The Role of β-Glucuronidase in Induction of Apoptosis by Genistein Combined Polysaccharide (GCP) in Xenogeneic Mice Bearing Human Mammary Cancer Cells

Annals of the New York Academy of Sciences

Volumn 1010, Issue , 2003, Pages 347-349

  Yuan, Lan ^a   Wagatsuma, Chihiro ^a   Sun, Buxiang ^a   Kim, Jung Hwan ^b   Surh, Young Joon ^b  

^a Amino Up Chemical Co   (Japan)

^b Seoul National University   (South Korea)

Author keywords

Apoptosis; Genistein combined polysaccharide (GCP); Tumor; glucuronidase

Indexed keywords

BETA GLUCURONIDASE; GENISTEIN; POLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; BREAST CANCER; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; DRUG METABOLISM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUDE MOUSE;

ANIMALIA; MUS MUSCULUS;

EID: 1342347870     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1299.063     Document Type: Conference Paper

References (3)

1. MIURA, T. et al. 2001. Development of a natural antitimor substance GCP™. New Food Industry 43: 17-22.
2. MIURA, T. et al. 2002. Isoflavone aglycon produced by culture of soybean extracts with basidiomycetes and its anti-angiogenic activity. Biosci. Biotechnol. Biochem. 66: 2626-2631.
3. YUAN, L. et al. 2003. Inhibition of human breast cancer growth by GCP™ (genistein combined polyscccharide) in xenogeneic athymic mice: involvement of genistein biotransformation by beta-glucuronidase from tumor tissues. Mutat. Res. 523-524: 55-62.