-
1
-
-
0023667057
-
Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells
-
R.R. Isberg, D.L. Voorhis, and S. Falkow Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells Cell 50 1987 769 778
-
(1987)
Cell
, vol.50
, pp. 769-778
-
-
Isberg, R.R.1
Voorhis, D.L.2
Falkow, S.3
-
2
-
-
0037622178
-
Interaction of Yersinia enterocolitica with epithelial cells: Invasin beyond invasion
-
G.A. Grassl, E. Bohn, Y. Muller, O.T. Buhler, and I.B. Autenrieth Interaction of Yersinia enterocolitica with epithelial cells: invasin beyond invasion Int J Med Microbiol 293 2003 41 54
-
(2003)
Int J Med Microbiol
, vol.293
, pp. 41-54
-
-
Grassl, G.A.1
Bohn, E.2
Muller, Y.3
Buhler, O.T.4
Autenrieth, I.B.5
-
3
-
-
0035147433
-
Subversion of integrins by enteropathogenic Yersinia
-
R.R. Isberg, and P. Barnes Subversion of integrins by enteropathogenic Yersinia J Cell Sci 114 2001 21 28
-
(2001)
J Cell Sci
, vol.114
, pp. 21-28
-
-
Isberg, R.R.1
Barnes, P.2
-
4
-
-
0033920740
-
Signaling and invasin-promoted uptake via integrin receptors
-
R.R. Isberg, Z. Hamburger, and P. Dersch Signaling and invasin-promoted uptake via integrin receptors Microbes Infect 2 2000 793 801
-
(2000)
Microbes Infect
, vol.2
, pp. 793-801
-
-
Isberg, R.R.1
Hamburger, Z.2
Dersch, P.3
-
5
-
-
0034729685
-
Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex
-
Y. Luo, E.A. Frey, R.A. Pfuetzner, A.L. Creagh, D.G. Knoechel, C.A. Haynes, B.B. Finlay, and N.C. Strynadka Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex Nature 405 2000 1073 1077
-
(2000)
Nature
, vol.405
, pp. 1073-1077
-
-
Luo, Y.1
Frey, E.A.2
Pfuetzner, R.A.3
Creagh, A.L.4
Knoechel, D.G.5
Haynes, C.A.6
Finlay, B.B.7
Strynadka, N.C.8
-
6
-
-
0027158079
-
Bacterial internalization mediated by β1 chain integrins is determined by ligand affinity and receptor density
-
G. Tran Van Nhieu, and R.R. Isberg Bacterial internalization mediated by β1 chain integrins is determined by ligand affinity and receptor density EMBO J 12 1993 1887 1895
-
(1993)
EMBO J
, vol.12
, pp. 1887-1895
-
-
Tran Van Nhieu, G.1
Isberg, R.R.2
-
7
-
-
0025250067
-
Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells
-
R.R. Isberg, and J.M. Leong Multiple β1 chain integrins are receptors for invasin, a protein that promotes bacterial penetration into mammalian cells Cell 60 1990 861 871
-
(1990)
Cell
, vol.60
, pp. 861-871
-
-
Isberg, R.R.1
Leong, J.M.2
-
8
-
-
0026343041
-
The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the α5 β1 integrin receptor
-
G. Van Tran Nhieu, and R.R. Isberg The Yersinia pseudotuberculosis invasin protein and human fibronectin bind to mutually exclusive sites on the α5 β1 integrin receptor J Biol Chem 266 1991 24367 24375
-
(1991)
J Biol Chem
, vol.266
, pp. 24367-24375
-
-
Van Tran Nhieu, G.1
Isberg, R.R.2
-
9
-
-
0033536633
-
Crystal structure of invasin: A bacterial integrin-binding protein
-
Z.A. Hamburger, M.S. Brown, R.R. Isberg, and P.J. Bjorkman Crystal structure of invasin: a bacterial integrin-binding protein Science 286 1999 291 295
