Prognostic factors and therapeutic problems of primary intracranial choriocarcinoma/germ-cell tumors with high levels of HCG: A review with the description of three new patients

Journal of Neuro-Oncology

Volumn 66, Issue 1-2, 2004, Pages 225-240

  Shinoda, Jun ^a   Sakai, Noboru ^a   Yano, Hirohito ^a   Hattori, Tatsuaki ^b   Ohkuma, Akio ^b   Sakaguchi, Heima ^a  

^a GIFU UNIVERSITY   (Japan)

^b GIFU PREFECTURAL GIFU HOSPITAL   (Japan)

Author keywords

Human chorionic gonadotropin; Intracranial germ cell tumor; Primary intracranial choriocarcinoma; Prognostic factor

Indexed keywords

ANTINEOPLASTIC AGENT; CARBOPLATIN; CHORIONIC GONADOTROPIN; CHORIONIC GONADOTROPIN BETA SUBUNIT; CISPLATIN; ETOPOSIDE;

ADOLESCENT; ADULT; AGE; ARTICLE; BRAIN SURGERY; BRAIN VENTRICLE PERITONEUM SHUNT; CANCER COMBINATION CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CHORIOCARCINOMA; CONTROLLED STUDY; DRUG MEGADOSE; FEMALE; FOLLOW UP; GERM CELL TUMOR; GONADOTROPIN BLOOD LEVEL; HISTOPATHOLOGY; HUMAN; INTRACRANIAL TUMOR; LUNG EMBOLISM; LUNG METASTASIS; MAJOR CLINICAL STUDY; MALE; METASTASIS; MIXED TUMOR; MULTIVARIATE ANALYSIS; PRECOCIOUS PUBERTY; PREOPERATIVE TREATMENT; PRESCHOOL CHILD; PROGNOSIS; SEX; SURVIVAL RATE; TUMOR BIOPSY; TUMOR BLEEDING; TUMOR LOCALIZATION;

ADOLESCENT; ADULT; BRAIN NEOPLASMS; CHILD; CHORIOCARCINOMA; CHORIONIC GONADOTROPIN; GERMINOMA; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; PROGNOSIS; SURVIVAL ANALYSIS;

EID: 1342287136     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:NEON.0000013499.74404.81     Document Type: Article

References (82)

