Identification of T-cell determinants in natural immune responses to the Plasmodium falciparum apical membrane antigen (AMA-1) in an adult population exposed to malaria

Infection and Immunity

Volumn 64, Issue 3, 1996, Pages 1054-1059

  Lal, Altaf A ^a,d   Hughes, Molly A ^a,b   Oliveira, Denise A ^a   Nelson, Cecilia ^a   Bloland, Peter B ^a   Oloo, Aggrey J ^c   Hawley, William E ^a,c   Hightower, Allen W ^a   Nahlen, Bernard L ^a,c   Udhayakumar, Venkatachalam ^a  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MALARIA VACCINE; PROTOZOAL PROTEIN; PROTOZOAL VACCINE; SYNTHETIC PEPTIDE; T LYMPHOCYTE ANTIGEN;

ADOLESCENT; ADULT; AGED; APICAL MEMBRANE; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG FORMULATION; FEMALE; HUMAN; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALARIA; MALE; MONONUCLEAR CELL; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; T LYMPHOCYTE; VACCINE PRODUCTION;

EID: 13344277356     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.3.1054-1059.1996     Document Type: Article

References (36)

1. Anders, R. F. Personal communication.
2. 1a Anders, R., and A. J. Saul. 1994. Candidate antigens for an asexual blood stage vaccine against falciparum malaria, p. 169 In M F. Good and A. J Saul (ed.), Molecular immunological considerations in malaria vaccine development - 1994 CRC Press, Boca Raton. Fla.
3. Barany, G., and R. P. Merrfield. 1980. Solidphase peptide synthesis, p 1-284 In E. Gross and J Meienhofer (ed ), The peptides Academic Press, New York.
4. Beier, J. C., P. V. Perkins, F. K. Onyango, T. P. Gargan, C. N. Oster, R. E. Whitmire, D. K. Koech, and C. R. Roberts. 1990. Characterization of malaria transmission by Anopheles (Diptera: Culicidae) in western Kenya in preparation for malaria vaccine trials. J Med. Entomol. 27:570-577
5. Cheng, Q., and A. J. Saul. 1994. Sequence analysis of the apical membrane antigen I (AMA-1) of Plasmodium vivax Mol Biochem. Parasitol. 65:183-187.
6. Collins, W. E., D. Pye, P. E. Crewter, K. L. Vandeberg, G. G. Galland, A. J. Sulzer, D. J. Kemp, S. J. Edwards, R. L. Coppel, J. S. Sullivan, C. L. Morris, and R. F. Anders. 1994. Protective immunity induced in squirrel monkeys with recombinant apical membrane antigen-1 of Plasmodium fragile Am. J Trop. Med. Hyg. 51:711-719.
7. Crewther, P. E., J. G. Culvenor, A. Silva, J. A. Cooper, and R. F. Anders. 1990. Plasmodium falciparum: two antigens of similar size are located in different compartments of the rhoptry. Exp. Parasitol. 70:193-206.
8. Deans, J. A., T. Alderson, A. W. Thomas, G. H. Mitchell, E. S. Lennox, and S. Cohen. 1982. Rat monoclonal antibodies which inhibit the in vitro multiplication of Plasmodium knowlesi. Clin Exp. Immunol. 49:297-309.
9. Deans, J. A., A. M. Knight, W. C. Jean, A. P. Waters, S. Cohen, and G. H. Mitchell. 1988. Vaccination trial in rhesus monkey with minor, invariant, Plasmodium knowlesi Parasite Immunol 10:535-552.
10. de la Cruz, V. F., A. A. Lal, and T. F. McCutchan. 1987. Sequence variation in putative functional domains of the circumsporozoite protein of Plasmodium falciparum. J. Biol. Chem. 262:11935-11937.
11. de la Cruz, V. F., W. L. Maloy, L. H. Miller, A. A. Lal, M. F. Good, and T. F. McCutchan. 1988. Lack of cross-reactivity between variant T cell determinants from malaria circumsporozoite protein. J. Immunol. 141:2456-2460
12. Doolan, D. L., H. P. Beck, and M. F. Good. 1993. Evidence for restricted activation of distinct CD4 T cell subsets in response to the Plasmodium falciparum circumsporozoite protein in Papua New Guinea. Parasite Immunol. 16:129-136.
13. Engelhard, H. 1994 Structure of peptides associated with class I and class II molecules. Annu. Rev. Immunol. 12:181-207.
14. Greenwood, B. M., K. Marsh, and R. W. Snow. 1992. Why do some African children develop severe malaria? Parasitol Today 7:277-281.
15. 13a. Hawley, W. E., A. V. O. Ofulla, A. W. Hightower, A. J. Oloo, A. A. Lal, and B. L. Nahlen. Unpublished data.
16. Ho, M., H. K. Webster, S. Looareesuwan, W. Supanaranond, R. Phillips, P. Chanthavanich, and D. Warrell. 1986. Antigen-specific immunosuppression in human malaria due to P. falciparum. J. Infect. Dis. 153:763-771.
17. Kremsner, P., G. Zotter, H. Feldmeier, W. Graninger, R. Roraima, R. Jansen-Rosseck, and U. Bienzle. 1990 Immune response in patients during and after P falciparum infection J Infect Dis. 161:1025-1028
