETIC TRANSFORMATION; GROWTH RATE; HUMAN; IMMUNOBLOTTING; INTRON; INVERTED REPEAT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PLANT GROWTH; PLANT LEAF; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA INTERFERENCE; WILD TYPE;

EID: 13444267763     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2004.10.014     Document Type: Article

References (30)

1. K.E. Andersen, and H. Lowenstein An investigation of the possible immunological relationship between allergen extracts from birch pollen, hazelnut, potato and apple Contact Dermatitis 4 1978 73 79
2. N.E. Eriksson Food sensitivity reported by patients with asthma and hay fever. A relationship between food sensitivity and birch pollen-allergy and between food sensitivity and acetylsalicylic acid intolerance Allergy 33 1978 189 196
3. C. Ebner, R. Hirschwehr, L. Bauer, H. Breiteneder, R. Valenta, and K. Hoffmann-Sommergruber Identification of allergens in apple, pear, celery, carrot and potato: crossreactivity with pollen allergens Monogr Allergy 32 1996 73 77
4. A. Mari, M. Wallner, and F. Ferreira Fagales pollen sensitization in a birch-free area: a respiratory cohort survey using Fagales pollen extracts and birch recombinant allergens (rBet v 1, rBet v 2, rBet v 4) Clin Exp Allergy 33 2003 1419 1428
5. H. Breiteneder, and C. Ebner Molecular and biochemical classification of plant-derived food allergens J Allergy Clin Immunol 106 1 Pt 1 2000 27 36
6. H. Pühringer, D. Moll, K. Hoffmann-Sommergruber, B. Watillon, H. Katinger, and M.L.D. Machado The promoter of an apple Ypr10 gene, encoding the major allergen Mal d 1, is stress- and pathogen-inducible Plant Sci 152 2000 35 50
7. M. Vanek-Krebitz, K. Hoffmann-Sommergruber, M.M. Laimer da Camara, M. Susani, C. Ebner, and D. Kraft Cloning and sequencing of Mal d 1, the major allergen from apple (Malus domestica), and its immunological relationship to Bet v 1, the major birch pollen allergen Biochem Biophys Res Commun 214 1995 538 551
8. C. Ebner, R. Hirschwehr, L. Bauer, H. Breiteneder, R. Valenta, and H. Ebner Identification of allergens in fruits and vegetables: IgE cross-reactivities with the important birch pollen allergens Bet v 1 and Bet v 2 (birch profilin) J Allergy Clin Immunol 95 5 Pt 1 1995 962 969
9. C. Ebner, T. Birkner, R. Valenta, H. Rumpold, M. Breitenbach, and O. Scheiner Common epitopes of birch pollen and apples - studies by western and northern blot J Allergy Clin Immunol 88 1991 588 594
10. C. Ortolani, M. Ispano, E. Pastorello, A. Bigi, and R. Ansaloni The oral allergy syndrome Ann Allergy 61 6 Pt 2 1988 47 52
11. R. Van Ree The oral allergy syndrome S. Amin A. Lahti H.I. Maibach Contact urticaria syndrome 1997 CRC Press Boca Raton (FL) 289 299
12. S. Vieths, A. Jankiewicz, B. Schoning, and H. Aulepp Apple allergy: the IgE-binding potency of apple strains is related to the occurrence of the 18-kDa allergen Allergy 49 1994 262 271
13. L.S. Hsieh, M. Moos Jr., and Y. Lin Characterization of apple 18 and 31 kD allergens by microsequencing and evaluation of their content during storage and ripening J Allergy Clin Immunol 96 6 Pt 1 1995 960 970
14. D.Y. Son, S. Scheurer, A. Hoffmann, D. Haustein, and S. Vieths Pollen-related food allergy: cloning and immunological analysis of isoforms and mutants of Mal d 1, the major apple allergen, and Bet v 1, the major birch pollen allergen Eur J Nutr 39 1999 201 215
15. R. Nakamura, and T. Matsuda Rice allergenic protein and molecular-genetic approach for hypoallergenic rice Biosci Biotechnol Biochem 60 1996 1215 1221
16. E.M. Herman Genetically modified soybeans and food allergies J Exp Bot 54 2003 1317 1319
17. M. Kusaba RNA interference in crop plants Curr Opin Biotechnol 15 2004 139 143
18. C.F. Chuang, and E.M. Meyerowitz Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana Proc Natl Acad Sci U S A 97 2000 4985 4990
19. H.M. Pühringer, I. Zinöcker, G. Marzban, H. Katinger, and M. Laimer MdAP, a novel protein in apple, is associated with the major allergen Mal d 1 Gene 321 2003 173 183
20. A. Folck, H. Wieser, H. Lörz, and D. Becker Silencing the alpha-gliadins in wheat Book of abstracts, ISPMB 7th International Congress of Plant Molecular Biology 2003 International Society for Plant Molecular Biology Barcelona 403 (S28-28)
21. M. Byzova, C. Verduyn, D. De Brouwer, and M. De Block Transforming petals into sepaloid organs in Arabidopsis and oilseed rape: implementation of the hairpin RNA-mediated gene silencing technology in an organ-specific manner Planta 218 2004 379 387
22. T. Murashige, and F. Skoog A revised medium for rapid growth and bioassays with tobacco tissue cultures Physiol Plant 15 1962 473 497
23. F.A. Van Engelen, J.W. Molthoff, A.J. Conner, J.P. Nap, A. Pereira, and W.J. Stiekema pBINPLUS: an improved plant transformation vector based on pBIN19 Transgenic Res 4 1995 288 290
24. K.J. Puite, and J.G. Schaart Genetic modification of the commercial apple cultivars Gala, Golden Delicious and Elstar via an Agrobacterium tumefaciens-mediated transformation method Plant Sci 119 1996 125 133
25. B. Greene, R. Walko, and S. Hake Mutator insertions in an intron of the maize knotted1 gene result in dominant suppressible mutations Genetics 138 1994 1275 1285
26. S. Dreborg Allergen standardisation and skin tests. EAACI position paper Allergy 48 suppl 14 1993 49 82
27. S. Dreborg, and T. Foucard Allergy to apple, carrot and potato in children with birch pollen allergy Allergy 38 1983 167 172
28. L.K. Poulsen, C. Liisberg, C. Bindslev-Jensen, and H.J. Malling Precise area determination of skin-prick tests: validation of a scanning device and software for a personal computer Clin Exp Allergy 23 1993 61 68
29. J.H. Akkerdaas, R. Van Ree, M. Aalbers, S.O. Stapel, and R.C. Aalberse Multiplicity of cross-reactive epitopes on Bet v 1 as detected with monoclonal antibodies and human IgE Allergy 50 1995 215 220
30. L.C. Van Loon, and E.A. Van Strien The families of pathogenesis-related proteins, their activities, and comparative analysis of PR-1 type proteins Physiol Mol Plant Pathol 55 1999 85 97