Delayed extraction experiments using a repulsing potential before ion extraction: Evidence of non-covalent clusters as ion precursor in UV matrix-assisted laser desorption/ionization. Part II - Dynamic effects with α-cyano-4-hydroxycinnamic acid matrix

Journal of Mass Spectrometry

Volumn 40, Issue 1, 2005, Pages 50-59

  Fournier, I ^a,b   Brunot, A ^a   Tabet, J C ^a   Bolbach, G ^a  

^a SORBONNE UNIVERSITÉ   (France)

^b UNIV LILLE   (France)

Author keywords

Ablation; Ion formation; Matrix assisted laser desorption ionization; Mechanisms; Time of flight mass spectrometry

Indexed keywords

DESORPTION; EXTRACTION; IONIZATION; IONS; KINETIC ENERGY; LASER BEAM EFFECTS; ORGANIC SOLVENTS;

2,5-DIHYDROXYBENZOIC (2,5-DHB) MATRIX; MATRIX Α-CYANO-4-HYDROXYCINNAMICC ACID (HCCA); MATRIX-ASSISTED LASER DESORPTION; TIME-OF-FLIGHT VARIATIONS;

CARBOXYLIC ACIDS;

ALPHA CYANO 4 HYDROXYCINNAMIC ACID; BOVINE INSULIN; CORTICOTROPIN DERIVATIVE; CORTICOTROPIN[7-38]; ION; UNCLASSIFIED DRUG;

ARTICLE; DELAYED EXTRACTION; DESOLVATION; ELECTRIC FIELD; ENERGY; EXPERIMENT; ION PAIR EXTRACTION; IONIZATION; KINETIC ENERGY; MASS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MODEL; MOLECULAR WEIGHT; PRECURSOR; PRIORITY JOURNAL; REPULSING POTENTIAL; SOLVATION; ULTRAVIOLET SPECTROSCOPY; VELOCITY;

COUMARIC ACIDS; IONS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BOVINAE;

EID: 13244283457     PISSN: 10765174     EISSN: None     Source Type: Journal    
DOI: 10.1002/jms.772     Document Type: Article

References (27)

