Salivary EGF regulates eosinophil-derived TGF-α expression in hamster oral wounds

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 270, Issue 1 33-1, 1996, Pages

  Yang, James ^b   Tyler, Lisa W ^b   Donoff, R Bruce ^b   Song, Baizheng ^b   Torio, Angel J ^b   Gallagher, George T ^b   Tsuji, Takanori ^b   Elovic, Aram ^b   McBride, Jim ^b   Yung, Chou Ming ^b   Galli, Stephen J ^b   Weller, Peter F ^b   Wong, David T W ^a  

^a HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

^b NONE

Author keywords

cytokines; oral wound healing; saliva; salivary gland

Indexed keywords

EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EOSINOPHILIA; GENE EXPRESSION REGULATION; HAMSTER; IMMUNOMODULATION; IMMUNOREGULATION; MALE; MOUTH LESION; NONHUMAN; PRIORITY JOURNAL; SALIVA ANALYSIS; SALIVATION; WOUND HEALING;

EID: 13344262698     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.1996.270.1.g191     Document Type: Article

References (30)

1. Abraham, W. M., M. W. Sielczak, A. Ahmed, A. Cortes, I. T. Lauredo, J. Kim, B. Pepinsky, C. D. Benjamin, D. R. Leone, R. R. Lobb, and P. F. Weller. Alpha 4-integrins mediate antigen-induced late bronchial responses and prolonged airway hyperresponsiveness in sheep. J. Clin. Invest. 93: 776-787, 1994.
2. Anklesaria, P., J. Teixido, M. Laiho, J. H. Pierce, J. S. Greenberger, and J. Massague. Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor-α to epidermal growth factor receptors promotes cell proliferation. Proc. Natl. Acad. Sci. USA 87: 3289-3293, 1990.
3. Barrandon, Y., and H. Green. Cell migration is essential for sustained growth of keratinocytes colonies: the role of transforming growth factor-α and epidermal growth factor. Cell 50: 1131-1137, 1987.
4. Bassett, E. G., J. R. Baker, and P. de Souza. A light microscopical study of healing incised dermal wounds in rats, with special reference to eosinophil leucocytes and to the collagenous fibres of the periwound areas. Br. J. Exp. Pathol., 58: 581-605, 1977.
5. Bertolami, C. N., and R. B. Donoff. Identification, characterization, and partial purification of mammalian skin wound hyaluronidase. J. Invest. Dermatol. 79: 417-421, 1982.
6. Bochner, B. S., F. W. Luscinskas, M. J. Gimbrone, W. Newman, S. A. Sterbinsky, A. C. Derse, D. Klunk, and R. P. Schleimer. Adhesion of human basophils, eosinophus, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules. J. Exp. Med. 173: 1553-1557, 1991.
7. Coffey, R. J., J. R. Derynck, J. N. Wilcox, T. S. Bringman, A. S. Goustin, H. L. Moses, and M. R. Pittelkow. Production and auto-induction of transforming growth factor-α in human keratinocytes. Nature Lond. 328: 817-820, 1987.
8. Derynck, R., A. B. Roberts, M. E. Winkler, E. Y. Chen, and D. V. Goeddel. Human transforming growth factor-alpha: precursor structure and expression in E. coli. Cell 38: 287-297, 1984.
9. Dobrina, A., R. Menegazzi, T. M. Carlos, E. Nardon, R. Cramer, T. Zacchi, J. M. Harlan, and P. Patriarca. Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor. J. Clin. Invest. 88: 20-26, 1991.
10. Elices, M. J., L. Osborn, Y. Takada, C. Crouse, S. Luhowskyj, M. E. Hemler, and R. R. Lobb. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell 60: 577-584, 1990.
11. Humphreys-Beher, M. G., S. P. Macauley, N. Chegini, G. van Setten, K. Purushotham, C. Stewart, T. T. Wheeler, and G. S. Schultz. Characterization of the synthesis and secretion of transforming growth factor-alpha from salivary glands and saliva. Endocrinology 134: 963-970, 1994.
12. Ignotz, R. A., B. Kelly, R. J. Davis, and J. Massague. Biologically active precursor for transforming growth factor type-α, released by retrovirally transformed cells. Proc. Natl. Acad. Sci. USA 83: 6307-6311, 1986.
