Handwashing in the intensive care unit: A big measure with modest effects

Journal of Hospital Infection

Volumn 59, Issue 3, 2005, Pages 172-179

  Silvestri, Luciano ^a   Petros, A J ^b   Sarginson, R E ^c   de la Cal, M A ^d   Murray, A E ^e   van Saene, H K F ^f  

^a Unit of Anesthesia and Intensive Care   (Italy)

^b GREAT ORMOND STREET HOSPITAL   (United Kingdom)

^c ALDER HEY CHILDREN S HOSPITAL   (United Kingdom)

^d HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^e WIRRAL UNIVERSITY TEACHING HOSPITAL   (United Kingdom)

^f UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Handwashing; Infection; Intensive care unit

Indexed keywords

CHLORHEXIDINE; CHLOROXYLENOL; POVIDONE IODINE; SOAP; TRICLOSAN;

BACTERIAL TRANSMISSION; BACTERIUM CULTURE; CLINICAL TRIAL; EVIDENCE BASED MEDICINE; HAND WASHING; HEALTH CARE PERSONNEL; HEALTH SURVEY; HOSPITAL HYGIENE; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION RATE; INTENSIVE CARE UNIT; MEDICAL LITERATURE; NONHUMAN; RANDOMIZATION; RECTUM; REVIEW; THROAT CULTURE;

CLINICAL TRIALS; CROSS INFECTION; DISEASE TRANSMISSION, PROFESSIONAL-TO-PATIENT; GUIDELINE ADHERENCE; HANDWASHING; HUMANS; INFECTION CONTROL; INTENSIVE CARE UNITS;

EID: 13344277189     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2004.11.005     Document Type: Review

References (44)

