Synthesis and evaluation of new arylsulfonamidomethylcyclohexyl derivatives as human neuropeptide Y Y 5 receptor antagonists for the treatment of obesity

European Journal of Medicinal Chemistry

Volumn 39, Issue 1, 2004, Pages 49-58

  Moreno, Antonio ^a   Pérez, Silvia ^a   Galiano, Silvia ^a   Juanenea, Laura ^a   Erviti, Oihana ^a   Frígola, Carmen ^a   Aldana, Ignacio ^a   Monge, Antonio ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Arylsulfonamide; H NPY Y5 antagonists; NPY; Obesity

Indexed keywords

4 (SULFONYLAMINOMETHYL)CYCLOHEXANECARBOXYLIC ACID; AMIDE; N [4 (3 BENZYL 1 PHENYLUREIDOMETHYL)CYCLOHEXYLMETHYL]BENZENESULFONAMIDE; N [4 (PHENYLAMINOCARBONYL)CYCLOHEXYLMETHYL]BENZENESULFONAMIDE; N [4 (PHENYLAMINOMETHYL)CYCLOHEXYLMETHYL]BENZENESULFONAMIDE; N [4 [(N FORMYL N PHENYLAMINO)METHYL]CYCLOHEXYLMETHYL]BENZENESULFONAMIDE; N [4 [(QUINOLIN 3 YL)AMINOCARBONYL]CYCLOHEXYLMETHYL] 2,4 DICHLOROBENZENESULFONAMIDE; NEUROPEPTIDE Y RECEPTOR ANTAGONIST; NEUROPEPTIDE Y5 RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; OBESITY; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 1342321921     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2003.10.001     Document Type: Article

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