Receptor recognition and specificity of interleukin-8 is determined by residues that cluster near a surface-accessible hydrophobic pocket

Journal of Biological Chemistry

Volumn 271, Issue 14, 1996, Pages 8228-8235

  Wernette Hammond, Mary Ellen ^a   Shyamala, Venkatakrishna ^a   Siani, Michael A ^a,b   Gallegos, Carol A ^a   Feucht, Paul H ^a   Abbott, Janine ^a   Lapointe, Gena Reza ^a   Moghadam, Mehrdad ^a   Khoja, Hamid ^a   Zakel, Joan ^a   Tekamp Olson, Patricia ^a  

^a NOVARTIS PHARMA AG   (Switzerland)

^b Gryphon Therapeutics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 8; INTERLEUKIN RECEPTOR;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; HUMAN; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN DETERMINATION; RECEPTOR AFFINITY; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANTIGENS, CD; BASE SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; CHEMOKINES; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; CHEMOTAXIS, LEUKOCYTE; DNA PRIMERS; GROWTH SUBSTANCES; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-8; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NEUTROPHILS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-8A; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SOLUBILITY;

EID: 13344281011     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.14.8228     Document Type: Article

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