Differential effects of sodium selenite in reducing tissue damage caused by three hemoglobin-based oxygen carriers

Journal of Applied Physiology

Volumn 96, Issue 3, 2004, Pages 893-903

  Baldwin, Ann L ^a   Wiley, Elizabeth B ^a   Aiayash, Abdu I ^b  

^a UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Intestinal mucosal epithelium; Mast cell degranulation; Rat mesentery

Indexed keywords

ALBUMIN; BLOOD SUBSTITUTE; DIASPIRIN CROSSLINKED HEMOGLOBIN; FLUORESCEIN ISOTHIOCYANATE; HEME; HEMOGLOBIN; OXIDIZING AGENT; OXYGLOBIN; POLYMERIZED HEMOGLOBIN; SODIUM SELENITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING SITE; BLOOD VESSEL INJURY; CONTROLLED STUDY; HISTOPATHOLOGY; IN VITRO STUDY; INTESTINE EPITHELIUM; MALE; MAST CELL DEGRANULATION; MEMBRANE STRUCTURE; MESENTERIC VEIN; MICROSCOPY; MICROVASCULATURE; MOLECULAR INTERACTION; NONHUMAN; OXIDATION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; OXYGEN AFFINITY; PERFUSION; PRIORITY JOURNAL; PROTEIN MODIFICATION; RAT; RAT STRAIN; TISSUE INJURY;

ANIMALS; BLOOD SUBSTITUTES; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; HEMOGLOBINS; HUMANS; INTESTINAL MUCOSA; MALE; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM SELENITE;

EID: 1342283038     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00615.2003     Document Type: Article

References (37)

