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Volumn 5143, Issue , 2003, Pages 181-192

Two channel fluorescence lifetime microscope with two colour laser excitation, single molecule sensitivity and sub-micrometer resolution

Author keywords

Confocal microscopy; Fluorescence correlation spectroscopy (FCS); Fluorescence lifetime imaging (FLIM); Picosecond diode laser; Single molecule detection; Time correlated single photon counting (TCSPC); Time tagged time resolved data acquisition (TTTR)

Indexed keywords

DIAGNOSIS; FLUORESCENCE; LASER APPLICATIONS; MEDICAL IMAGING; MOLECULES; OPTICAL DEVICES; PHOTONS;

EID: 1342326418     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.500610     Document Type: Conference Paper
Times cited : (19)

References (25)
  • 2
    • 0027736716 scopus 로고
    • Ultrasensitive detection of single molecules in flowing sample streams by laser-induced fluorescence
    • P.M. Goodwin, C.W. Wilkerson Jr, W.P. Ambrose and R.A. Keller, "Ultrasensitive detection of single molecules in flowing sample streams by laser-induced fluorescence", Proc SPIE 1895, pp. 79-89, 1993.
    • (1993) Proc SPIE , vol.1895 , pp. 79-89
    • Goodwin, P.M.1    Wilkerson Jr., C.W.2    Ambrose, W.P.3    Keller, R.A.4
  • 3
    • 0028320267 scopus 로고
    • Analysis of fluorescence lifetime data for single rhodamine molecules in flowing sample streams
    • J. Tellinghuisen, P.M. Goodwin, W.P. Ambrose, J.C. Martin and R.A. Keller, "Analysis of Fluorescence Lifetime Data for Single Rhodamine Molecules in Flowing Sample Streams", Anal. Chem. 66, pp. 64-72, 1994.
    • (1994) Anal. Chem. , vol.66 , pp. 64-72
    • Tellinghuisen, J.1    Goodwin, P.M.2    Ambrose, W.P.3    Martin, J.C.4    Keller, R.A.5
  • 6
    • 1342277174 scopus 로고
    • High-speed electronics for fast detection of time-resolved fluorescence in single molecule experiments
    • R. Erdmann, J. Enderlein, W. Becker, M. Wahl, "High-Speed Electronics for Fast Detection of Time-Resolved Fluorescence in Single Molecule Experiments". Exp.Tech. Phys., 41, No. 2, pp. 189-193, 1995.
    • (1995) Exp. Tech. Phys. , vol.41 , Issue.2 , pp. 189-193
    • Erdmann, R.1    Enderlein, J.2    Becker, W.3    Wahl, M.4
  • 7
    • 0003315616 scopus 로고
    • TIMEHARP - A time measurement Histogram accumulating realtime processor
    • Eurochip, U.K.
    • G. Kell and H.-J. Rahn, "TIMEHARP - A Time Measurement Histogram Accumulating Realtime Processor" Poster, EURO-DAC'95/EURO-VHDL'95, Eurochip, U.K., 1995.
    • (1995) EURO-DAC'95/EURO-VHDL'95
    • Kell, G.1    Rahn, H.-J.2
  • 8
    • 0001243008 scopus 로고    scopus 로고
    • An all solid-state near-infrared time-correlated single photon counting instrument for dynamic lifetime measurements in DNA sequencing applications
    • B.L. Legendre, D.C. Williams, S.A. Soper, R. Erdmann, U. Ortmann and J. Enderlein, "An all solid-state near-infrared time-correlated single photon counting instrument for dynamic lifetime measurements in DNA sequencing applications", Rev Sci. Instrum. 67 (11), pp. 3984-3989, 1996.
    • (1996) Rev Sci. Instrum. , vol.67 , Issue.11 , pp. 3984-3989
    • Legendre, B.L.1    Williams, D.C.2    Soper, S.A.3    Erdmann, R.4    Ortmann, U.5    Enderlein, J.6
  • 9
    • 0029707274 scopus 로고    scopus 로고
    • High-speed electronics for the detection of time-resolved fluorescence in a continuous flow system
    • R. Erdmann, U. Ortmann, J. Enderlein, W. Becker, M. Wahl and E.O. Klose, "High-speed electronics for the detection of time-resolved fluorescence in a continuous flow system", Proc. SPIE 2680, pp. 176-81, 1996.
    • (1996) Proc. SPIE , vol.2680 , pp. 176-181
    • Erdmann, R.1    Ortmann, U.2    Enderlein, J.3    Becker, W.4    Wahl, M.5    Klose, E.O.6
  • 10
    • 0031591239 scopus 로고    scopus 로고
    • A maximum likelihood estimator to distinguish single molecules by their fluorescence decays
    • J. Enderlein, P.M. Goodwin, A. Van Orden, W.P. Ambrose, R. Erdmann and R.A. Keller, "A maximum likelihood estimator to distinguish single molecules by their fluorescence decays", Chem. Phys. Lett. 270 (5-6), pp. 464-70, 1997.
    • (1997) Chem. Phys. Lett. , vol.270 , Issue.5-6 , pp. 464-470
    • Enderlein, J.1    Goodwin, P.M.2    Van Orden, A.3    Ambrose, W.P.4    Erdmann, R.5    Keller, R.A.6
  • 12
    • 0032225337 scopus 로고    scopus 로고
