Upregulation and Formation of SDS-Resistant Oligomers of the Proapoptotic Factor Bax in Experimental Atherosclerosis

Annals of the New York Academy of Sciences

Volumn 1010, Issue , 2003, Pages 738-741

  Seye, Cheikh I ^a   De Meyer, Guido Ry ^a   Martinet, Wim ^a   Knaapen, Michiel W M ^b   Bult, Hidde ^a   Herman, Arnold G ^a   Kockx, Mark M ^a,c  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b HistoGeneX NV   (Belgium)

^c MIDDELHEIM HOSPITAL   (Belgium)

Author keywords

Apoptosis; Atherosclerosis; Bax oligomerization; Plaque destabilization; Smooth muscle cells

Indexed keywords

CHOLESTEROL; CYTOCHROME C OXIDASE; MESSENGER RNA; OLIGOMER; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN BAX; TRIFLUOROACETIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; APOPTOSIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL DEATH; CHOLESTEROL BLOOD LEVEL; CONFERENCE PAPER; CONTROLLED STUDY; HYPERCHOLESTEROLEMIA; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LOW FAT DIET; NONHUMAN; OLIGOMERIZATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; STATISTICAL SIGNIFICANCE; UPREGULATION; WESTERN BLOTTING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 1342305434     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1299.133     Document Type: Conference Paper

References (4)

1. GENG, Y.-J. & P. LIBBY. 2002. Progression of atheroma. A struggle between death and procreation. Arterioscler. Thromb. Vasc. Biol. 22: 1370-1380.
2. KOCKX, M.M., G.R.Y. DE MEYER, N. BUYSSENS, et al. 1998. Cell composition, replication and apoptosis in atherosclerotic plaques after 6 months of cholesterol withdrawal. Circ. Res. 83: 378-387.
3. SAGNÉ, C., M.-F. ISAMBERT, J.P. HENRY & B. GASNIER. 1996. SDS-resistant aggregation of membrane proteins: application to the purification of the vesicular monoamine transporter. Biochem. J. 316: 825-831.
4. ESKES, R., S. DESAGHER, B. ANTONSSON & J.-C. MARTINOU. 2000. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Mol. Cell. Biol. 20: 929-935.