1. Alayash AI. Hemoglobin-based blood substitutes: oxygen carriers, pressor agents, or oxidants? Nat Biotechnol 17: 545-549, 1999.
2. Alayash AI, Summers AG, Wood F, and Jia Y. Effects of glutaraldehyde polymerization on oxygen transport and redox properties of bovine hemoglobin. Arch Biochem Biophys 391: 225-234, 2001.
3. Aziz ES and Kiesius PH. Depressed neutrophil chemotactic stimuli in supernatants of ionophore-treated polymorphonuclear leukocytes from selenium-deficient goats. Am J Vet Res 47: 140-152, 1986.
4. Aziz ES, Klesius PH, and Frandsen JC. Effects of selenium on polymorphonuclear leukocyte function in goats. Am J Vet Res 45: 1715-1718, 1984.
5. Baldwin AL. Blood substitutes and the intestinal microcirculation: extravasation and ultrastructural alterations. In: Advances in Blood Substitutes: Industrial Opportunities and Medical Challenges, edited by Winslow RM, Vandergriff KD, and Intaglietta M. Boston, MA: Birkhauser, 1997, p. 19-37.
6. Baldwin AL. Modified hemoglobins produce venular interendothelial gaps and albumin leakage in the rat mesentery. Am J Physiol Heart Circ Physiol 277: H650-H659, 1999.
7. Baldwin AL and Thurston G. Changes in endothelial actin cytoskeleton in venules with time after histamine treatment. Am J Physiol Heart Circ Physiol 269: H1528-H1537, 1995.
8. Baldwin AL and Wiley EB. Selenium reduces hemoglobin-induced damage to intestinal mucosa. Artif Cells Blood Substit Immobil Biotechnol 30: 1-22, 2002.
9. Baldwin AL, Wiley EB, and Alayash AI. Comparison of effects of two hemoglobin-based oxygen carriers on intestinal integrity and microvascular leakage. Am J Physiol Heart Circ Physiol 283: H1292-H1301, 2002.
10. Baldwin AL, Wiley EB, Summers AG, and Alayash AI. Sodium selenite reduces hemoglobin-induced venular leakage in the rat mesentery. Am J Physiol Heart Circ Physiol 284: H81-H91, 2003.
11. Baldwin AL, Wilson LM, and Valeski JE. Ultrastructural effects of intravascularly injected polyethylene glycol-hemoglobin in intestinal mucosa. Am J Physiol Heart Circ Physiol 275: H615-H625, 1998.
12. Blum J and Fridovich I. Inactivation of glutathione peroxidase by superoxide radical. Arch Biochem Biophys 240: 500-508, 1985.
13. Buettner GR. The pecking order of free radicals and antioxidants: lipid peroxidation, α-tocopherol, and ascorbate. Arch Biochem Biophys 300: 535-543, 1993.
14. Carr AC and Winterbourne CC. Oxidation of neutrophil glutathione and protein thiols by myeloperoxidase-derived hypochlorous acid. Biochem J 327: 275-281, 1997.
15. Chen CY and Lin TH. Effects of selenium dioxide on blood and femoral bone marrow of rats. J Toxicol Environ Health 59: 553-560, 2000.
16. D'Agnillo F and Alayash AI. Site-specific modifications and toxicity of blood substitutes. The case of diaspirin cross-linked hemoglobin. Adv Drug Delivery Res 40: 199-212, 2000.
17. D'Agnillo F and Alayash AI. Redox cycling of diaspirin cross-linked hemoglobin induces G2/M arrest and apoptosis in cultured endothelial cells. Blood 98: 3315-3323, 2002.
18. Forstrom JW, Zakowski JJ, and Tappel AL. Identification of the catalytic site of rat liver glutathione péroxidase as selenocysteine. Biochemistry 17: 2639-2644, 1978.
19. Hayashi A, Suzuki T, and Shin M. An enzymic reduction system for metmyoglobin and methemoglobin, and its application to functional studies of oxygen carriers. Biochim Biophys Acta 310: 309-316, 1973.
20. Hess JR. Blood substitutes for surgery and trauma: efficacy and toxicity issues. BioDrug 12: 81-90, 1999.
21. Levy A, Kuppusamy P, and Rifkind JM. Multiple heme pocket subconformations of metHb associated with distal histidine interactions. Biochemistry 29: 9311-9316, 1990.
22. Milici AJ and Bankston PW. Fetal and neonatal rat intestinal capillaries: permeability to carbon, ferritin, hemoglobin, and myoglobin. Am J Anat 165: 165-186, 1982.
23. Nagababu E, Somasundaram R, and Rifkind JM. Site-specific cross-linking of human and bovine hemoglobins differentially alters oxygen binding and redox side reactions producing rhombic heme and heme degradation. Biochemistry 41: 7407-7415, 2002.
24. Nyberg-Swenson BE. The selenium link: the missing link in our understanding of biochemical trigger reactions? Med Hypotheses 52: 125-131, 1999.
25. Pearce BL and Gawryl MS. Overview of preclinical and clinical efficacy of Biopure's HBOCs. In: Blood Substitutes: Principles, Methods, Products and Clinical Trials, edited by Chang TMS. Basel, Switzerland: Karger Landes Systems, 1998, vol. II, p. 82-100.
26. Rosenblat M and Aviran M. Macrophage glutathione content and glutathione peroxidase activity are inversely related to cell-mediated oxidation of LDL: in vitro and in vivo studies. Free Radic Biol Med 24: 305-317, 1998.
27. Seko Y, Saito Y, Kitihara J, and Imura N. Active oxygen generation by the reaction of selenite with reduced glutathione in vitro. In: Selenium in Biology and Medicine, edited by Wendel A. New York: Springer-Verlag, p. 70-73, 1989.
28. Simoni J, Simoni G, Garcia EL, Prien SD, Tran RM, Feola M, and Shires GT. Protective effect of selenium on hemoglobin mediated lipid peroxidation in vivo. Artif Cells Blood Substit Immobil Biotechnol 23: 469-486 1995.
29. Sloan ER, Koenigsberg M, Gens D, Cipolle M, Runge J, Mullory M, and Rodman G. Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhage shock: a randomized controlled efficacy trial. JAMA 282: 1857-1864, 1999.
30. Tappel AL. Glutathione peroxidase and its seleno-cysteine active sites. In: Selenium in Biology and Medicine, edited by Spallholz JE, Martin JL, and Ganther HE. Westport, CT: Avi Publishing, 1981, p. 44-53.
31. Thurston G and Baldwin AL. Endothelial actin cytoskeleton in rat mesentery microvasculature. Am J Physiol Heart Circ Physiol 266: H1896-H1909, 1994.
32. Whanger PD. Metabolism of pyruvate, succinate and glutamate by tissues from selenium-responsive myopathic lambs. Biochem Med 7: 316-322, 1973.
33. Wilson LM and Baldwin AL. Environmental stress causes mast cell degranulation, endothelial and epithelial changes, and edema in the rat intestinal mucosa. Microcirculation 6: 189-198, 1999.
34. Yan L and Spailholz JE. Generation of reactive oxygen species from the reaction of selenium compounds with thiols and mammary tumor cells. Biochem Pharmacol 45: 429-437, 1993.
35. Yasuda K, Watanabe H, Yamazaki D, and Toda S. Glutathione peroxidase activity of D,L-seleno-cystine and selenocystamine ions. Biochem Biophys Res Commun 96: 243-249, 1980.
36. Young MJ, Bresnitz EA, and Strom BL. Sample-size nomograms for interpreting negative clinical studies. Ann Intern Med 99: 248-251, 1983.
37. Zikic RV, Stajn AS, Ognjanovic BI, Saicie AS, Kostic MM, Pavlovic SZ, and Petrovic VM. The effect of cadmium and selenium on the antioxidant enzyme activities in rat heart. J Environ Pathol Toxicol Oncol 17: 259-264, 1998.