13. Lee, D. C., T. M. Rose, N. R. Webb, and G. J. Todaro. Cloning and sequence analysis of a cDNA for rat transforming growth factor-alpha. Nature Lond. 313, 489-491, 1985.
14. Luetteke, N. C., T. H. Qiu, R. L. Peiffer, P. Oliver, O. Smithies, and D. C. Lee. TGF-α deficiency results in hair follicle and eye abnormalities in targeted and Wave-1 mice. Cell 73: 263-278, 1993.
15. Mann, G. B., K. J. Fowler, A. Gabriel, E. C. Nice, R. L. Williams, and A. R. Dunn. Mice with a null mutation of the TGF-α gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 73: 246-261, 1993.
16. Molhuizen, H. O., H. A. Alkemade, P. L. Zeeuwen, G. J. de Jongh, B. Wieringa, and J. Schalkwijk. SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase crosslinking. J. Biol. Chem. 268: 12028-12032, 1993.
17. Mueller, S. G., A. J. Paterson, and J. E. Kudlow. Transforming growth factor-α in arterioles: cell surface processing of its precursor by elastases. Mol. Cell Biol. 10: 4596-4602, 1990.
18. Pandiella, A., M. W. Bosenberg, E. J. Huang, P. Besmer, and J. Massague. Cleavage of membrane-anchored growth factors involves distinct protease activities regulated through common mechanisms. J. Biol. Chem. 267: 24028-24033, 1992.
19. Pandiella, A., and J. Massague. Cleavage of the membrane precursor for transforming growth factor-α is a regulated process. Proc. Natl. Acad. Sci. USA 88: 1726-1730, 1991.
20. Pretolani, M., C. Ruffié, J.-R. Lapa e Silva, D. Joseph, R. R. Lobb, and B. B. Vargaftig. Antibody to very late activation antigen 4 prevents antigen-induced bronchial hyperreactivity and cellular infiltration in the guinea pig. J. Exp. Med. 180: 795-805, 1994.
21. Schalkwijk, J., C. de Roo, and G. J. de Jongh. Skin-derived antileukoproteinase (SKALP), an elastase inhibitor from human keratinocytes. Purification and biochemical properties. Biochim. Biophys. Acta 1096: 148-154, 1991.
22. Sciubba, J. J., J. P. Waterhouse, and J. Meyer. A fine structural comparison of the healing of incisional wounds of mucosa and skin. J. Oral Pathol. 7: 214-219, 1978.
23. Todd, R., R. B. Donoff, T. Chiang, M. Y. Chou, A. Elovic, G. Gallagher, and D. T. W. Wong. The eosinophil as a cellular source of TGF-α in healing cutaneous wound. Am. J. Pathol. 138: 1307-1313, 1991.
24. Weg, V. B., T. J. Williams, R. R. Lobb, and S. Nourshargh. A monoclonal antibody recognizing very late activation antigen-4 inhibits eosinophil accumulation in vivo. J. Exp. Med. 177: 561-566, 1993.
25. Weller, P. F. Roles of eosinophils in allergy. Curr. Opin. Immunol. 4: 782-787, 1992.
26. Weller, P. F., T. H. Rand, S. E. Goelz, R. G. Chi, and R. R. Lobb. Human eosinophil adherence to vascular endothelium mediated by binding to vascular cell adhesion molecule 1 and endothelial leukocyte adhesion molecule 1. Proc. Natl. Acad. Sci. USA 88: 7430-7433, 1991.
27. Wong, D. T. W., R. B. Donoff, J. Yang, B.-Z. Song, K. Matossian, N. Nagura, A. Elovic, J. McBride, G. Gallagher, R. Todd, T. Chiang, L. S.-S. Chou, M. Y. Chou, S. J. Galli, and P. F. Weller. Sequential expression of TGF-α and TGF-β1 by eosinophils during cutaneous wound healing in the hamster. Am. J. Pathol. 143: 130-142, 1993.
28. Wong, D. T. W., G. T. Gallagher, R. Gertz, A. L. C. Chang, and G. Shklar. Transforming growth factor-α in chemically transformed hamster oral keratinocytes. Cancer Res. 48: 3130-3134, 1988.
29. Wong, D. T. W., P. F. Weller, S. J. Galli, A. Elovic, T. H. Rand, G. T. Gallagher, T. Chiang, M. Y. Chou, K. Matossian, J. McBride, M. Tsai, and R. Todd. Human eosinophils express transforming growth factor alpha. J. Exp. Med. 172: 673-681, 1990.
30. Yeh, Y.-C., H.-Y. Guh, J. Yeh, and H.-W. Yeh. Transforming growth factor type alpha in normal human adult saliva. Mol. Cell. Endocrinol. 67: 247-255, 1989.