Use of the weighted jackknife method to calculate the variance in cellular-specific protein secretion rate: Application to monoclonal antibody secretion rate kinetics in response to osmotic stress

Biotechnology and Bioengineering

Volumn 50, Issue 2, 1996, Pages 184-196

  Yang, Xianhui ^a   Oehlert, Gary W ^a   Flickinger, Michael C ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

animal cell culture; hybridoma; osmotic stress; specific secretion rate; variance of specific secretion rate

Indexed keywords

ANIMAL CELL CULTURE; ANTIBODIES; BATCH CELL CULTURE; CELLS; DIFFERENTIAL EQUATIONS; MATHEMATICAL MODELS; NUMERICAL METHODS; REACTION KINETICS;

CELLULAR SPECIFIC PROTEIN SECRETION; HYBRIDOMA TECHNOLOGY; HYPEROSMOTIC MEDIA; MAMMALIAN CELL; MONOCLONAL ANTIBODY SECRETION RATE; OSMOTIC STRESS; STANDARD DEVIATION; WEIGHTED JACKKNIFE METHOD;

PROTEINS;

MONOCLONAL ANTIBODY;

ANIMAL CELL; ARTICLE; HYBRIDOMA; MOUSE; NONHUMAN; OSMOTIC STRESS; PROTEIN SECRETION; STATISTICAL ANALYSIS;

EID: 13344270396     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19960420)50:2<184::AID-BIT7>3.0.CO;2-I     Document Type: Article

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