Treatment of hepatitis D

Journal of Viral Hepatitis

Volumn 12, Issue 1, 2005, Pages 2-9

  Niro, Grazia Anna ^a   Rosina, F ^b   Rizzetto, M ^c  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^b GRADENIGO HOSPITAL   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

HBV; HDV; Interferon; Lamivudine; Prenylation inhibitors; Transplantation

Indexed keywords

ACICLOVIR; ALPHA2B INTERFERON; DEOXYRIBONUCLEOTIDE; FAMCICLOVIR; HEPATITIS B SURFACE ANTIGEN; INTERFERON; LAMIVUDINE; PEGINTERFERON; RIBAVIRIN; SURAMIN; THYMOSIN;

ANTIVIRAL ACTIVITY; CHRONIC HEPATITIS; DELTA AGENT HEPATITIS; DISEASE ACTIVITY; ENZYME ACTIVITY; HUMAN; INFECTION RISK; LIVER TRANSPLANTATION; PRENYLATION; PRIORITY JOURNAL; REVIEW; SEROCONVERSION; VIRUS CARRIER; VIRUS REPLICATION;

CLINICAL TRIALS; HEPATITIS D; HUMANS; INTERFERONS; LIVER TRANSPLANTATION;

EID: 13244291672     PISSN: 13520504     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2005.00601.x     Document Type: Review

References (56)