-
(1999)
Science
, vol.286
, pp. 291-295
-
-
Hamburger, Z.A.1
Brown, M.S.2
Isberg, R.R.3
Bjorkman, P.J.4
-
10
-
-
0033105366
-
A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association
-
P. Dersch, and R.R. Isberg A region of the Yersinia pseudotuberculosis invasin protein enhances integrin-mediated uptake into mammalian cells and promotes self-association EMBO J 18 1999 1199 1213
-
(1999)
EMBO J
, vol.18
, pp. 1199-1213
-
-
Dersch, P.1
Isberg, R.R.2
-
11
-
-
0034059454
-
An immunoglobulin superfamily-like domain unique to the Yersinia pseudotuberculosis invasin protein is required for stimulation of bacterial uptake via integrin receptors
-
P. Dersch, and R.R. Isberg An immunoglobulin superfamily-like domain unique to the Yersinia pseudotuberculosis invasin protein is required for stimulation of bacterial uptake via integrin receptors Infect Immun 68 2000 2930 2938
-
(2000)
Infect Immun
, vol.68
, pp. 2930-2938
-
-
Dersch, P.1
Isberg, R.R.2
-
12
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin αvβ3 in complex with an Arg-Gly-Asp ligand
-
J.P. Xiong, T. Stehle, R. Zhang, A. Joachimiak, M. Frech, S.L. Goodman, and M.A. Arnaout Crystal structure of the extracellular segment of integrin αVβ3 in complex with an Arg-Gly-Asp ligand Science 296 2002 151 155 This is the first report that provides the structural basis of integrin activation upon ligand binding. Unoccupied integrin adopts a highly bent, compact conformation and becomes fully extended when engaged with a ligand.
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.P.1
Stehle, T.2
Zhang, R.3
Joachimiak, A.4
Frech, M.5
Goodman, S.L.6
Arnaout, M.A.7
-
13
-
-
0141625303
-
Structure of integrin α5β1 in complex with fibronectin
-
J. Takagi, K. Strokovich, T.A. Springer, and T. Walz Structure of integrin α5β1 in complex with fibronectin EMBO J 22 2003 4607 4615
-
(2003)
EMBO J
, vol.22
, pp. 4607-4615
-
-
Takagi, J.1
Strokovich, K.2
Springer, T.A.3
Walz, T.4
-
14
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
M. Kim, C.V. Carman, and T.A. Springer Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins Science 301 2003 1720 1725
-
(2003)
Science
, vol.301
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
15
-
-
0037113091
-
The integrin β tail is required and sufficient to regulate adhesion signaling to Rac1
-
A.L. Berrier, R. Martinez, G.M. Bokoch, and S.E. LaFlamme The integrin β tail is required and sufficient to regulate adhesion signaling to Rac1 J Cell Sci 115 2002 4285 4291
-
(2002)
J Cell Sci
, vol.115
, pp. 4285-4291
-
-
Berrier, A.L.1
Martinez, R.2
Bokoch, G.M.3
Laflamme, S.E.4
-
16
-
-
0013549674
-
Mutations in the cytoplasmic domain of the integrin β1 chain indicate a role for endocytosis factors in bacterial internalization
-
G. Van Tran Nhieu, E.S. Krukonis, A.A. Reszka, A.F. Horwitz, and R.R. Isberg Mutations in the cytoplasmic domain of the integrin β1 chain indicate a role for endocytosis factors in bacterial internalization J Biol Chem 271 1996 7665 7672