1. J.M. Conly S. Hill J. Ross J. Lertzman T.J. Louie Handwashing practices in an intensive care unit: The effects of an educational program and its relationship to infection rates Am J Infect Control 17 1989 330-339
2. S.E. Beekman D.K. Henderson Controversies in isolation policies and practices. In: R.P. Wenzel (Ed.). Prevention and control of nosocomial infections 3rd edn 1997 Williams and Wilkins Baltimore 71-84
3. S.K. Pingleton J.-Y. Fagon K.V. Leeper Patient selection for clinical investigation of ventilator-associated pneumonia Chest 102 Suppl 1992 553S-556S
4. J.M. Boyce D. Pittet Guideline for hand hygiene in health-care settings: recommendation of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force Infect Control Hosp Epidemiol 23 Suppl 2002 S3-S40
5. Liberati A, D'Amico R, Pifferi S, Torri V, Brazzi L. Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care (Cochrane review). The Cochrane Library, Issue 1. Chichester: Wiley; 2004
6. Handwashing Liaison Group Hand washing. A modest measure-with big effects BMJ 318 1999 686
7. L. Silvestri M. Milanese L. Oblach et al. Enteral vancomycin to control methicillin-resistant Staphylococcus aureus outbreak in mechanically ventilated patients Am J Infect Control 30 2002 391-399
8. M.A. de la Cal E. Cerdà H.K.F. van Saene et al. Effectiveness and safety of enteral vancomycin to control endemicity of methicillin-resistant Staphylococcus aureus in a medical/surgical intensive care unit J Hosp Infect 56 2004 175-183
9. L. Silvestri H.K.F. van Saene M. Milanese et al. Prevention of MRSA pneumonia by oral vancomycin decontamination: A randomised trial Eur Respir J 23 2004 921-926
10. N. Khairulddin L. Bishop T.L. Lamagni M. Sharland G. Duckworth Emergence of methicillin-resistant Staphylococcus aureus (MRSA) bacteraemia among children in England and Wales, 1990-2001 Arch Dis Child 89 2004 378-379
11. Chief Medical Officer Winning ways. Working together to reduce healthcare associated infection in England Report from the Chief Medical Officer 2003 Department of Health Publications London
12. E. Larson Skin hygiene and infection prevention: More of the same or different approaches? Clin Infect Dis 29 1999 1287-1294
13. M. Casewell I. Phillips Hands as route of transmission for Klebsiella species BMJ 2 1977 1315-1317
14. R.M. Massanari W.J. Hierholzer A crossover comparison of antiseptic soaps on nosocomial infection rates in the intensive care unit Am J Infect Control 12 1984 247-248
15. D.G. Maki The use of antiseptics for handwashing by medical personnel J Chemother 1 Suppl. 1 1989 3-11
16. B. Simmons J. Bryant K. Neiman L. Spencer K. Arheart The role of handwashing in prevention of endemic intensive care unit infections Infect Control Hosp Epidemiol 11 1990 589-594
17. B.N. Doebbeling G.L. Stanley C.T. Sheetz et al. Comparative efficacy of alternative hand-washing agents in reducing nosocomial infections in intensive care units N Engl J Med 327 1992 88-93
18. J. Webster J.L. Faoagali D. Cartwright Elimination of methicillin-resistant Staphylococcus aureus from a neonatal intensive care unit after hand washing with triclosan J Paediatr Child Health 30 1994 59-64
19. M. Slota M. Green A. Farley J. Janosky J. Carcillo The role of gown and glove isolation and strict handwashing in the reduction of nosocomial infection in children with solid organ transplantation Crit Care Med 29 2001 405-412
20. W.G. Koss T.M. Khalili J.F. Lemus M.M. Chelly D.R. Margulies M.M. Shabot Nosocomial pneumonia is not prevented by protective contact isolation in the surgical intensive care unit Am Surg 67 2001 1140-1144
21. P.J. Sharek W.E. Benitz N.J. Abel M.J. Freeburn M.L. Mayer D.A. Bergman Effect of an evidence-based hand washing policy on hand washing rates and false-positive coagulase negative Staphylococcus blood and cerebrospinal fluid culture rates in a level III NICU J Perinatol 22 2002 137-143
22. W.R. Jarvis Handwashing - the Semmelweis lesson forgotten? Lancet 344 1994 1311-1312
23. I.P. Semmelweis Die Aetiologie, der Begriff und die Prophylaxis des Kindbettfiebers 1861 CA Hartleben Pest
24. R.P. Dellinger J.M. Carlet H. Masur et al. Surviving sepsis campaign guidelines for management of severe sepsis and septic shock Crit Care Med 32 2004 858-873
25. H.K.F. van Saene V. Damjanovic A.E. Murray M.A. de la Cal How to classify infections in intensive care units - the carrier state, a criterion whose time has come? J Hosp Infect 33 1996 1-12
26. A.E. Murray J.J. Chambers H.K.F. van Saene Infections in patients requiring ventilation in intensive care: Application of a new classification Clin Microbiol Infect 4 1998 94-99
27. L. Silvestri C. Monti-Bragadin M. Milanese et al. Are ICU infections really nosocomial? A prospective observational cohort study in mechanically ventilated patients J Hosp Infect 42 1999 125-133
28. M.A. de la Cal E. Cerdà P. Garcia-Hierro et al. Pneumonia in severe burns: A classification according to the concept of the carrier state Chest 119 2001 1160-1165
29. A.J. Petros M. O'Connell C. Roberts P. Wade H.K.F. van Saene Systemic antibiotics fail to clear multiresistant Klebsiella from a pediatric intensive care unit Chest 119 2001 862-866
30. L. Silvestri R.E. Sarginson J. Hughes M. Milanese D. Gregori H.K.F. van Saene Most nosocomial pneumonias are not due to nosocomial bacteria in ventilated patients. Prospective evaluation of the accuracy of the 48 h time cut-off using carriage as the gold standard Anaesth Intensive Care 30 2002 275-282
31. R.E. Sarginson N. Taylor N. Reilly P.B. Baines H.K.F. van Saene Infection in prolonged pediatric critical illness: A prospective four year study based on knowledge of the carrier state Crit Care Med 32 2004 839-847
32. E. Girou S. Loyeau P. Legrand F. Oppein C. Brun-Buisson Efficacy of handrubbing with alcohol based solution versus standard handwashing with antiseptic soap: Randomised clinical trial BMJ 325 2002 362-365
33. E.L. Larson A.E. Aiello J. Bastyr et al. Assessment of two hand regimens for intensive care unit personnel Crit Care Med 29 2001 944-951
34. B. Nystrom Optimal design/personnel for control of intensive care unit infections Infect Control 4 1983 388-390
35. T.C. Salzman J.J. Clark L. Klemm Hand contamination of personnel as a mechanism of cross-infection in nosocomial infections with antibiotic-resistant Escherichia coli and Klebsiella/Aerobacter Antimicrob Agents Chemother 7 1967 97-100
36. K. Crossley B. Landesmann D. Zaske An outbreak of infections caused by strains of Staphylococcus aureus resistant to methicillin and aminoglycosides. Epidemiologic studies J Infect Dis 139 1979 280-287
37. M.I.J. Khan Interruption of shigellosis by handwashing Trans R Soc Trop Med 76 1982 164-168
38. P.H.I. Tarr Escherichia coli 0157:H7. Clinical, diagnostic, and epidemiological aspects of human infection Clin Infect Dis 20 1986 1-10
39. C. Brun-Buisson P. Legrand A. Rauss et al. Intestinal decontamination for control of nosocomial multiresistant gram-negative bacilli. Study of an outbreak in an intensive care unit Ann Intern Med 110 1989 873-881
40. M.E. Taylor B.A. Oppenheim Selective decontamination of gastrointestinal tract as an infection control measure J Hosp Infect 17 1991 271-278
41. V. Damjanovic C.M. Connolly H.K.F. van Saene et al. Selective decontamination with nystatin for control of a Candida outbreak in a neonatal intensive care unit J Hosp Infect 24 1993 245-259
42. D. Pittet P. Mourouga T.V. Perneger the Members of Infection Control Program Compliance with handwashing in a teaching hospital Ann Intern Med 130 1999 126-130
43. M.L. Rotter Handwashing, hand disinfection and skin disinfection. In: G. Mayhall editor. Hospital epidemiology and infection control 2nd edn 1999 Williams and Wilkins Baltimore 691-709
44. E. de Jonge M.J. Schultz L. Spanjaard P.M.M. Bossuyt M.B. Vroom J. Dankert Effects of selective decontamination of the digestive tract on mortality and acquisition of resistant bacteria in intensive care: A randomised trial Lancet 362 2003 1011-1016