Immune reconstitution: The major barrier to successful stem cell transplantation

Biology of Blood and Marrow Transplantation

Volumn 11, Issue 2 SUPPL. 2, 2005, Pages 43-45

  Antin, Joseph H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

GVHD; Immunity; Infection

Indexed keywords

IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G4; IMMUNOSUPPRESSIVE AGENT; MAJOR HISTOCOMPATIBILITY ANTIGEN; MINOR HISTOCOMPATIBILITY ANTIGEN; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TOLL LIKE RECEPTOR;

ALLOTRANSPLANTATION; ANTIGEN RECOGNITION; ARTICLE; B LYMPHOCYTE; BONE MARROW; CAUSE OF DEATH; CELLULAR IMMUNITY; DONOR; GRAFT VERSUS HOST REACTION; GRANULOCYTE FUNCTION; HELPER CELL; HLA MATCHING; HOMEOSTASIS; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENCE; IMMUNOGLOBULIN PRODUCTION; INFECTION; INFECTION RISK; INFLAMMATION; INNATE IMMUNITY; LYMPHOCYTE COUNT; LYMPHOCYTE FUNCTION; MONOCYTE; NATURAL KILLER CELL; OPPORTUNISTIC INFECTION; RELAPSE; STEM CELL TRANSPLANTATION; T LYMPHOCYTE; THYMUS FUNCTION; VACCINATION;

GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNE SYSTEM; REGENERATION;

EID: 13244277479     PISSN: 10838791     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbmt.2004.11.010     Document Type: Article

References (15)

1. C. Keever-Taylor Immune reconstitution after allogeneic transplantation. In: R.J. Soiffer (Ed.). Stem Cell Transplantation for Hematologic Malignancies 2004 Humana Press Totowa, NJ 201-236
2. J. Storek R.P. Witherspoon Immunological reconstitution after hemopoietic stem cell transplantation. In: K. Atkinson R. Champlin J. Ritz W.E. Fibbe P. Ljungman M. Brenner (Eds.). Clinical Bone Marrow and Blood Stem Cell Transplantation Third Edition 2004 Cambridge University Press New York 194-226
3. J. Storek M.A. Dawson D.G. Maloney Correlation between the numbers of naive T cells infused with blood stem cell allografts and the counts of naive T cells after transplantation Biol Blood Marrow Transplant. 9 2003 781-784
4. J. Storek M.A. Dawson B. Storer et al. Immune reconstitution after allogeneic marrow transplantation compared with blood stem cell transplantation Blood 97 2001 3380-3389
5. E. Vance S. George E.C. Guinan et al. Comparison of multiple immunization schedules for Haemophilus influenzae type b-conjugate and tetanus toxoid vaccines following bone marrow transplantation Bone Marrow Transplant. 22 1998 735-741
6. E.C. Guinan D.C. Molrine J.H. Antin et al. Polysaccharide conjugate vaccine responses in bone marrow transplant patients Transplantation 57 1994 677-684
7. J. Storek A. Joseph G. Espino et al. Immunity of patients surviving 20 to 30 years after allogeneic or syngeneic bone marrow transplantation Blood 98 2001 3505-3512
8. A.J. Mitus R. Stein J.M. Rappeport et al. Monoclonal and oligoclonal gammopathy after bone marrow transplantation Blood 74 1989 2764-2768
9. K.S. Peggs S. Verfuerth S. D'Sa K. Yong S. Mackinnon Assessing diversity: Immune reconstitution and T-cell receptor BV spectratype analysis following stem cell transplantation Br J Haematol. 120 2003 154-165
10. T.N. Small E.B. Papadopoulos F. Boulad et al. Comparison of immune reconstitution after unrelated and related T-cell-depleted bone marrow transplantation: Effect of patient age and donor leukocyte infusions Blood 93 1999 467-480
11. F. Aversa A. Tabilio A. Velardi et al. Treatment of high-risk acute leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype N Engl J Med. 339 1998 1186-1193
12. I. Volpi K. Perruccio A. Tosti et al. Postgrafting administration of granulocyte colony-stimulating factor impairs functional immune recovery in recipients of human leukocyte antigen haplotype-mismatched hematopoietic transplants Blood 97 2001 2514-2521
13. J.F. Sheridan P.J. Tutschka D.D. Sedmak E.A. Copelan Immunoglobulin G subclass deficiency and pneumococcal infection after allogeneic bone marrow transplantation Blood 75 1990 1583-1586
14. B.B. Blazar A. Panoskaltsis-Mortari B.B. Levine et al. The role of CD4+CD25+ T regulatory (Treg) cells in allogeneic bone marrow transplantation Biol Blood Marrow Transplant. 10 2004 737
15. J. Storek T. Gillespy III H. Lu et al. Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys Blood 101 2003 4209-4218