A genetic test of the effects of mutations in PKA on mossy fiber ltp and its relation to spatial and contextual learning

Cell

Volumn 83, Issue 7, 1995, Pages 1211-1222

  Huang, Yan You ^a   Kandel, Eric R ^a   Varshavsky, Lauren ^a   Brandont, Eugene P ^c   Qi, Ming ^b   Idzerda, Rejean L ^b   Stanley McKnight, G ^b   Bourtchouladz, Roussoudan ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONDITIONING; CONTROLLED STUDY; ENTORHINAL CORTEX; FEAR; FEMALE; GENE MUTATION; GENE TARGETING; HIPPOCAMPUS; LEARNING; LONG TERM POTENTIATION; MALE; MAZE TEST; MOSSY FIBER; MOUSE MUTANT; NONHUMAN; OPEN FIELD BEHAVIOR; PRIORITY JOURNAL;

EID: 13344279399     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/0092-8674(95)90146-9     Document Type: Article

References (52)

1. PKCγ mutant mice exhibit mild deficits in spatial and contextual learning
2. The three-dimensional organization of the hippocampal formation: a review of anatomical data
3. Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the τ frequency
4. Memory deficits associated with sensescence: a neurophysiological and behavioral study in the rat
5. Spatial learning and memory processes: the search for their neurobiological mechanisms in the rat
6. Long-term potentiation of entorhinal afferents to the hippocampus: enhanced propagation of activity through the trisynaptic pathway
7. A synaptic model of memory: long-term potentiation in the hippocampus
8. Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
9. Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RIP subunit of cAMP-dependent protein kinase
10. Hippocampal mossy cell function: a speculative view
11. Distinct pattern of cAMPdependent protein kinase gene expression in mouse brain
12. Holoenzymes of CAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivityto cyclic nucleotides
13. Behavioral responses to novelty and structural variation of the hippocampus in mice. III. Quantitative genetic analysis of behavior in the open field
14. Spontaneous alternation behavior and the brain
15. Distraction and habituation in monkeys with limbic lesions
16. LTP and memory: can we enhance the connection?
17. Effect of CAMP stimulates a late stage of LTP in hippocampal CA1 neurons
18. Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
19. Hippocampal lesions and the orienting response
20. Histochemical demonstration of zinc in the hippocampal region of the domestic pig. III. The dentate area
21. Noradrenergic enhancement of long-term potentiation of mossy fiber synapses in the hippocampus
22. Recruitment of long-lasting and protein kinase A-dependent long-term potentiation in the CA1 region of hippocampus requires repeated tetanization
23. cAMP contributes to mossy fiber LTP by initiating both a covalently-mediately early phase and macromolecular synthesis-dependent late phase
24. Anatomical and behavioral analysis of hippocampal cell field in rats
25. On the role of the hippocampus in learning and memory in the rat
26. NMDAreceptor-independent long-term potentiation
27. Limbic lesions and the problems of stimulus-reinforcement associations
28. Spatial selectivity of unit activity in the hippocampal granular layer
29. Modality-specific retrograde amnesia of fear
30. The biochemistry of memory: a new and specific hypothesis
31. Long-term enhancement of hippocampal synaptic transmission and the acquisition of spatial information
32. Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge
33. Spatial localization does not depend on the presence of local cues
34. Synaptic plasticity and learning: selective impairment of learning in rats and blockade of long-term potentiation in vivo by the N-methyl-d-aspartate receptor antagonist AP5
35. Hippocampus, space and memory
36. Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning
37. Water-maze learning in the mouse correlates with variation in hippocampal morphology
38. Localization of A kinase through anchoring proteins
39. Impaired spatial learning in a-calcium-calmodulin kinase II mutant mice
40. Human regulatory subunit RIβ of cAMP-dependent protein kinases: expression, holoenzyme formation and microinjection into living cells
41. Hippocampal neuron responses in relation to normal and abnormal function
42. Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans
43. A behavioral analysis of spatial localization following electrolytic, kainate-orcolchicine-induced damage to the hippocampal formation in the rat
44. Hippocampal long-term potentiation: mechanisms and implications for memory
45. Computational constraints suggest the need for two distinct input systems to the hippocampal CA3 network
46. Computational analysis of the role of the hippocampus in memory
47. Mediation of hippocampal mossy fiber long-term potentiation by cyclic AMP
48. Organization of the entorhinal hippocampal system: a review of current anatomical data
49. Feedforward excitation of the hippocampus by afferents from the entorhinal cortex: redefinition of the role of the trisynaptic pathway
50. Monosynaptic excitation of hippocampal CA1 pyramidal cells by afferents from the entorhinal cortex
51. Comparison of two forms of long-term potentiation in single hippocampal neurons