Identification of Crucial Histidines for Heme Binding in the N-terminal Domain of the Heme-regulated eIF2α Kinase

Journal of Biological Chemistry

Volumn 279, Issue 8, 2004, Pages 6778-6782

  Inuzuka, Takayuki ^a   Yun, Bo Geon ^c   Ishikawa, Haruto ^a,d   Takahashi, Satoshi ^a,b   Hori, Hiroshi ^b   Matts, Robert L ^c   Ishimori, Koichiro ^a   Morishima, Isao ^a  

^a KYOTO UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c OKLAHOMA STATE UNIVERSITY   (United States)

^d OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION SPECTROSCOPY; BIOSYNTHESIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; MUTAGENESIS; PROTEINS; RAMAN SPECTROSCOPY; ULTRAVIOLET SPECTROSCOPY;

MUTANTS;

BIOCHEMISTRY;

ALANINE; ALPHA GLOBIN; BETA GLOBIN; HISTIDINE; INITIATION FACTOR 2; PROTEIN KINASE R; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CIRCULAR DICHROISM; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME ANALYSIS; HEME SYNTHESIS; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DOMAIN; PROTEIN SYNTHESIS INHIBITION; RAMAN SPECTROMETRY; RETICULOCYTE; TISSUE SPECIFICITY; ULTRAVIOLET SPECTROSCOPY;

AMINO ACID SEQUENCE; ANIMALS; CIRCULAR DICHROISM; EIF-2 KINASE; ELECTRON SPIN RESONANCE SPECTROSCOPY; ESCHERICHIA COLI; HEME; HISTIDINE; HUMANS; LIGANDS; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; SPECTRUM ANALYSIS, RAMAN; ULTRAVIOLET RAYS;

EUKARYOTA;

EID: 1342282967     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C300464200     Document Type: Article

References (16)

1. Chen, J. J., and London, I. M. (1995) Trends Biochem. Sci. 20, 105-108
2. Chefalo, P. J., Oh, J., Rafie-Kolpin, M., Kan, B., and Chen, J. J. (1998) Eur. J. Biochem. 258, 820-830
3. Rafie-Kolpin, M., Chefalo, J. J., Hussain, Z., Hahn, J., Uma, S., Matts, R. L., and Chen, J. J. (2000) J. Biol. Chem. 275, 5171-5178
4. Uma, S., Matts, R. L., Guo, Y., White, S., and Chen, J. J. (2000) Eur. J. Biochem. 267, 498-506
5. Uma, S., Yun, B. G., Matts, R. L. (2001) J. Biol. Chem. 276, 14875-14883
6. Ishikawa, H., Yun, B. G., Takahashi, S., Hori, H., Matts, L., Ishimori, K., and Morishima, I. (2002) J. Am. Chem. Soc. 124, 13696-13697
7. Deinum, G., Stone, J. R., Babcock, G. T., and Marletta, M. A. (1996) Biochemistry 35, 1540-1547
8. Paul, K. G., Theorell, H., and Akeson, A. (1953) Acta Chem. Scand. 7, 1284-1287
9. Rivera, M., Barillas-Mury, C., Christensen, K. A., Little, J. W., Wells, M. A., and Walker, F. A. (1992) Biochemistry 31, 12233-12240
10. Li, X. Y., and Spiro, T. G. (1988) J. Am. Chem Soc. 110, 6024-6033
11. Hsu, M. C., and Woody, R. W. (1971) J. Am. Chem. Soc. 93, 3515-3525
12. Ihara, M., Takahashi, S., Ishimroi, K., and Morishima, I. (2000) Biochemistry 39, 5961-5970
13. Hirst, J., Wilcox, S. K., Ai, J., Moenne-Loccoz, P., Loehr, T. M., and Gooding, D. B. (2001) Biochemistry 40, 1274-1283
14. Adachi, S., Nagano, S., Ishimori, K., Watanabe, Y., Morishima, I., Egawa, T., Kitagawa, T., and Makino, R. (1993) Biochemistry 32, 241-252
15. Yoshioka, S., Takahashi, S., Hori, H., Ishimori, K., and Morishima, I. (2001) Eur. J. Biochem. 268, 252-259
16. Bois-Poltorasky, R., and Ehrenberg, A. (1967) Eur. J. Biochem. 2, 361-365