Epstein-Barr virus-associated peripheral T-cell lymphoma and hemophagocytic syndrome arising after liver transplantation: Case report and review of the literature

Pediatric Blood and Cancer

Volumn 44, Issue 3, 2005, Pages 270-276

  George, Tracy I ^a,b   Jeng, Michael ^a   Berquist, William ^a   Cherry, Athena M ^a   Link, Michael P ^a   Arber, Daniel A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Epstein Barr virus (EBV); Hemophagocytic syndrome; Peripheral T cell lymphoma; Post transplant lymphoproliferative disorder (PTLD)

Indexed keywords

AMPHOTERICIN B; CYTOMEGALOVIRUS ANTIBODY; DEXAMETHASONE; ETOPOSIDE; GANCICLOVIR; TACROLIMUS; VORICONAZOLE;

ANTIBODY BLOOD LEVEL; ANTIBODY TITER; ASPERGILLUS; BLOOD SAMPLING; BONE MARROW BIOPSY; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CASE REPORT; COLON; COMPUTER ASSISTED TOMOGRAPHY; CYTOMEGALOVIRUS INFECTION; EPSTEIN BARR VIRUS; ERYTHROCYTE TRANSFUSION; HEMODIALYSIS; HEMOPHAGOCYTIC SYNDROME; HERPES; HUMAN; INFORMATION RETRIEVAL; KIDNEY FAILURE; LIVER FAILURE; LIVER GRAFT; LIVER GRAFT REJECTION; LUNG ABSCESS; LUNG NODULE; LYMPHADENOPATHY; MALE; MYCOSIS; PANCYTOPENIA; PERIPHERAL T CELL LYMPHOMA; POLYMERASE CHAIN REACTION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RADIOLOGY; RECURRENT DISEASE; REVIEW; SCHOOL CHILD; SPLENOMEGALY; STOMACH ANTRUM; THROMBOCYTE TRANSFUSION; ULTRASOUND;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; EPSTEIN-BARR VIRUS INFECTIONS; FEMALE; HERPESVIRUS 4, HUMAN; HISTIOCYTOSIS, NON-LANGERHANS-CELL; HUMANS; IMMUNOPHENOTYPING; LIVER TRANSPLANTATION; LYMPHOMA, T-CELL, PERIPHERAL; MALE; MIDDLE AGED; POSTOPERATIVE COMPLICATIONS;

EID: 13444259326     PISSN: 15455009     EISSN: None     Source Type: Journal    
DOI: 10.1002/pbc.20231     Document Type: Review

References (38)