1. Askanazy M: Die Teratom und Chorioepitheliom der Zirbel. Verh Dtsch Ges Pathol 10: 58-76, 1906
2. Giuffrè R, Lorenzo ND: Evolution of a primary intrasellar germinomatous teratoma into a choriocarcinoma. Case report. J Neurosurg 42: 602-604, 1975
3. Romshe CA, Sotos J: Intracranial human chorionic gonadotropin-secreting tumor with precocious puberty. J Pediatr 86: 250-252, 1975
4. Hirano T, Kawai K, Tsuchiyama H: An autopsy case of HCG secreting intracranial teratoma. Acta Pathol Jpn 26: 97-103, 1976
5. Ishii R, Tsuchida T, Honda H, Ueki K, Oyake Y: Radiation therapy and surgical management of pineal tumors - Follow-up study of 96 patients. No Shinkei Geka 4: 263-270, 1976
6. Taomoto K, Tamaki N, Obora Y, Nakai Y, Sato H, Asada M, Matsumoto S, Yoshimoto Y, Imura H: Intracranial human chorionic gonadotropin producing tumors - Its endocrinological and pathological findings. Neurol Med Chir 16: 411-418, 1976
7. Ohashi T, Miyake I, Shimamura Y, Harada Y, Ohmoto T, Nishimoto A, Takahara J: A long survival case of primary pineal chorioepithelioma with pubertas praecox. No Shinkei Geka 5: 1377-1383, 1977
8. Shin KH, Freeman CR, Stachwitsch A: Primary intracranial mixed choriocarcinoma and malignant teratoma. J Can Assoc Radiol 29: 129-131, 1978
9. Tominaga I, Nishikawa K, Kawakami H, Kato Y, Matsuyama H, Kameya T: HCG proved by enzyme-labeled antibody technique in a suprasellar tumor. An autopsy case report. No To Shinkei 30: 165-169, 1978
10. Weir B, MacDonald N, Mielke B: Intracranial vascular complications of choriocarcinoma. Neurosurgery 2: 138-142, 1978
11. Allen JC, Nisselbaum J, Epstein F, Rosen G, Schwartz MK: Alphafetoprotein and human chorionic gonadotropin determination in cerebrospinal fluid. An aid to the diagnosis and management of intracranial germ-cell tumors. J Neurosurg 51: 368-374, 1979
12. Arita N, Ushio Y, Hayakawa T, Watanabe M, Maeda Y, Kanai N, Mogami H: Primary intracranial germ cell tumor. No Shinkei Geka 7: 465-474, 1979
13. Esteban HM, Dillanueva JP, Bueno JG, Puentes MF: Primary intracranial choriocarcinoma. Surg Neurol 11: 21-23, 1979
14. Haase J, Nielsen K: Value of tumor markers in the treatment of endodermal sinus tumors and choriocarcinomas in the pineal region. Neurosurgery 5: 485-488, 1979
15. Rao CVGK, Govindan S: Intracranial choriocarcinoma. J Comput Assist Tomogr 3: 400-404, 1979
16. Kawakami Y, Yamada O, Tabuchi K, Ohmoto T, Nishimoto A: Primary intracranial choriocarcinoma. J Neurosurg 53: 369-374, 1980
17. Fujii T, Itakura T, Hayashi S, Komai N, Nakamine H, Saito K: Primary pineal choriocarcinoma with hemorrhage monitored by computerized tomography. J Neurosurg 55: 484-487, 1981
18. Wass JAH, Jones AE, Rees LH, Besser GM: hCGβ producing pineal choriocarcinoma. Clin Endocrinol 17: 423-431, 1982
19. Moriyama T, Teramoto S, Kitajima H, Yonekawa M, Nakamura M, Matsumura H: Primary intracranial germ cell tumor in the right basal ganglia and its vicinity area - A report of the case with germinoma and choriocarcinoma histologically. No Shinkei Geka 11: 73-80, 1983
20. Sato N, Sato H, Nakagawa Y, Kataoka K, Hojo H, Tamaki N, Matsumoto S: Primary intracranial choriocarcinoma causing hemorrhage. Case report. Neurol Med Chir 23: 896-901, 1983
21. Shinmura F, Takayasu K, Sakata R, Ariwa R, Takagi S: An autopsy case of extra-neural metastasis of suprasellar choriocarcinoma. Jpn J Cancer Clin Cancer 29: 832-837, 1983
22. Yamagami T, Handa H, Takeuchi J, Niijima K, Furukawa F: Choriocarcinoma arising from the pituitary fossa with extracranial metastasis: A review of the literature. Surg Neurol 19: 469-480, 1983
23. Chan HSL, Humphreys RP, Hendrick EB, Chuang SH, Fitz CR, Becker LE: Primary intracranial choriocarcinoma: A report of two cases and a review of the literature. Neurosurgery 15: 540-545, 1984
24. Naganuma H, Inoue H, Misumi S, Nakamura M, Tamura M: Intracranial germ-cell tumors. Immunohistochemical study of three autopsy cases. J Neurosurg 61: 931-937, 1984
25. Blümel P, Grümayer ER, Machacek E, Stögmann W: β-HCG-produzierendes Choriokarzinom der Pinealisregion als Ursache einer Pubertas praecox. Helv Paediatr Acta 40: 473-479, 1985
26. Kida Y, Banno M, Kanzaki M, Kobayashi T, Kageyama N: Pineal choriocarcinoma presenting massive ventricular hemorrhage. No Shinkei Geka 13: 641-645, 1985