-
(1996)
J Biol Chem
, vol.271
, pp. 7665-7672
-
-
Van Tran Nhieu, G.1
Krukonis, E.S.2
Reszka, A.A.3
Horwitz, A.F.4
Isberg, R.R.5
-
17
-
-
0036629339
-
Role of the β1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia
-
A. Gustavsson, A. Armulik, C. Brakebusch, R. Fassler, S. Johansson, and M. Fallman Role of the β1-integrin cytoplasmic tail in mediating invasin-promoted internalization of Yersinia J Cell Sci 115 2002 2669 2678
-
(2002)
J Cell Sci
, vol.115
, pp. 2669-2678
-
-
Gustavsson, A.1
Armulik, A.2
Brakebusch, C.3
Fassler, R.4
Johansson, S.5
Fallman, M.6
-
18
-
-
0035159257
-
Efficient uptake of Yersinia pseudotuberculosis via integrin receptors involves a Rac1-Arp 2/3 pathway that bypasses N-WASP function
-
M.A. Alrutz, A. Srivastava, K.W. Wong, C. D'Souza-Schorey, M. Tang, L.E. Ch'Ng, S.B. Snapper, and R.R. Isberg Efficient uptake of Yersinia pseudotuberculosis via integrin receptors involves a Rac1-Arp 2/3 pathway that bypasses N-WASP function Mol Microbiol 42 2001 689 703
-
(2001)
Mol Microbiol
, vol.42
, pp. 689-703
-
-
Alrutz, M.A.1
Srivastava, A.2
Wong, K.W.3
D'Souza-Schorey, C.4
Tang, M.5
Ch'Ng, L.E.6
Snapper, S.B.7
Isberg, R.R.8
-
19
-
-
0035976859
-
A role for N-WASP in invasin-promoted internalisation
-
K. McGee, M. Zettl, M. Way, and M. Fallman A role for N-WASP in invasin-promoted internalisation FEBS Lett 509 2001 59 65
-
(2001)
FEBS Lett
, vol.509
, pp. 59-65
-
-
McGee, K.1
Zettl, M.2
Way, M.3
Fallman, M.4
-
20
-
-
0034775391
-
Yersinia enterocolitica invasin triggers phagocytosis via β1 integrins, CDC42Hs and WASp in macrophages
-
A. Wiedemann, S. Linder, G. Grassl, M. Albert, I. Autenrieth, and M. Aepfelbacher Yersinia enterocolitica invasin triggers phagocytosis via β1 integrins, CDC42Hs and WASp in macrophages Cell Microbiol 3 2001 693 702
-
(2001)
Cell Microbiol
, vol.3
, pp. 693-702
-
-
Wiedemann, A.1
Linder, S.2
Grassl, G.3
Albert, M.4
Autenrieth, I.5
Aepfelbacher, M.6
-
21
-
-
0032506002
-
Involvement of focal adhesion kinase in invasin-mediated uptake
-
M.A. Alrutz, and R.R. Isberg Involvement of focal adhesion kinase in invasin-mediated uptake Proc Natl Acad Sci USA 95 1998 13658 13663
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13658-13663
-
-
Alrutz, M.A.1
Isberg, R.R.2
-
22
-
-
0036629341
-
Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake
-
P.J. Bruce-Staskal, C.L. Weidow, J.J. Gibson, and A.H. Bouton Cas, Fak and Pyk2 function in diverse signaling cascades to promote Yersinia uptake J Cell Sci 115 2002 2689 2700
-
(2002)
J Cell Sci
, vol.115
, pp. 2689-2700
-
-
Bruce-Staskal, P.J.1
Weidow, C.L.2
Gibson, J.J.3
Bouton, A.H.4
-
23
-
-
17944376439
-
CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration
-
T.L. Gumienny, E. Brugnera, A.C. Tosello-Trampont, J.M. Kinchen, L.B. Haney, K. Nishiwaki, S.F. Walk, M.E. Nemergut, I.G. Macara, and R. Francis CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration Cell 107 2001 27 41
-
(2001)
Cell
, vol.107
, pp. 27-41