1. Gaeta GB, Stornaiuolo G, Precone DF. Type B and D viral hepatitis: epidemiological changes in Southern Europe. Forum (Genova).
2. Sharmeen L, Kuo MY, Dinter-Gottlieb G, Taylor J. Antigenomic RNA of human hepatitis delta virus can undergo self-cleavage. J Virol 1988; 62: 2674-2679.
3. Hedin G, Weiland O, Ljunggren K et al. Treatment of fulminant hepatitis B and fulminant hepatitis B and D co-infection with foscarnet. In: Rizzetto M, Gerin JL, Purcell RH, eds. The Hepatitis Delta Virus and its Infection. New York: Alan R Liss, 1987: 309-320.
4. Rasshofer R, Choi S-S, Wolfl P, Roggendorf M. Interference of antiviral substances with replication of hepatitis delta virus RNA in primary woodchuck hepatocytes. Prog Clin Biol Res 1991; 364: 223-234.
5. Sanchez-Tapias JM, Mas A, Costa J et al. Recombinant alpha 2c-interferon therapy in fulminant viral hepatitis. J Hepatol 1987; 5(2): 205-210.
6. Arrigoni A, Ponzetto A, Actis GC, Bonino F. Levamisole and chronic delta hepatitis. Ann Intern Med 1983; 98: 1024.
7. Rizzetto M, Verme G, Recchia S et al. Chronic HBsAg hepatitis with intrahepatic expression of delta antigen. An active and progressive disease unresponsive to immunosuppressive treatment. Ann Intern Med 1983; 98: 437-441.
8. Di Bisceglie AM, Martin P, Lisker-Melman M et al. Treatment of chronic delta hepatitis with interferon alfa-2b: pilot study conducted at NIH. J Hepatol 1990; 11: S151-S154.
9. Farci P, Karayiannis P, Brook MG et al. Treatment of chronic hepatitis delta virus (HDV) infection with human lymphoblastoid alpha interferon. Quart J Med 1989; 73: 1045-1054.
10. Rosina F, Saracco G, Sansalvadore F et al. Alpha interferon in the treatment of chronic delta hepatitis. Ital J Gastroenterol 1989; 21: 141-145.
11. Farci P, Mandas A, Coiana A et al. Treatment of chronic hepatitis D with interferon alpha-2a. N Engl J Med 1994; 330: 88-94.
12. Madejon A, Cotonat T, Bartolome J et al. Treatment of chronic hepatitis D virus infection with low and high doses of interferon-alpha 2a: utility of polymerase chain reaction in monitoring antiviral response. Hepatology 1994; 19(6): 1331-1336.
13. Borghesio E. Rosina F, Di Marco V et al. Long term treatment of chronic hepatitis D with lymphoblastoid interferon: 10 MU vs 5 MU. An interim report of a randomized controlled trial. Hepatology 1995; 22: 397A.
14. Battegay M, Simpson LH, Hoofnagle JH et al. Elimination of hepatitis delta virus infection after loss of hepatitis B surface antigen in patients with chronic delta hepatitis. J Med Virol 1994; 44: 389-392.
15. Lau JY, King R, Tibbs CJ et al. Loss of HBsAg with interferon alpha therapy in chronic hepatitis D virus infection. J Med Virol 1993; 39: 292-296.
16. Rosina F, Marzano A, Garripoli A et al. Chronic type D hepatitis: clearance of hepatitis B surface antigen during and after treatment with alfa interferon. Hepatology 1990; 12: 883.
17. Lau DT, Kleiner DE, Park Y et al. Resolution of chronic delta hepatitis after 12 years of interferon alfa therapy. Gastroenterology 1999; 117(5): 1229-1233.
18. Kleiner D, Di Bisceglie AM, Axiotis CA, Hoofnagle JH. Prolonged alpha interferon therapy for chronic delta hepatitis: effect on liver histopathology. Prog Clin Biol Res 1993; 382: 365-371.
19. Berk L, Man RA, Housset C et al. Interferon combination therapy for chronic hepatitis type D. In: Gerin JL, Purcell RH, Rizzetto M, eds. The Hepatitis Delta Virus. New York: Wiley-Liss, 1991: 411-420.
20. Marinucci G, Hassan G, Di Giacomo C et al. Long term treatment of chronic delta hepatitis with alpha recombinant interferon. In: Gerin JL, Purcell RH, Rizzetto M, eds. The Hepatitis Delta Virus. New York: Wiley-Liss, 1991: 405-410.
21. Gaudin JL, Faure P, Codinot H et al. The French experience of treatment of chronic type D hepatitis with a 12 month course of IFN alpha-2b. Results of a randomized, controlled trial. Liver 1995; 15: 45-52.
22. Rumi MG, Del Ninno E, Romeo R et al. Long-term course of IFN alpha 2b treatment in chronic hepatitis delta. Abstracts from the Fifth International Symposium on Hepatitis Delta Virus and Liver Disease, Gold Coast, Australia, D46, 1995.
23. Rosina F, Pintus C, Meschievitz C, Rizzetto M. A randomized controlled trial of a 12 month course of recombinant human interferon alpha in chronic delta (type D) hepatitis: a multicenter Italian study. Hepatology 1991; 13: 1052-1056.
24. Crosignani A, Invernizzi P, Ferrari R et al. Exacerbation of chronic hepatitis D during interferon alpha administration. Ital J Gastroenterol Hepatol 1999; 31(1): 66-69.
25. Todros L, Touscoz G, D'Urso N et al. Hepatitis C virus-related chronic liver disease with autoantibodies to liver-kidney microsomes (LKM). J Hepatol 1991; 13: 128-131.
26. Rossetti F, Pontini F, Crivellaro C. Interferon therapy of chronic delta hepatitis in patients cured of pediatric malignancies: possible harmful effect. Liver 1991; 11: 255-259.
