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Volumn 33, Issue 1, 2005, Pages 84-89

Effect of carboxylesterase inhibition on the anti-tumour effects of irinotecan

Author keywords

Bis p nitrophenylphosphate; Carboxylesterase; HT 29 xenograft mouse; Irinotecan (CPT 11); Pro drug

Indexed keywords

4 NITROPHENYL PHOSPHATE; CARBOXYLESTERASE; ENZYME INHIBITOR; IRINOTECAN;

EID: 13444254412     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000503300108     Document Type: Article
Times cited : (10)

References (12)
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    • Iyer L, King CD, Whitington PF, Green MD, Roy SK, Tephly TR, et al: Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. J Clin Invest 1998; 101: 847-854.
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  • 2
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    • Multiplicity of carboxylesterase isozymes in mammals and humans: Role in metabolic activation of prodrugs
    • (in Japanese)
    • Hosokawa M, Watanabe N, Tsukada E, Fukumoto M, Ogasawara Y, Daimon M, et al: Multiplicity of carboxylesterase isozymes in mammals and humans: role in metabolic activation of prodrugs (in Japanese). Yakubutsudoutai 2001; 16: 92-93.
    • (2001) Yakubutsudoutai , vol.16 , pp. 92-93
    • Hosokawa, M.1    Watanabe, N.2    Tsukada, E.3    Fukumoto, M.4    Ogasawara, Y.5    Daimon, M.6
  • 3
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    • Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2
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    • Humerickhouse, R.1    Lohrbach, K.2    Li, L.3    Bosron, W.F.4    Dolan, M.E.5
  • 4
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    • Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans
    • Hosokawa M, Maki T, Satoh T: Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans. Arch Biochem Biophys 1990; 227: 219-227.
    • (1990) Arch. Biochem. Biophys. , vol.227 , pp. 219-227
    • Hosokawa, M.1    Maki, T.2    Satoh, T.3
  • 5
    • 0028364014 scopus 로고
    • Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1 piperidino] carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase
    • Satoh T, Hosokawa M, Atsumi R, Suzuki W, Hakusui H, Nagai E: Metabolic activation of CPT-11, 7-ethyl-10-[4-(1-piperidino)-1 piperidino] carbonyloxycamptothecin, a novel antitumor agent, by carboxylesterase. Biol Pharm Bull 1994; 17: 662-664.
    • (1994) Biol. Pharm. Bull. , vol.17 , pp. 662-664
    • Satoh, T.1    Hosokawa, M.2    Atsumi, R.3    Suzuki, W.4    Hakusui, H.5    Nagai, E.6
  • 8
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    • CPT-11 in human colon-cancer cell lines and xenografts: Characterization of cellular sensitivity determinants
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    • (1997) Int. J. Cancer , vol.70 , pp. 335-340
    • Jansen, W.J.M.1    Zwart, B.2    Hulscher, S.T.M.3    Giaccone, G.4    Pinedo, H.M.5    Boven, E.6
  • 10
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    • Human plasma carboxylesterase and butyrylcholinesterase enzyme activity: Correlations with SN-38 pharmacokinetics during a prolonged infusion of irinotecan
    • Guemei AA, Cottrell J, Bond R, Hehman H, Prudhomme M, Pavlov MV, et al: Human plasma carboxylesterase and butyrylcholinesterase enzyme activity: correlations with SN-38 pharmacokinetics during a prolonged infusion of irinotecan. Cancer Chemother Pharmacol 2001; 47: 283-290.
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  • 11
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.