-
-
Gumienny, T.L.1
Brugnera, E.2
Tosello-Trampont, A.C.3
Kinchen, J.M.4
Haney, L.B.5
Nishiwaki, K.6
Walk, S.F.7
Nemergut, M.E.8
MacAra, I.G.9
Francis, R.10
-
24
-
-
0042674398
-
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo
-
H. Katoh, and M. Negishi RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo Nature 424 2003 461 464
-
(2003)
Nature
, vol.424
, pp. 461-464
-
-
Katoh, H.1
Negishi, M.2
-
25
-
-
0035920134
-
Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathway
-
J. Gu, Y. Sumida, N. Sanzen, and K. Sekiguchi Laminin-10/11 and fibronectin differentially regulate integrin-dependent Rho and Rac activation via p130(Cas)-CrkII-DOCK180 pathway J Biol Chem 276 2001 27090 27097
-
(2001)
J Biol Chem
, vol.276
, pp. 27090-27097
-
-
Gu, J.1
Sumida, Y.2
Sanzen, N.3
Sekiguchi, K.4
-
26
-
-
0037416174
-
Differential regulation of cell motility and invasion by FAK
-
D.A. Hsia, S.K. Mitra, C.R. Hauck, D.N. Streblow, J.A. Nelson, D. Ilic, S. Huang, E. Li, G.R. Nemerow, and J. Leng Differential regulation of cell motility and invasion by FAK J Cell Biol 160 2003 753 767
-
(2003)
J Cell Biol
, vol.160
, pp. 753-767
-
-
Hsia, D.A.1
Mitra, S.K.2
Hauck, C.R.3
Streblow, D.N.4
Nelson, J.A.5
Ilic, D.6
Huang, S.7
Li, E.8
Nemerow, G.R.9
Leng, J.10
-
27
-
-
0036122427
-
Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI
-
M.A. Del Pozo, W.B. Kiosses, N.B. Alderson, N. Meller, K.M. Hahn, and M.A. Schwartz Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI Nat Cell Biol 4 2002 232 239
-
(2002)
Nat Cell Biol
, vol.4
, pp. 232-239
-
-
Del Pozo, M.A.1
Kiosses, W.B.2
Alderson, N.B.3
Meller, N.4
Hahn, K.M.5
Schwartz, M.A.6
-
28
-
-
0028081350
-
Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins
-
G.M. Bokoch, B.P. Bohl, and T.H. Chuang Guanine nucleotide exchange regulates membrane translocation of Rac/Rho GTP-binding proteins J Biol Chem 269 1994 31674 31679
-
(1994)
J Biol Chem
, vol.269
, pp. 31674-31679
-
-
Bokoch, G.M.1
Bohl, B.P.2
Chuang, T.H.3
-
29
-
-
3042839349
-
Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase
-
C. DerMardirossian, A. Schnelzer, and G.M. Bokoch Phosphorylation of RhoGDI by Pak1 mediates dissociation of Rac GTPase Mol Cell 15 2004 117 127
-
(2004)
Mol Cell
, vol.15
, pp. 117-127
-
-
Dermardirossian, C.1
Schnelzer, A.2
Bokoch, G.M.3
-
30
-
-
0034911925
-
Regulation of actin filament network formation through ARP2/3 complex: Activation by a diverse array of proteins
-
H.N. Higgs, and T.D. Pollard Regulation of actin filament network formation through ARP2/3 complex: activation by a diverse array of proteins Annu Rev Biochem 70 2001 649 676
-
(2001)
Annu Rev Biochem
, vol.70
, pp. 649-676
-
-
Higgs, H.N.1
Pollard, T.D.2
-
31
-
-
0034739859
-
Localized biphasic changes in phosphatidylinositol-4,5-bisphosphate at sites of phagocytosis
-
R.J. Botelho, M. Teruel, R. Dierckman, R. Anderson, A. Wells, J.D. York, T. Meyer, and S. Grinstein Localized biphasic changes in phosphatidylinositol-4, 5-bisphosphate at sites of phagocytosis J Cell Biol 151 2000 1353 1368
