The acetylcholinesterase inhibitor BW284c51 is a potent blocker of Torpedo nicotinic AchRs incorporated into the Xenopus oocyte membrane

British Journal of Pharmacology

Volumn 144, Issue 1, 2005, Pages 88-97

  Olivera Bravo, Silvia ^a,b   Ivorra, Isabel ^a   Morales, Andrés ^a  

^a UNIVERSITY OF ALICANTE   (Spain)

^b Molecular Neuroscience Unit   (Uruguay)

Author keywords

Acetylcholine; BW284c51; Carbamylcholine; Cholinesterase inhibitors; Nicotinic acetylcholine receptors; Torpedo marmorata; Xenopus oocytes

Indexed keywords

1,5 BIS(4 ALLYLDIMETHYLAMMONIUMPHENYL)PENTAN 3 ONE DIBROMIDE; CARBACHOL; CHOLINESTERASE INHIBITOR; MUSCARINIC RECEPTOR; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; TACRINE; TUBOCURARINE CHLORIDE;

ANIMAL CELL; ARTICLE; CELL MEMBRANE CONDUCTANCE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; HYPERPOLARIZATION; MEMBRANE CURRENT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; TORPEDO MARMORATA; VOLTAGE CLAMP; XENOPUS LAEVIS;

ACETYLCHOLINE; ANIMALS; BENZENAMINIUM, 4,4'-(3-OXO-1,5-PENTANEDIYL)BIS(N,N-DIMETHYL-N-2-PROPENYL-), DIBROMIDE; CARBACHOL; CELL MEMBRANE; CHOLINERGIC AGENTS; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC CONDUCTIVITY; FEMALE; INHIBITORY CONCENTRATION 50; KINETICS; MEMBRANE PROTEINS; MICROINJECTIONS; MOLECULAR STRUCTURE; NEUROTRANSMITTER AGENTS; NICOTINIC ANTAGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; RECEPTORS, MUSCARINIC; RECEPTORS, NICOTINIC; TACRINE; TORPEDO; XENOPUS;

EID: 13244279430     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705965     Document Type: Article

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