27. Bjornsson J, Scheithauer BW, Leech RW: Primary intracranial choriocarcinoma: A case report. Clin Neuropathol 5: 242-245, 1986
28. Kubota T, Itoh T: A case report of primary intracranial choriocarcinoma. Kanagawa Igakkai Zasshi 13: 446, 1986
29. Ono N, Inoue HK, Naganuma H, Misumi S, Tamura M: Germ cell tumor in the basal ganglia: Immunohistochemical demonstration of α-fetoprotein, human chorionic gonadotropin, and carcinoembryonic antigen. Surg Neurol 25: 495-500, 1986
30. Graziano SL, Paolozzi FP, Rudolph AR, Stewart WA, Elbadawi A, Comis RL: Mixed germ-cell tumor of the pineal region. Case report. J Neurosurg 66: 300-304, 1987
31. Page R, Doshi B, Sharr MM: Primary intracranial choriocarcinoma. J Neurol Neurosurg Psychiatry 49: 93-95, 1986
32. Koyama S, Tsubokawa T, Katayama Y, Hirota H: Choriocarcinoma of the septum pellucidum: Case report. Surg Neurol 35: 478-482, 1991
33. Chen MN, Nakazawa S, Hori M: A case of primary intracranial choriocarcinoma with a carotid-cavernous fistula. No Shinkei Geka 21: 1031-1034, 1993
34. Massie RJ, Shaw PJ, Burgess M: Intracranial choriocarcinoma causing precocious puberty and cured with combined modality therapy. J Paediatr Child Health 29: 464-467, 1993
35. Herrmann HD, Westphal M, Winkler K, Laas RW, Schulte FJ: Treatment of nongerminomatous germ-cell tumors of the pineal region. Neurosurgery 34: 524-529, 1994
36. Miyagami M, Kasahara E, Tsubokawa T: Clinical features and treatment of malignant germ cell tumors. Nerv Syst Child 19: 41-48, 1994
37. Kitanaka C, Matsutani M, Sora S, Kitanaka S, Tanae A, Hibi I: Precocious puberty in a girl with an hCG-secreting suprasellar immature teratoma. Case report. J Neurosurg 81: 601-604, 1994
38. Kimura H, Miyashita Y, Inoue K, Ogawa H, Kasayama M, Koga M, Sato B, Kishimoto C, Nakahara K, Arita N: A case report of successfully treated HCG-secreting primary intracranial choriocarcinoma by high dose chemotherapy with autologous bone marrow transplantation. Nippon Naika Gakkai Zasshi 84: 132-134, 1995
39. Prall JA, McGavran L, Greffe BS, Partington MD: Intracranial malignant germ cell tumor and the Klinefelter syndrome. Pediatr Neurosurg 23: 219-224, 1995
40. Nitta H, Yamashita J, Nomura M, Igarashi N: Cervical spinal cord infarction after surgery for a pineal region choriocarcinoma in the sitting position: Case report. Neurosurgery 40: 1082-1086, 1997
41. Nam DH, Cho BK, Shin HJ, Ahn HS, Kim IH, Wang KC: Treatment of intracranial nongerminomatous malignant germ cell tumor in children: The role of each treatment modality. Childs Nerv Syst 15: 185-191, 1999
42. Tada T, Takizawa T, Nakazato F, Kobayashi S, Koike K, Oguchi M, Ishii E, Amano Y: Treatment of intracranial nongerminomatous germ-cell tumor by high-dose chemotherapy and autologous stem-cell rescue. J Neuro-Oncol 44: 71-76, 1999
43. Marx M, Beck JD, Grabenbauer GG, Fahlbusch R, Dörr HG: Gonadotropin-independent puberty in a boy with a β-HCG-secreting brain tumour. Horm Res 54: 44-48, 2000
44. Sakurada K, Kayama T, Kawakami K, Saino M, Sato S: A successfully operated case of choriocarcinoma with recurrent intratumoral hemorrhage. No Shinkei Geka 28: 67-72, 2000
45. Kohyama S, Uematsu M, Ishihara S, Shima K, Tamai S, Kusano S: An experience of stereotactic radiation therapy for primary intracranial choriocarcinoma. Tumori 87: 162-165, 2001
46. Kubo O, Yamasaki N, Kamijo Y, Amayo K, Kitamura K: Human chorionic gonadotropin produced by ectopic pinealoma in a girl with precocious puberty. Case report. J Neurosurg 47: 101-105, 1977
47. The Committee of Brain Tumor Registry of Japan: Report of Brain Tumor Registry of Japan (1969-1993) 10th edn. Neurol Med Chir 40(Suppl): 9-10, 2000
48. Jennings MT, Gelman R, Hochberg F: Intracranial germcell tumors: Natural history and pathogenesis. J Neurosurg 63: 155-167, 1985
49. Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, Seto T: Primary intracranial germ cell tumors: A clinical analysis of 153 histologically verified cases. J Neurosurg 86: 446-455, 1997
50. Rogers PB, Sims EC, Plowman N: Blood to cerebrospinal fluid human chorionic gonadotropin-beta ratios in intracranial germ cell tumors. Neurosurg Focus 5: Article 4, 1998
