Novel long-chain acyl-derivative of epigallocatechin-3-O-gallate prepared and purified from green tea polyphenols

Journal of Zhejiang University: Science

Volumn 4, Issue 6, 2003, Pages 714-718

  Chen, Ping ^a   Tan, Yao ^a   Sun, Dong ^b   Zheng, Xiao Ming ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Epigallocatechin 3 O gallate; Epigallocatechin 3 O gallate 4 O hexadecanate; Green tea polyphenols; High speed countercurrent chromatography; Isolation; Lipophilic tea polyphenols

Indexed keywords

CATALYSIS; ESTERIFICATION; LIQUID CHROMATOGRAPHY; MOLECULAR STRUCTURE; PURIFICATION;

EPIGALLOCATECHIN-3-O-GALLATE; GREEN TEA POLYPHENOLS; HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY; ISOLATION; LIPOPHILIC TEA POLYPHENOLS; LONG CHAIN ACYL DERIVATIVE;

BIOMATERIALS;

CATECHIN; CHLORINATED HYDROCARBON; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; FLAVONOID; PHENOL DERIVATIVE; POLYPHENOLS;

ACYLATION; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROPHOTOMETRY; ISOLATION AND PURIFICATION; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; TEA;

ACYLATION; CATECHIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTERIFICATION; FLAVONOIDS; HYDROCARBONS, CHLORINATED; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENOLS; SPECTROPHOTOMETRY, INFRARED; TEA;

EID: 1342284378     PISSN: 10093095     EISSN: None     Source Type: Journal    
DOI: 10.1631/jzus.2003.0714     Document Type: Article

References (11)

1. Dreosti, I.E., 1996. Bioactive ingredients: antioxidants and polyphenols in tea. Nutr. Rev., 54(11): S51-S58.
2. Hollman, P.C.H., Feskens, E.J.M. and Katan, M.B., 1999. Tea flavonols in cardiovascular disease and cancer epidemiology. Proc . Soc. Exp. Biol. Med., 220: 198-202.
3. Ito, Y. and Conway, W. D.(Editors), 1996. High-Speed Countercurrent Chromatography. Wiley-Interscience, New York.
4. Jia, Z. S., Zhou, B., Yang, L., Wu, L. M . and Liu, Z. L., 1998. 2D NMR study on tea polyphenols. Chin. J. Mag. Resonance, 15(1): 23-30 (in Chinese).
5. Johnson, M. K. and Loo, G., 2000. Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA. Mutat. Res., 459: 211-218.
6. Li, H. C., Yashiki, S., Sonoda, J., Lou, H., Ghosh, S. K., Byrnes, J. J., Lema, C., Fujiyoshi, T., Karasuyama, M. and Sonoda, S., 2000. Green tea polyphenols induce apoptosis in vitro in peripheral blood T lymphocytes of adult T-cell leukemia patients. Jpn. J. Cancer. Res., 91: 34-40.
7. Liang, Y., Shen, S.R., Yang, X.Q., Zhao, B.L. and Hou, J.W., 1999. Antioxidant properties of lipophilic tea polyphenols. J. Zhejiang University (Agric. and Life Sci.), 25(5): 529-534 (in Chinese).
8. Oka, F., Oka, H. and Ito, Y., 1991. Systematic search for suitable two-phase solvent systems for high-speed counter-current chromatography. J. Chromatogr., 538 (1): 99-108.
9. Wang, Q.E., Tang, A.B., Ma, Z.H., Huang, W. and Shi, B., 2002. Synthesis of liposoluble tea polyphenols with varying aliphatic groups and their antioxidation activity. Chin. Fine Chemicals, 19(2): 86-89 (in Chinese).
10. Zhong, J.H., Chen, P., Zhang, G.Y., Wang, L.S. and Qian, J., 1999. A method of esterification production for lipophilic tea polyphenols. CN 1231277A (in Chinese).
11. Zhu, N., Wang, M., Wei, G.J., Lin, J.K., Yang, C. S. and Ho, C.T., 2001. Identification of reaction products of (-)-epigallocatechin, (-)-epigallocatechin gallate and pyrogallol with 2, 2-diphenyl-l-picrylhydrazyl radical. Food Chemistry, 73: 345-349.