Heck-Type Arylation of 2-Cycloalken-1-ones with Arylpalladium Intermediates Formed by Decarboxylative Palladation and by Aryl Iodide Insertion

Organic Letters

Volumn 6, Issue 3, 2004, Pages 433-436

  Tanaka, Daisuke ^a   Myers, Andrew G ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYL GROUP; CYCLOALKENE; IODINE DERIVATIVE; KETONE DERIVATIVE; PALLADIUM; PHOSPHINE DERIVATIVE;

ARTICLE; ARYLATION; CATALYSIS; DECARBOXYLATION; HECK REACTION;

EID: 1342327964     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol0363467     Document Type: Article

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30. 4; the dried solution was filtered, and the filtrate was concentrated. Purification of the residue by flash column chromatography afforded the 3-aryl-2-cycloalken-1-one product, typically in 50-90% yield.
31. Structure 3 is believed to be the (E)-stereoisomer, as shown. This assignment is based upon one-dimensional NOESY experiments.
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