18. Lockyer, M. J., K. Marsh, and C. I. Newbold. 1989. Wild isolates of Plasmodium falciparum show extensive polymorphism in T cell epitopes of the circumsporozoite protein. Mol. Biochem. Parasitol. 37:275-280.
19. Margalit, H., J. L. Spouge, J. L. Cornette, K. B. Cease, C. Delisi, and J. A. Berzofsky. 1987. Prediction of immunodominant helper T-cell antigenic sites from the primary sequence. J Immunol. 138:2213-2219.
20. Marshall, V. M., G. M. Peterson, A. M. Lew, and D. J. Kemp. 1989. Structure of the apical membrane antigen I (AMA-1) of Plasmodium chabaudi. Mol. Biochem Parasitol. 37:281 284
21. Moreno, A., P. Clavijo, R. Edelman, J. Davis, M. Sztein, F. Sinigaglia, and E. Nardin. 1993. CD4+ T cell clones obtained from Plasmodium falciparum sporozoite-immunized volunteers recognize polymorphic sequences of the circumsporozoite piotein. J. Immunol 151:489-499
22. Mosier, D. E., and B. Subbarao. 1982. Thymus-indcpendent antigens: complexity of B-lymphocyte activation revealed. Immunol. Today 3:217-222.
23. Oaks, S. C., Jr., V. S. Mitchell, G. W. Pearson, and C. J. Carpenter (ed.). 1991. Malaria, obstacles and opportunities. National Academy Press. Washington, D.C
24. 21a. Oliveira, D., V. Udhayakumar, P. B. Bloland, Y. P. Shi, B. L. Nahlen, A. J. Oloo, W. E. Hawley, and A. A. Lal. Conservation of the Plasmodium falciparum apical membrane antigen-1 (AMA-1) Mol. Biochem. Parasitol., in press.
25. Peterson, M. G., M. V. Marshall, J. A. Smythe, P. E. Crewther, A. Lew, A. Silva, R. F. Anders, and D. J. Kemp. 1989. Integral membrane protein located in the apical complex of Plasmaduim fulciparum. Mol Cell. Biol. 9:3151-3154.
26. Peterson, M. G., P. Ngujen-Dinh, V. M. Marshall, J. F. Elliott, W. E. Collins, R. F. Anders, and D. J. Kemp. 1990. Apical membrane antigen of Plasmodium fragile. Mol. Biochem. Parasitol. 39:279-284.
27. Quakyi, I. A., J. Currier, A. Fell, D. W. Taylor, T. Roberte, R. A. Houghten, R. D. England, J. A. Berzofsky, L. H. Miller, and M. F. Good. 1994. Analysis of human T cell clones specific for conserved peptide sequences within malaria proteins. J. Immunol. 153:2082-2092.
28. Schofield, L., and P. Uadia. 1990 Lack of Ir gene control in the immune response to malaria. I. A thymus independent antibody response to the repetitive surface protein of sporozoites J. Immunol. 144:2781-2788.
29. Shi, Y. P., M. P. Alpers, M. M. Povoa, and A. A. Lal. 1992. Diversity in the immunodominant determinants of the circumsporozoite protein of Plasmodium falciparum parasites from malaria-endemic regions of Papua New Guinea and Brazil Am. J. Trop. Med. Hyg 47:844-851.
30. Sinigaglia, F., B. Takacs, H. Jacot, H. Matile, J. R. L. Pink, A. Crisanti, and H. Bujard. 1988. Nonpolymorphic region of p190, a protein of the Plasmodium falciparum erythrocytic stage, contains both B and T cell epitopes. J. Immunol. 140:3568-3572.
31. Thomas, A. W., J. A. Deans, G. H. Mitchell, T. Alderson, and S. Cohen. 1984. The Fab fragments of monoclonal IgG to a merpozoite surface antigen inhibit Plasmodium knowlest invasion of erythrocytes Mol Biochem. Parasitol. 13:187-199.
32. Thomas, A. W., A. P. Waters, and D. Carr. 1990. Analysis of variation in PF 83, an erythrocytic merozoite vaccine candidate antigen of Plasmodium falciparum Mol Biochem. Farasitol 42:285-288.
33. Udhayakumar, V., D. Anyona, S. Kariuki, Y. Shi, P. B. Bloland, O. H. Branch, W. Weiss, B. L. Nahlen, D. C. Kaslow, and A. A. Lal. 1995 Identification of T and B cell epitopes recognized by humans in the C-terminal 42-kDa domain of the Plasmodium falciparum merozoite surface protein (MSP)-1. J. Immunol 154:6022-6030
34. Udhayakumar, V., Y. Shi, S. Kumar, D. L. Jue, R. M. Wohlhueter, and A. A. Lal. 1994. Antigenic diversity in the circumsporozoite protein of Plasmodium falciparum abrogates cytotoxic T-cell recognition. Infect. Immun. 62:1410-1413.
35. Waters, A. P., A. W. Thomas, J. A. Deans, G. H. Mitchell, D. E. Hudson, L. H. Miller, T. F. McCutchan, and S. Cohen. 1990 A merozoite receptor protein from Plasmodium knowlest is highly conserved and distributed throughout Plasmodium. J. Biol. Chem. 265:17974-17979.
36. Zevering, Y., F. Amante, A. Smillte, J. Currier, G. Smith, R. A. Houghten, and M. F. Good. 1992 High frequency of malaria-specific T cells in nonexposed humans. Eur. J. Immunol. 22:689-696.