A survey of clusterin and fascin expression in sarcomas and spindle cell neoplasms: Strong clusterin immunostaining is highly specific for follicular dendritic cell tumor

Modern Pathology

Volumn 18, Issue 2, 2005, Pages 260-266

  Grogg, Karen L ^a,b   Macon, William R ^a   Kurtin, Paul J ^a   Nascimento, Antonio G ^a  

^a MAYO CLINIC   (United States)

^b Dept of Lab Medicine and Pathology ^*  (United States)

Author keywords

Clusterin; Fascin; Follicular dendritic cell tumor; Immunohistochemistry; Sarcoma

Indexed keywords

CLUSTERIN; FASCIN;

ANGIOSARCOMA; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; DERMATOFIBROMA; FOLLICULAR DENDRITIC CELL; HEMANGIOMATOSIS; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LEIOMYOSARCOMA; MALIGNANT FIBROUS HISTIOCYTOMA; PLASMA CELL GRANULOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARCOMA; SPINDLE CELL; SPINDLE CELL CARCINOMA; THYMOMA;

CARRIER PROTEINS; CLUSTERIN; DENDRITIC CELLS, FOLLICULAR; GASTROINTESTINAL STROMAL TUMORS; GLYCOPROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MELANOMA; MICROFILAMENT PROTEINS; MOLECULAR CHAPERONES; SARCOMA; SKIN NEOPLASMS; SOFT TISSUE NEOPLASMS;

EID: 13244292224     PISSN: 08933952     EISSN: None     Source Type: Journal    
DOI: 10.1038/modpathol.3800294     Document Type: Article

References (22)

1. Biddle DA, Ro JY, Yoon GS, et al. Extranodal follicular dendritic cell sarcoma of the head and neck region: three new cases, with a review of the literature. Mod Pathol 2002;15:50-58.
2. Weiss LM, Grogan TM, Muller-Hermelink H-K, et al. WHO classification of histiocytic and dendritic cell neoplasms. In: Jaffe ES, Harris NL, Stein H, Vardiman JW (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press: Lyon, France, 2001, pp 274-289.
3. Perez-Ordonez B, Rosai J. Follicular dendritic cell tumor: review of the entity. Semin Diagn Pathol 1998;15:144-154.
4. Grogg KL, Lae ME, Kurtin PJ, et al. Clusterin expression distinguishes follicular dendritic cell tumors from other dendritic cell neoplasms: report of a novel follicular dendritic cell marker and clinicopathologic data on 12 additional follicular dendritic cell tumors and 6 additional interdigitating dendritic cell tumors. Am J Surg Pathol 2004;28:988-998.
5. Pinkus GS, Lones MA, Matsumura F, et al. Langerhans cell histiocytosis immunohistochemical expression of fascin, a dendritic cell marker. Am J Clin Pathol 2002;118:335-343.
6. Pinkus GS, Pinkus JL, Langhoff E, et al. Fascin, a sensitive new marker for Reed-Sternberg cells of Hodgkin's disease: evidence for a dendritic or B cell derivation? Am J Pathol 1997;150:543-562.
7. Pantanowitz L, Antonioli DA, Pinkus GS, et al. Inflammatory fibroid polyps of the gastrointestinal tract: evidence for a dendritic cell origin. Am J Surg Pathol 2004;28:107-114.
8. Wellman A, Thieblemont C, Pittaluga S, et al. Detection of differentially expressed genes in lymphomas using cDNA arrays: identification of clusterin as a new diagnostic marker for anaplastic large cell lymphomas. Blood 2000;96:398-404.
9. Lae ME, Ahmed I, Macon WR. Clusterin is widely expressed in systemic anaplastic large cell lymphoma but fails to differentiate primary from secondary cutaneous anaplastic large cell lymphoma. Am J Clin Pathol 2002;118:773-779.
10. Saffer H, Wahed A, Rassidakis GZ, et al. Clusterin expression in malignant lymphomas: a survey of 266 cases. Mod Pathol 2002;15:1221-1226.
11. Nascimento AF, Pinkus JL, Pinkus GS. Clusterin, a marker for anaplastic large cell lymphoma: immunohistochemical profile in hematopoietic and non-hematopoietic malignancies. Am J Clin Pathol 2004;121:709-717.
12. July LV, Akbari M, Zellweger T, et al. Clusterin expression is significantly enhanced in prostate cancer cells following androgen withdrawal therapy. Prostate 2002;50:179-188.
13. Redondo M, Villar E, Torres-Munoz J, et al. Overexpression of clusterin in human breast carcinoma. Am J Pathol 2000;157:393-399.
14. Xie MJ, Motoo Y, Su SB, et al. Expression of clusterin in human pancreatic cancer. Pancreas 2002;25:234-238.
15. Perez-Ordonez B, Erlandson RA, Rosai J. Follicular dendritic cell tumor: report of 13 additional cases of a distinctive entity. Am J Surg Pathol 1996;20:944-955.
16. Lewis JT, Gaffney RL, Casey MB, et al. Inflammatory pseudotumor of the spleen associated with a clonal Epstein-Barr virus genome. Am J Clin Pathol 2003;120:56-61.
17. Chan JKC, Fletcher CD, Nayler SJ, et al. Follicular dendritic cell sarcoma: clinicopathologic analysis of 17 cases suggesting a malignant potential higher than currently recognized. Cancer 1997;79:294-313.
18. Cheuk W, Chan JKC, Shek TWH, et al. Inflammatory pseudotumor-like follicular dendritic cell tumor. A distinctive low-grade malignant intra-abdominal neoplasm with consistent Epstein-Barr virus association. Am J Surg Pathol 2001;25:721-731.
19. Jones SE, Jomary C. Clusterin. Int J Biochem Cell Biol 2002;34:427-431.
20. Koch-Brandt C, Morgans C. Clusterin: a role in cell survival in the face of apoptosis? Prog Mol Subcell Biol 1996;16:130-149.
21. French LE, Sappino AP, Tschopp J, et al. Distinct sites of production and deposition of the putative cell death marker clusterin in the human thymus. J Clin Invest 1992;90:1919-1925.
22. Nielsen CH, Fischer EM, Leslie RGQ. The role of complement in the acquired immune response. Immunology 2000;100:4-12.