Development and validation method for determination of Paroxetine and its metabolites by nonaqueous capillary electrophoresis in human urine. Experimental design for evaluating the ruggedness of the method

Electrophoresis

Volumn 25, Issue 3, 2004, Pages 454-462

  Rodríguez Flores, Juana ^a   Barzas Nevado, Juan J ^a   Contento Salcedo, Ana M ^a   Cabello Díaz, Maria P ^a  

^a Dept of Analyt Chem/Foods Tech ^*  (Spain)

Author keywords

Antidepressant; Human urine; Nonaqueous capillary electrophoresis

Indexed keywords

BIOMOLECULES; CAPILLARY ELECTROPHORESIS; DISEASES; METHANOL;

AMMONIUM ACETATE; ANTIDEPRESSANT; BUFFER SYSTEM; DISEASE TREATMENT; HUMAN URINE; MENTAL DISEASE; NON-AQUEOUS; NON-AQUEOUS CAPILLARY ELECTROPHORESIS; PAROXETINE; SIMPLE++;

METABOLITES;

ACETIC ACID; ACETONITRILE; AMMONIUM ACETATE; ANTIDEPRESSANT AGENT; BUFFER; DRUG METABOLITE; FLUOXETINE; METHANOL; PAROXETINE;

ACCURACY; ANALYTIC METHOD; ARTICLE; CAPILLARY ELECTROPHORESIS; CONCENTRATION PROCESS; CONTROLLED STUDY; DRUG URINE LEVEL; ELECTRIC POTENTIAL; ELUTION; EXPERIMENTAL DESIGN; EXTRACTION; HUMAN; HYDRODYNAMICS; LINEAR SYSTEM; MENTAL DISEASE; MOLECULAR STABILITY; NONAQUEOUS PHASE LIQUID; SENSITIVITY AND SPECIFICITY; STANDARD; STATISTICAL MODEL; TEMPERATURE; URINALYSIS; VALIDATION PROCESS;

EID: 1342347328     PISSN: 01730835     EISSN: None     Source Type: Journal    
DOI: 10.1002/elps.200305686     Document Type: Article

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