Importance of inlet air velocity in fluid bed drying of a granulation prepared in a high shear granulator

AAPS PharmSciTech

Volumn 1, Issue 4, 2000, Pages 3-

  Gao, Julia Z H ^a   Gray, David B ^a   Motheram, Rajeshwar ^a   Hussain, Munir A ^a  

^a DUPONT COMPANY   (United States)

Author keywords

Drying uniformity; Fluid bed drying; Inlet air velocity; Sample locations

Indexed keywords

DRUG;

AIRFLOW; ARTICLE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DRUG GRANULATION; DRUG INDUSTRY; DRUG MANUFACTURE; DRUG SOLUBILITY; DRUG STABILITY; FLUIDIZED BED; SHEAR STRENGTH; AIR; DESICCATION; DRUG FORMULATION; EQUIPMENT DESIGN; INSTRUMENTATION; MECHANICAL STRESS; METHODOLOGY; PHARMACEUTICS;

AIR MOVEMENTS; DESICCATION; DRUG COMPOUNDING; EQUIPMENT DESIGN; STRESS, MECHANICAL; TECHNOLOGY, PHARMACEUTICAL;

EID: 1342266617     PISSN: 15309932     EISSN: 15309932     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Van Scoik KG, Zoglio MA, Carstensen JT. Fluid bed drying. In: Lieberman HA, Lachman L, Schwartz JB, eds. From Pharmaceutical Dosage Forms: Tablets, Volume 2. New York: Marcel Dekker, Inc.;1990:91-96.
2. Zoglio MA, Streng WH, Carstensen JT. Diffusion model for fluidized-bed drying. Pharm Tech. 1975;64(11):1869-1873.
3. Parikh DM. Airflow in batch fluid-bed processing. Pharm Tech. 1991; 15 (3):100-110.
4. Rowe PN, Partridge BA, Cheney AG, Henwood GA, Lyall E. The mechanisms of solids mixing in fluidized beds. Trans Inst Chem Eng. 1965;32:T271-T286.
5. Davies L, Richardson JF. Gas interchange between bubbles and the continuous phase in a fluidized bed. Trans Inst Chem Eng. 1966;44:T293-T305.