1. Fournier I, Brunot A, Tabet JC, Bolbach G. Delayed extraction experiments using a repulsive potential before ion extraction: evidence of clusters as ion precursors in UV-MALDI. Part I: dynamical effects with the matrix 2,5-dihydroxybenzoic acid. Int. J. Mass Spectrom. 2002; 213: 203.
2. Zenobi R, Knochenmuss R. Ion formation in MALDI mass spectrometry. Mass Spectrom. Rev. 1998; 17: 337.
3. Karas M, Glückmann M, Schäfer J. Ionization in matrix-assisted laser desorption/ionization: singly charged molecular ions are the lucky survivors. J. Mass Spectrom. 2000; 35: 1.
4. Spengler B. Post source decay analysis in matrix-assisted laser desorption/ionization mass spectrometry of biomolecules. J. Mass Spectrom. 1997; 32: 1019.
5. Dahl DA, SIMION 3D v6.0T Software. In Proceedings of the 43rd ASMS Conference on Mass Spectrometry and Allied Topics, Alberta, 1995; 217.
6. Juhasz P, Vestal ML, Martin SA. On the initial velocity of ions generated by matrix-assisted laser desorption/ionisation and its effect on the calibration of delayed extraction time-of-flight mass spectra. J. Am. Soc. Mass Spectrom. 1997; 8: 209.
7. Kinsel GR, Edmondson RD, Russel DH. Profile and flight-time analysis of bovine insulin clusters as a probe of matrix-assisted laser desorption/ ionization ion formation dynamics. J. Mass Spectrom. 1997; 32: 714.
8. Livadaris V, Blais JC, Tabet JC. Formation of non-specific protein cluster ions in matrix-assisted laser desorption/ionization: abundances and dynamical aspects. Eur. J. Mass Spectrom. 2000; 6: 409.
9. Haisa M, Kashimo S, Hanada K, Tanaka K, Okazaki S, Shibagaki M. The structure of 2-hydroxy-5-methylbenzoic acid and dimorphs of 2,5-dihydroxybenzoic acid. Acta Crystallogr., Sect. B 1982; 38: 1480.
10. Fournier I, Glückmann M, Karas M. Investigation of the MALDI process studying large crystal of MALDI matrices. Presented at the 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago, 2001.
11. Karbach V, Knochenmuss R, Zenobi R. Matrix-assisted filament desorption/ionization mass spectrometry. J. Am. Soc. Mass Spectrom. 1998; 9: 1226.
12. Zubarev RA, Bondarenko PV, Knysh AN, Rozynov BV. Electron avalanche desorption: a new soft ionisation technique for non volatile thermally labile molecules. Rapid Commun. Mass Spectrom. 1991; 5: 32.
13. Zhigilei LV, Kodali PBS, Garrison BJA. Microscopic view of laser ablation. J. Phys. Chem. B 1997; 101: 2028.
14. Zhigilei LV, Garrison BJ. Molecular dynamics simulation study of the plume dependence of particle yield and plume composition in laser desorption and ablation of organic solids. Appl. Phys. Lett. 1999; 74: 1341.
15. Zhigilei LV, Garrison BJ. Mechanisms of laser ablation from molecular dynamics. Dependence on the initial temperature and pulse duration. Appl. Phys. A 1999; 69: S75.
16. Dreisewerd K, Menzel C, Rohlfing A, Hillenkamp F, Kukreja LM. Photoacoustic analysis of the desorption process in IR-MALDI-MS. Presented at the 48th ASMS Conference on Mass Spectrometry and Allied Topics, Long Beach, 2000.
17. Allwood A, Dyer PE, Dreyfus RW. Ionization modelling of matrix molecules in ultraviolet matrix-assisted laser desorption/ionization. Rapid Commun. Mass Spectrom. 1997; 11: 499.
18. Karbach V, Knochenmuss R. Do single matrix molecules generate primary ions in ultraviolet matrix-assisted laser desorption ionization. Rapid Commun. Mass Spectrom. 1998; 12: 968.
19. Dreisewerd K, Schürenberg M, Karas M, Hillenkamp F. Influence of the laser intensity and spot size on the desorption of molecules and ions in matrix-assisted laser desorption/ionization with a uniform beam profile. Int. J. Mass Spectrom. Ion Processes 1995; 141: 127.
20. Fournier I, Marinach C, Tabet JC, Bolbach G. Irradiation effects in MALDI, ablation, ion production and surface modifications. Part II: 2,5-dihydroxybenzoic acid monocrystals. J. Am. Soc. Mass Spectrom. 2003; 14: 893.
21. Tang X, Sadeghi M, Olumee Z, Vertes A. Matrix assisted laser desorption ionization by two collinear subthreshold laser pulses. Rapid Commun. Mass Spectrom. 1997; 11: 484.
22. Knochenmuss R, Vertes A. Time delayed 2-pulse studies of MALDI matrix ionization mechanisms. J. Phys. Chem. B 2000; 104: 5406.
23. Land CM, Kinsel GR. Investigation of the mechanism of intracluster proton transfer from sinapinic acid to biomolecular analyte. J. Am. Soc. Mass Spectrom. 1998; 9: 1060.
24. Knochenmuss R. A quantitative model of ultraviolet matrix-assisted laser desorption/ionization. J. Mass Spectrom. 2002; 37: 867.
25. Kebarle P. Equilibrium studies of the solvated proton by high pressure mass spectrometry. Thermodynamic determinations and implications for the electrospray process. J. Mass Spectrom. 1997; 32: 922.
26. Meot-Ner M, Elmore DE, Scheiner S. Ionic hydrogen bond effects on the acidities, basicities, solvation, solvent bridging and self-assembly of carboxylic groups. J. Am. Chem. Soc. 1999; 121: 7625.
27. Alves S, Wind F, Alfonso C, Fournier F, Tabet JC. Role of cluster size on formation of detectable multiply charged ions during the MALDI ionization step. Presented at the 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago, 2001.