One-pot, four-component reaction of isocyanides, dimethyl acetylenedicarboxylate, and cyclobutene-1,2-diones: A synthesis of novel spiroheterocycles

Tetrahedron Letters

Volumn 46, Issue 8, 2005, Pages 1337-1339

  Nair, Vijay ^a   Menon, Rajeev S ^a   Deepthi, Ani ^a   Rema Devi, B ^a   Biju, A T ^a  

^a REGIONAL RESEARCH LABORATORY CSIR   (India)

Author keywords

Dimethyl acetylenedicarboxylate; Isocyanides; Multicomponent reactions; Zwitterions

Indexed keywords

ACETYLENEDICARBOXYLIC ACID DIMETHYL ESTER; ALKENE DERIVATIVE; ISOCYANIC ACID DERIVATIVE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; NUCLEAR MAGNETIC RESONANCE; SYNTHESIS;

INSERTION SEQUENCES;

EID: 13244295523     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.12.117     Document Type: Article

References (17)

1. A. Dömilng, and I. Ugi Angew. Chem., Int. Ed. 39 2000 3168 3210
2. I. Ugi, B. Werner, and A. Dömilng Molecules 8 2003 53 66
3. J. Zhu Eur. J. Org. Chem. 2003 1133 1144 and references cited therein
4. V. Nair, C. Rajesh, A.U. Vinod, S. Bindu, A.R. Sreekanth, J.S. Mathen, and L. Balagopal Acc. Chem. Res. 36 2003 899 907
5. V. Nair, A.U. Vinod, N. Abhilash, R.S. Menon, V. Santhi, L.R. Varma, S. Viji, S. Mathew, and R. Srinivas Tetrahedron 59 2003 10279 10286
6. V. Nair, A.U. Vinod, R. Ramesh, R.S. Menon, R.L. Varma, S. Mathew, and A. Chiaroni Heterocycles 58 2002 147 151
7. R. West Oxocarbons 1980 Academic New York
8. A.H. Schmidt, and W. Ried Synthesis 1978 1 22
9. H. Knorr, and W. Ried Synthesis 1978 649 666
10. A.H. Schmidt, and W. Ried Synthesis 1978 869 880
11. J.O. Karisson, N.V. Nguyen, L.D. Foland, and H.W. Moore J. Am. Chem. Soc. 107 1985 3392 3393
12. H.A. Staab, and J. Ipaktschi Chem. Ber. 101 1968 1457
13. L.S. Liebeskind Tetrahedron 45 1989 3053 3060
14. L.S. Liebeskind, S. Iyer, and C.F. Jewell Jr. J. Org. Chem. 51 1986 3065 3067
15. V. Nair, and S. Kumar Synlett 1996 1143 1147
16. R.C. De Selms, C.J. Fox, and R.C. Riordan Tetrahedron Lett. 11 1970 781 782
17. 6: C, 72.22; H, 7.07; N, 4.68%. Found: C, 72.41; H, 6.92; N, 5.07%