1. Leblond V, Sutton L, Dorent R, et al. Lymphoproliferative disorders after organ transplantation: A report of 24 cases observed in a single center. J Clin Oncol 1995;13:961-968.
2. Dharnidharka VR, Tejani AH, Ho PL, et al. Post-transplant lymphoproliferative disorder in the United States: Young Caucasian males are at highest risk. Am J Transplant 2002;2:993-998.
3. Smets F, Latinne D, Bazin H, et al. Ratio between Epstein-Barr viral load and anti-Epstein-Barr virus specific T-cell response as a predictive marker of post transplant lymphoproliferative disease. Transplantation 2002;73:1603-1610.
4. Jain A, Nalesnik M, Reyes J, et al. Posttransplant lymphoproliferative disorders in liver transplantation: A 20-year experience. Ann Surg 2002;236:429-437.
5. Penn I. Tumors after renal and cardiac transplantation. Hematol Oncol Clin North Am 1993;7:431-445.
6. Sivaraman P, Lye WC. Epstein-Barr virus-associated T-cell lymphoma in solid organ transplant recipients. Biomed Pharmacother 2001;55:366-368.
7. Dockrell DH, Strickler JG, Paya CV. Epstein-Barr virus-induced T cell lymphoma in solid organ transplant recipients. Clin Infect Dis 1998;26:180-182.
8. Imashuku S, Kurtiyama K, Teramura T, et al. Requirement for etoposide in the treatment of Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. J Clin Oncol 2001;19:2665-2673.
9. Srivastava T, Zwick DL, Rothberg PG, et al. Post transplant lymphoproliferative disorder in pediatric renal transplantation. Pediatr Nephrol 1999;13:748-754.
10. Friedrichs C, Neyts J, Gaspar G, et al. Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay. Antiviral Research 2004;62:121-123.
11. Roulston D, Le Beau MM. Hematological malignant disease. In: Barch MJ, Knutsen T, Spurbeck JL, editors. The AGT cytogenetics laboratory manual. Philadelphia: Lippencott-Raven Publications; 1997. pp 351-359.
12. Higgins JP, van de Rijn M, Jones CD, et al. Peripheral T-cell lymphoma complicated by a proliferation of large B cells. Am J Clin Pathol 2000;114:236-247.
13. Kogawa K, Lee SM, Villaneueva J, et al. Perform expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members. Blood 2002;99:61-66.
14. Kaplan MA, Jacobson JO, Ferry JA, et al. T-cell lymphoma of the vulva in a renal allograft recipient with associated hemophagocytosis. Am J Surg Pathol 1993;17:842-849.
15. Imashuku S, Hibi S, Ohara T, et al. Effective control of Epstein-Barr virus-related hemophagocytic lymphohistiocytosis with immunochemotherapy. Blood 1999;93:1869-1874.
16. Quintanilla-Martinez L, Kumar S, Fend F, et al. Fulminant EBV+ T-cell lymphoproliferative disorder following acute/chronic EBV infection: A distinct clinicopathologic syndrome. Blood 2000;96:443-451.
17. Hanson MN, Morrison VA, Peterson BA, et al. Post transplant T-cell lymphoproliferative disorders - An aggressive, late complication of solid-organ transplantation. Blood 1996;88:3626-3633.
18. Wu TT, Swerdlow SH, Locker J, et al. Recurrent Epstein-Barr virus-associated lesions in organ transplant recipients. Hum Pathol 1996;27:157-164.
19. Waller EK, Ziemianska M, Bangs CD, et al. Characterization of posttransplant lymphomas that express T-cell-associated markers: Immunophenotypes, molecular genetics, cytogenetics, and heterotransplantation in severe combined immunodeficient mice. Blood 1993;82:247-261.
20. Lundell R, Elenitoba-Johnson KSJ, Lim MS. T-cell post transplant lymphoproliferative disorder occurring in a pediatric solid-organ transplant patient. Am J Surg Pathol 2004;28:967-973.
21. Penn I. Why do immunosuppressed patients develop cancer? In: Pimentel E, editor. CRC critical reviews in oncogenesis. Boca Raton: CRC; 1989. 27p.
22. Borisch B, Hennig I, Horber F, et al. Enteropathy-associated T-cell lymphoma in a renal transplant patient with evidence of Epstein-Barr virus involvement. Virchows Arch A Pathol Anat Histopathol 1992;421:443-447.
23. Frias C, Lauzurica R, Vaquero M, et al. Detection of Epstein-Barr virus in post transplantation T cell lymphoma in a kidney transplant recipient: Case report and review. Clin Infect Dis 2000;30:576-578.
24. Harris NL, Ferry JA, Swerdlow SH. Post transplant lymphoproliferative disorders: Summary of society for hematopathology workshop. Semin Diagn Pathol 1997;14:8-14.
25. Hoshida Y, Li T, Dong Z, et al. Lymphoproliferative disorders in renal transplant patients in Japan. Int J Cancer 2001;91:869-875.
26. Kumar S, Kumar D, Kingma DW, et al. Epstein-Barr virus-associated T-cell lymphoma in a renal transplant patient. Am J Surg Pathol 1993;17:1046-1053.
27. Lye WC. Successful treatment of Epstein-Barr virus-associated T-cell cutaneous lymphoma in a renal allograft recipient: Case report and review of the literature. Transplant Proc 2000;32:1988-1989.
28. Mandel L, Surattanont F, Dourmas M. T-cell lymphoma in the parotid region after cardiac transplant: Case report. J Oral Maxillofac Surg 2001;59:673-677.
29. Roncella S, Cutrona G, Truini M, et al. Late Epstein-Barr virus infection of a hepatosplenic gamma delta T-cell lymphoma arising in a kidney transplant recipient. Haematologica 2000;85:256-262.
30. Yasunaga C, Kasai T, Nishihara G, et al. Early development of Epstein-Barr virus-associated T-cell lymphoma after a living-related renal transplantation. Transplantation 1998;65:1642-1644.
31. Yufu Y, Kimura M, Kawano R, et al. Epstein-Barr virus-associated T cell lymphoproliferative disorder following autologous blood stem cell transplantation for relapsed Hodgkin's disease. Bone Marrow Transplant 2000;26:1339-1341.
32. Melosky B, Karim M, Chui A, et al. Lymphoproliferative disorders after renal transplantation in patients receiving triple or quadruple immunosuppression. J Am Soc Nephrol 1992;2:S290-S294.
33. Lin WC, Moore JO, Mann KP, et al. Post transplant CD8+ gammadelta T-cell lymphoma associated with human herpes virus-6 infection. Leuk Lymphoma 1999;33:377-384.
34. Rickinson AB, Kieff E. Epstein-Barr virus. In: Knipe DM, Howley PM, editors. Fields virology. Philadelphia: Lippincott, Williams and Raven; 2001. pp 2575-2627.
35. Young L, Alfieri C, Hennessy K, et al. Expression of Epstein-Barr virus transformation-associated genes in tissues of patients with EBV lymphoproliferative disease. N Engl J Med 1989;321:1080-1085.
36. Arber DA, Shibata D, Chen YY, et al. Characterization of the topography of Epstein-Barr virus infection in human immunodeficiency virus-associated lymphoid tissues. Mod Pathol 1992;5:559-566.
37. Fischer E, Delibrias C, Kazatchkine MD. Expression of CR2 (the C3dg/EBV receptor, CD21) on normal human peripheral blood T lymphocytes. J Immunol 1991;146:865-869.
38. Chuhjo T, Yachie A, Kanegane H, et al. Epstein-Barr virus (EBV)-associated post-transplantation lymphoproliferative disorder simultaneously affecting both B and T cells after allogeneic bone marrow transplantation. Am J Hematol 2003;72:255-258.