The immunodetection of lipoprotein-bound amyloid-β is attenuated because of the presence of lipids

Annals of Clinical Biochemistry

Volumn 42, Issue 1, 2005, Pages 70-72

  James, A P ^a   Mamo, John C L ^a  

^a CURTIN UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; DIMER; EPITOPE; LIPID; LIPOPROTEIN; MONOMER;

AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; CEREBROSPINAL FLUID LEVEL; CONCENTRATION (PARAMETERS); EMULSION; IMMUNODETECTION; IMMUNOREACTIVITY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN CONFORMATION; PROTEIN PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; SOLUBILIZATION;

AMYLOID BETA-PROTEIN; HUMANS; IMMUNOBLOTTING; LIPID METABOLISM; LIPOPROTEINS;

EID: 13444259386     PISSN: 00045632     EISSN: None     Source Type: Journal    
DOI: 10.1258/0004563053026826     Document Type: Article

References (5)

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2. Koudinov AR, Koudinova NV, Kumar A, Beavis RC, Ghiso J. Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: association with high density lipoproteins. Biochem Biophys Res Commun 1996; 223: 592-7
3. James AP, Pal S, Gennat HC, Vine DF, Mamo JC. The incorporation and metabolism of amyloid-beta into chylomicron-like lipid emulsions. J Alzheimer's Dis 2003; 5: 179-88
4. Yanagisawa K, McLaurin J, Michikawa M, Chakrabartty A, Ihara Y. Amyloid beta-protein (A beta) associated with lipid molecules: immunoreactivity distinct from that of soluble A beta. FEBS Lett 1997; 420: 43-6
5. Mamo JC, Elsegood CL, Umeda Y, Hirano T, Redgrave TG. Effect of probucol on plasma clearance and organ uptake of chylomicrons and VLDLs in normal and diabetic rats. Arterioscler Thromb 1993; 13: 231-9