Is C-Reactive Protein an Inflammation Opsonin that Signals Colon Cancer Risk?

JAMA

Volumn 291, Issue 5, 2004, Pages 623-624

  Pasche, Boris ^a   Serhan, Charles N ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; C REACTIVE PROTEIN; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; ICOSANOID; NONSTEROID ANTIINFLAMMATORY AGENT; OPSONIN; SULINDAC; IMMUNOGLOBULIN RECEPTOR; OPSONIN RECEPTOR;

CANCER RISK; COLON CANCER; DRUG EFFECT; DRUG MECHANISM; EDITORIAL; HUMAN; IMMUNE SYSTEM; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; RECTUM CANCER; RISK FACTOR; BLOOD; COLORECTAL TUMOR; METABOLISM; NOTE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; C-REACTIVE PROTEIN; COLORECTAL NEOPLASMS; HUMANS; INFLAMMATION; RECEPTORS, IMMUNOLOGIC; RISK FACTORS;

EID: 1342331311     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.291.5.623     Document Type: Editorial

References (21)

1. Munkholm P. Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease. Aliment Pharmacol Ther. 2003;18(suppl 2):1-5.
2. Baron JA, Sandler RS. Nonsteroidal anti-inflammatory drugs and cancer prevention. Annu Rev Med. 2000;51:511-523.
3. Sandler RS, Halabi S, Baron JA, et al. A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. N Engl J Med. 2003;348:883-890.
4. Baron JA, Cole BF, Sandler RS, et al. A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med. 2003;348:891-899.
5. Erlinger TP, Platz EA, Rifai N, Helzisouer KJ. C-reactive protein and the risk of incident colorectal cancer. JAMA. 2004;291:585-590.
6. Tillett WS, Francis T. Serological reactions in pneumonia with a non-protein somatic fraction of pneumococcus. J Exp Med. 1930;52:561-571.
7. McCarty M. Historical perspective on C-reactive protein. Ann N Y Acad Sci. 1982;389:1-10.
8. Kushner I. The phenomenon of the acute phase response. Ann N Y Acad Sci. 1982;389:39-48.
9. General effects of local injury and inflammation. In: Majno G, Joris I, eds. Cells, Tissues, and Disease: Principles of General Pathology. Cambridge, England: Blackwell Science; 1996:487-494.
10. Tumors as parasites. In: Majno G, Joris I, eds. Cells, Tissues, and Disease: Principles of General Pathology. Cambridge, England: Blackwell Science; 1996:779-816.
11. Claria J, Serhan CN. Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions. Proc Natl Acad Sci U S A. 1995;92:9475-9479.
12. Serhan CN, Oliw E. Unorthodox routes to prostanoid formation: new twists in cyclooxygenase-initiated pathways. J Clin Invest. 2001;107:1481-1489.
13. Wallace JL, Fiorucci S. A magic bullet for mucosal protection and aspirin is the trigger! Trends Pharmacol Sci. 2003;24:323-326.
14. Steinbach G, Lynch PM, Phillips RK, et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Engl J Med. 2000;342:1946-1952.
15. Cruz-Correa M, Hylind LM, Romans KE, Booker SV, Giardiello FM. Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study. Gastroenterology. 2002;122:641-645.
16. Vane JR. The mechanism of action of anti-inflammatory drugs. Ernst Schering Res Found Workshop. 2000;(31):1-23.
17. FitzGerald GA. COX-2 and beyond: approaches to prostaglandin inhibition in human disease. Nat Rev Drug. Discov. 2003;2:879-890.
18. Title LM, Giddens K, McInerney MM, et al. Effect of cyclooxygenase-2 inhibition with rofecoxib on endothelial dysfunction and inflammatory markers in patients with coronary artery disease. J Am Coll Cardiol. 2003;42:1747-1753.
19. Marnett LJ, Dubois RN. COX-2: a target for colon cancer prevention. Annu Rev Pharmacol Toxicol. 2002;42:55-80.
20. Macintyre SS, Schultz D, Kushner I. Biosynthesis of C-reactive protein. Ann N Y Acad Sci. 1982;389:76-87.
21. Venugopal SK, Devaraj S, Jialal I. C-reactive protein decreases prostacyclin release from human aortic endothelial cells. Circulation. 2003;108:1676-1678.