-
(2000)
J Cell Biol
, vol.151
, pp. 1353-1368
-
-
Botelho, R.J.1
Teruel, M.2
Dierckman, R.3
Anderson, R.4
Wells, A.5
York, J.D.6
Meyer, T.7
Grinstein, S.8
-
32
-
-
0038603841
-
Membrane ruffling requires coordination between type Iα phosphatidylinositol phosphate kinase and Rac signaling
-
R.L. Doughman, A.J. Firestone, M.L. Wojtasiak, M.W. Bunce, and R.A. Anderson Membrane ruffling requires coordination between type Iα phosphatidylinositol phosphate kinase and Rac signaling J Biol Chem 278 2003 23036 23045
-
(2003)
J Biol Chem
, vol.278
, pp. 23036-23045
-
-
Doughman, R.L.1
Firestone, A.J.2
Wojtasiak, M.L.3
Bunce, M.W.4
Anderson, R.A.5
-
33
-
-
0042422047
-
Arf6 and phosphoinositol-4-phosphate-5-kinase activities permit bypass of the Rac1 requirement for β1 integrin-mediated bacterial uptake
-
2 as the components of a pathway that links Rac1-dependent signals to invasin-mediated uptake.
-
(2003)
J Exp Med
, vol.198
, pp. 603-614
-
-
Wong, K.W.1
Isberg, R.R.2
-
34
-
-
0034628109
-
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
-
K.F. Tolias, J.H. Hartwig, H. Ishihara, Y. Shibasaki, L.C. Cantley, and C.L. Carpenter Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly Curr Biol 10 2000 153 156
-
(2000)
Curr Biol
, vol.10
, pp. 153-156
-
-
Tolias, K.F.1
Hartwig, J.H.2
Ishihara, H.3
Shibasaki, Y.4
Cantley, L.C.5
Carpenter, C.L.6
-
35
-
-
1542319943
-
Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42
-
P.A. Weernink, K. Meletiadis, S. Hommeltenberg, M. Hinz, H. Ishihara, M. Schmidt, and K.H. Jakobs Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42 J Biol Chem 279 2004 7840 7849
-
(2004)
J Biol Chem
, vol.279
, pp. 7840-7849
-
-
Weernink, P.A.1
Meletiadis, K.2
Hommeltenberg, S.3
Hinz, M.4
Ishihara, H.5
Schmidt, M.6
Jakobs, K.H.7
-
36
-
-
4043115604
-
Lamellipodial versus filopodial mode of the actin nanomachinery: Pivotal role of the filament barbed end
-
M.R. Mejillano, S. Kojima, D.A. Applewhite, F.B. Gertler, T.M. Svitkina, and G.G. Borisy Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end Cell 118 2004 363 373
-
(2004)
Cell
, vol.118
, pp. 363-373
-
-
Mejillano, M.R.1
Kojima, S.2
Applewhite, D.A.3
Gertler, F.B.4
Svitkina, T.M.5
Borisy, G.G.6
-
37
-
-
1842430006
-
Bacterial invasion: The paradigms of interoinvasive pathogens
-
P. Cossart, and P.J. Sansonetti Bacterial invasion: the paradigms of interoinvasive pathogens Science 304 2004 242 248
-
(2004)
Science
, vol.304
, pp. 242-248
-
-
Cossart, P.1
Sansonetti, P.J.2
-
38
-
-
2942667797
-
Requirement for the Rac GTPase in Chlamydia trachomatis invasion of non-phagocytic cells
-
R.A. Carabeo, S.S. Grieshaber, A. Hasenkrug, C. Dooley, and T. Hackstadt Requirement for the Rac GTPase in Chlamydia trachomatis invasion of non-phagocytic cells Traffic 5 2004 418 425
-
(2004)
Traffic
, vol.5
, pp. 418-425
-
-
Carabeo, R.A.1
Grieshaber, S.S.2
Hasenkrug, A.3
Dooley, C.4
Hackstadt, T.5
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