51. Matsutani M, Ushio Y, Abe H, Yamashita J, Shibui S, Fujimaki T, Takakura K, Nomura K, Tanaka R, Fukui M, Yoshimoto T, Hayakawa T, Nagashima T, Kurisu K, Kayama T, Japanese Pediatric Brain Tumor Study Group: Combined chemotherapy and radiation therapy for central nervous system germ cell tumors: Preliminary results of a Phase II study of the Japanese Pediatric Brain Tumor Study Group. Neurosurg Focus 5: Article 7, 1998
52. Goldzieher M: Über eine Zirbeldrüsengeschwulst. Virchows Arch 213: 353-365, 1913
53. Van Hasselt JA: Tumor glandular pinealis, sive epiphysis cerebri. Ned Tijdschr Geneeskd 1: 1271-1287, 1913
54. Ohno S: Epiphysenteratom. Acta Med Fukuoka 8: 1-26, 1914
55. Nakamura H: Supplementary report of the study of endocrinological pathology. Trans Soc Pathol Jpn 12: 461-468, 1927
56. Wirth W: Über sexuelle Frühreife. Ztschr Ges Anat 15: 47-91, 1931
57. Gerstley JR, Kasanin J, Lovenhaupt E: Teratoma of the pineal body. J Pediatr 17: 512-520, 1940
58. Davidoff LM: Endocrinologic aspects of tumors of pineal gland. Surgery 16: 306-314, 1944
59. Russell DS: The pinealoma: Its relationship to teratoma. J Pathol Bact 56: 145-150, 1944
60. Stowell RE, Sachs E, Russell WO: Primary intracranial chorioepithelioma with metastasis to the lungs. Am J Pathol 21: 787-800, 1945
61. Glass RL, Culbertson CG: Teratoma of pineal gland with choriocarcinoma and rhabdomyosarcoma. Arch Pathol 41: 552-555, 1946
62. McGovern VJ: Tumours of the epiphysis cerebri. J Pathol Bact 61: 1-9, 1946
63. Zondek H, Kaatz A, Unger H: Precocious puberty and chorioepithelioma of the pineal gland with report of a case. J Endocrinol 10: 12-16, 1953
64. Nishizuka Y, Morii S, Ojima A, Takeuchi I, Akazawa Y: Three autopsy cases of testicular and intracranial choriocarcinoma in the male. Acta Pathol Jpn 6: 841-849, 1956.
65. Araki C, Fukushima K: Tumors of the diencephalon and pubertas praecox. Saishin Igaku 12: 224-236, 1957
66. Bruton OC, Martz DC, Gerard ES: Precocious puberty due to secreting chorioepithelioma (teratoma) of the brain. J Pediatr 59: 719-725, 1961
67. Iwata K, Nakajima N, Nakajima M, Sato N: Report of a case of pineal tumors with extensive metastasis into lung. No To Shinkei 14: 815-818, 1962
68. Kageyama N: Pubertas praecox. Jpn J Clin Med 20: 132-144, 1962
69. Edmonds LC, Carrera GM: Extragenital choriocarcinoma. J Pediatr 67: 94-98, 1965
70. Nishiyama RH, Batsakins JG, Weaver DK, Simrall JH: Germinal neoplasms of the central nervous system. Arch Surg 93: 342-347, 1966
71. Hutchinson JSM, Brooks RV, Barratt TM, Newmann CGH: Sexual precosity due to an intracranial tumour causing unusual testicular secretion of testosterone. Arch Dis Child 44: 732-737, 1969
72. Musiani P, Mancuso S: Coriocarcinoma primitivo intracranico originato da tumore germinale sellare in una bambina in eta prepubere. Arch Ital Anat Istol Patol 43: 61-75, 1969
73. Jellinger K, Minauf M, Kraus H, Sunder-Plassmann M: Embryonales carcinom der epiphysenregion. Acta Neuropathol 14: 176-182, 1970
74. Hori S, Sakurai Y, Shinko K, Kaku R: Germinal tumor in pineal gland. Rinsho Shinkeigaku 11: 106, 1971
75. Komatsu K, Hiratsuka H, Inaba Y: Clinical and pathological studies on pineal tumors. Bull Tokyo Med Dent Univ 18: 137-147, 1971
76. Mori K, Fujita Y, Moritake K, Handa H, Hazanna F; Intracranial tumor with precocious puberty - Analysis of histologic nature and location of 16 cases in our clinic. No To Shinkei 23: 1185-1191, 1971
77. Abe H, Abe K, Tsuganesawa M: An autopsy case of intracranial teratoid tumor with metastasis to the lungs. Iryo 26: 49-52, 1972
78. Shibata S, Yamaguchi T, Hongo H, Kawano M: Case report of primary intracranial malignant tumor with extracranial metastasis. J Jpn Soc Surg 73: 80, 1972
79. Tabuchi K, Tanigawa M, Babe Y, Nishimoto A: Primary intracranial choriocarcinoma in the pineal region. A case report and review of the literature. Acta Med Okayama 27: 125-132, 1973
80. Jellinger K: Primary intracranial germ cell tumours. Acta Neuropathol 25: 291-306, 1973
81. Hasegawa H, Ushio Y, Hori M, Kanai N, Ikeda T, Uozumi T, Mogami H: Primary intracranial choriocarcinoma in the pineal region. A case report. Med J Osaka Univ 25: 63-71, 1974
82. Mori K, Iwayama K, Fujita Y: Malignant suprasellar teratoma in a girl with elevated serum gonadotropin: Case report and some considerations for development of precocious puberty. No Shinkei Geka 2: 243-248, 1974