    • Hardware solution for continuous time-resolved burst detection of single molecules in flow
    • M. Wahl, R. Erdmann, K. Lauritsen, H.-J. Rahn, "Hardware solution for continuous time-resolved burst detection of single molecules in flow" Proc. SPIE 3259, pp.173-178, 1998.
    • (1998) Proc. SPIE , vol.3259 , pp. 173-178
    • Wahl, M.1    Erdmann, R.2    Lauritsen, K.3    Rahn, H.-J.4
  • 13
    • 0001041265 scopus 로고    scopus 로고
    • Simple near-infrared time-correlated single photon counting instrument with a pulsed diode laser and avalanche photodiode (APD) for time-resolved measurements in scanning applications
    • Y. Zhang, S.A. Soper, L.R. Middendorf, J.A. Wurm, R. Erdmann, and M. Wahl, Simple Near-Infrared Time-Correlated Single Photon Counting Instrument with a Pulsed Diode Laser and Avalanche Photodiode (APD) for Time-Resolved Measurements in Scanning Applications. Applied Spectroscopy, 53, Number 5, pp. 497-504, 1999.
    • (1999) Applied Spectroscopy , vol.53 , Issue.5 , pp. 497-504
    • Zhang, Y.1    Soper, S.A.2    Middendorf, L.R.3    Wurm, J.A.4    Erdmann, R.5    Wahl, M.6
  • 14
    • 0001013570 scopus 로고    scopus 로고
    • Identification of single fluorescently labelled mononucleotide molecules in solution by spectrally resolved time-correlated single-photon counting
    • D.P. Herten, P. Tinnefeld, M. Sauer, "Identification of single fluorescently labelled mononucleotide molecules in solution by spectrally resolved time-correlated single-photon counting", Applied Physics B, 71, pp. 765-771, 2000.
    • (2000) Applied Physics B , vol.71 , pp. 765-771
    • Herten, D.P.1    Tinnefeld, P.2    Sauer, M.3
  • 15
    • 0035878236 scopus 로고    scopus 로고
    • Fluorescence lifetime imaging with near-field scanning optical microscopy
    • E.-S. Kwak, T. J. Kang, D.A. Vanden Bout, "Fluorescence lifetime imaging with near-field scanning optical microscopy", Analytical Chemistry, 73, pp. 3257-3262, 2001.
    • (2001) Analytical Chemistry , vol.73 , pp. 3257-3262
    • Kwak, E.-S.1    Kang, T.J.2    Vanden Bout, D.A.3
  • 16
    • 0035975486 scopus 로고    scopus 로고
    • Photophysical dynamics of single molecules studied by spectrally-resolved fluorescence lifetime imaging microscopy (SFLIM)
    • P. Tinnefeld, D.-P. Herten, M. Sauer "Photophysical dynamics of single molecules studied by spectrally-resolved fluorescence lifetime imaging microscopy (SFLIM)" J.Phys.Chem. A, 105, pp. 7989-8003, 2001.
    • (2001) J. Phys. Chem. A , vol.105 , pp. 7989-8003
    • Tinnefeld, P.1    Herten, D.-P.2    Sauer, M.3
  • 19
    • 0008458526 scopus 로고    scopus 로고
    • Single molecule detection on surfaces with the confocal laser scanning microscope single molecule detection in solution
    • Eds.: Zander Ch., Enderlein J., Keller R. A., ISBN 3-527-40310-8, Wiley-VCH
    • M. Böhmer, J. Enderlein, "Single molecule detection on surfaces with the confocal laser scanning microscope Single molecule detection in solution" Eds.: Zander Ch., Enderlein J., Keller R. A., ISBN 3-527-40310-8, Wiley-VCH, pp. 145-183, 2002.
    • (2002) , pp. 145-183
    • Böhmer, M.1    Enderlein, J.2
  • 23
    • 1342298226 scopus 로고    scopus 로고
    • www.picoquant.com
  • 24
    • 9344266550 scopus 로고    scopus 로고
    • Application of laser diodes and ultrabright light emitting diodes for static and time-resolved optical methods in physical chemistry
    • Editors: H. S. Nalwa, L. S. Rohwer, ISBN: 1-58883-010-1, American Scientific Publishers
    • S. Landgraf, "Application of laser diodes and ultrabright light emitting diodes for static and time-resolved optical methods in physical chemistry", Handbook of Luminescence, Display Materials and Devices. 1-3, Editors: H. S. Nalwa, L. S. Rohwer, ISBN: 1-58883-010-1, American Scientific Publishers, 2003.
    • (2003) Handbook of Luminescence, Display Materials and Devices , vol.1-3
    • Landgraf, S.1
  • 25
    • 0037436845 scopus 로고    scopus 로고
    • Controlled non-classical photon emission from single conjugated polymer molecules
    • C.W. Hollars, S.M. Lane, T. Huser, "Controlled non-classical photon emission from single conjugated polymer molecules", Chem. Phys. Lett., 370, pp. 393-398, 2003.
    • (2003) Chem. Phys. Lett. , vol.370 , pp. 393-398
    • Hollars, C.W.1    Lane, S.M.2    Huser, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.