27. Craxi A, DiMarco V, Volpes R et al. Treatment with interferon alpha 2b of chronic HDV hepatitis in children. J Hepatol 1990; 11: 5175.
28. Smedile A, Rosina F, Saracco G et al. Hepatitis B virus replication modulates pathogenesis of hepatitis D virus in chronic hepatitis D. Hepatology 1991; 13: 413-416.
29. Marzano A, Ottobrelli A, Spezia C et al. Treatment of early chronic delta hepatitis with lymphoblastoid alpha interferon: a pilot study. Ital J Gastroenterol 1992; 24: 119-121.
30. Buti M, Esteban R, Roget M et al. Long term treatment with recombinant alpha 2 interferon in patients with chronic delta hepatitis and human immunodeficiency antibodies. J Hepatol 1989; 9: 5131.
31. Puoti M, Rossi S, Forleo MA et al. Treatment of chronic hepatitis D with interferon alpha-2b in patients with human immunodeficiency virus infection. J Hepatol 1998; 29: 45-52.
32. Taillan B, Fuzibet JG, Vinti H et al. Interferon and delta hepatitis. Ann Intern Med 1988; 109: 760 (letter).
33. McNair ANB, Cheng D, Monjardino J et al. Hepatitis delta virus replication in vitro is not affected by interferon alpha or gamma despite intact cellular responses to interferon and dsRNA. J Gen Virol 1994; 75: 1371-1378.
34. Ilan Y, Klein A, Taylor J, Tur-Kaspa R. Resistance of hepatitis delta virus replication to Interferon alpha treatment in transfected human cells. J Infect Dis 1992; 166: 1164-1166.
35. Ottobrelli A, Marzano A, Smedile A et al. Patterns of hepatitis delta virus reinfection and disease in liver transplantation. Gastroenterology 1991; 101: 1649-1655.
36. Deny P, Le Gal F, Poinsot H et al. Hepatitis D genetic heterogeneity in patients treated with high dose of alpha 2b interferon. Abstracts from the Fifth International Symposium on Hepatitis Delta Virus and Liver Disease, Gold Coast, Australia, D16, 1995.
37. Garripoli A, Di Marco V, Cozzolongo R et al. Ribavirin treatment for chronic hepatitis D: a pilot study. Liver 1994; 14: 154-157.
38. Buti M, Esteban R, Jardi R. Ribavirin therapy in chronic delta hepatitis. In: Taylor J, Bonino F, Hadziyannis S, eds. Hepatitis Delta Virus: Molecular Biology, Pathogenesis and Clinical Aspects. New York: Wiley-Liss, 1993: 468.
39. Rosina F, Conoscitore P, Giuliani A et al. Treatment of chronic hepatitis D with the thymosin derivative THF γ 2: results of pilot study. Hepatology 1994; 20: 309.
40. Rosina F, Conoscitore P, Smedile A et al. Treatment of chronic hepatitis D with thymus-derived polipeptide thymic humoral factor-gamma 2: a pilot study. Digest Liver Dis 2002; 34: 285-289.
41. Yurdaydin C, Bozkaya H, Gurel S et al. Famciclovir treatment of chronic delta hepatitis. J Hepatol 2002; 37(2): 266-271.
42. Lau DT, Doo E, Park Y et al. Lamivudine for chronic delta hepatitis. Hepatology 1999; 30: 546-549.
43. Andreone P, Spertini F, Negro F. Lamivudine-associated remission of chronic hepatitis delta. Ann Intern Med 2000; 132: 598.
44. Niro GA, Lagget M, Tillman HL et al. Efficacy of lamivudine therapy in chronic delta hepatitis: a multicenter randomized controlled pilot study. J Hepatol 2003; 38(2): 159A.
45. Wolters LM, van Nunen AB, Honkoop P et al. Lamivudine-high dose interferon combination therapy for chronic hepatitis B patients co-infected with the hepatitis D virus. J Viral Hepat 2000; 7(6): 428-434.
46. Chia JS, Wu HL, Wang HW et al. Inhibition of hepatitis delta virus genomic ribozyme self-cleavage by aminoglycosides. J Biomed Sci 1997; 4(5): 208-216.
47. Chen TZ, Wu JC, Au LC, Choo KB. Specific inhibition of delta antigen by in vitro system by antisense oligodeoxynucleotide: implications for translation mechanism and treatment. J Virol Methods 1997; 65(2): 183-189.
48. Bordier BB, Ohkanda J, Liu P et al. In vivo antiviral efficacy of prenylation inhibitors against hepatitis delta virus. J Clin Invest 2003; 112: 407-414.
49. Reynes M, Zignego L, Samuel D et al. Graft hepatitis delta virus reinfection after orthotopic liver transplantation in HDV cirrhosis. Transplant Proc 1989; 21: 2424-2425.
50. Bettale G, Alberti A, Belli LS et al. Recurrence of HDV infection after liver transplantation. Prog Clin Biol Res 1993; 382: 403-407.
51. Samuel D, Zignego AL, Reynes M et al. Long-term clinical and virological outcome after liver transplantation for cirrhosis caused by chronic delta hepatitis. Hepatology 1995; 21: 333-339.
52. David E, Rahier J, Pucci A et al. Recurrence of hepatitis D (delta) in liver transplants: histopathological aspects. Gastroenterology 1993; 104: 1122-1128.
53. Kaplan MM. Current concepts: acute fatty liver of pregnancy. N Engl J Med 1985; 313: 367-370.
54. Bove KE, McAdams AJ, Partin JC et al. The hepatic lesions in Reye's syndrome. Gastroenterology 1975; 69: 695-697.
55. Zimmerman HJ, Ishak KG. Valproate induced hepatic injury. Analysis of 23 fatal cases. Hepatology 1982; 2: 591-597.
56. Popper H, Thung SN, Gerber MA et al. Histologic studies of severe delta agent infection in Venezuelan Indians. Hepatology 1983; 6: 906-912.