Actinophyllic acid, a potent indole alkaloid inhibitor of the coupled enzyme assay carboxypeptidase U/hippuricase from the leaves of Alatonia actinophylla (Apocynaceae)

Journal of Organic Chemistry

Volumn 70, Issue 3, 2005, Pages 1096-1099

  Carroll, Anthony R ^a   Hyde, Edward ^a   Smith, Jill ^a   Quinn, Ronald J ^a   Guymer, Gordon ^b   Forster, Paul I ^b  

^a GRIFFITH UNIVERSITY   (Australia)

^b QUEENSLAND HERBARIUM   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; ENZYME INHIBITION; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE;

ACTINOPHYLLIC ACID; AQUEOUS EXTRACTS; ENZYME ASSAYS;

CARBOXYLIC ACIDS;

ACTINOPHYLLIC ACID; AMINOACYLASE; FIBRINOLYTIC AGENT; INDOLE ALKALOID; PLANT EXTRACT; THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR; UNCLASSIFIED DRUG;

ALSTONIA; ARTICLE; BIOASSAY; CHROMATOGRAPHY; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; ENZYME ASSAY; ENZYME INHIBITION; FRACTIONATION; NUCLEAR MAGNETIC RESONANCE; PLANT LEAF; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

ALSTONIA; AMIDOHYDROLASES; BIOLOGICAL ASSAY; CARBOXYPEPTIDASE U; ENZYME INHIBITORS; INDOLE ALKALOIDS; PLANT LEAVES;

EID: 13244268408     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048439n     Document Type: Article

References (5)

1. Leurs, J.; Nerme, V.; Sim, Y.; Hendriks, D. J. Thromb. Haemostasis 2004, 2, 416-423.
2. Schatteman, K.; Goossens, F. J.; Leurs, J.; Kasahara, Y.; Scharpe, S. S.; Hendriks, D. F. Clin. Chem. Lab. Med. 2001, 39, 806-810.
3. Pretch, P. D. E.; Clerc, T.; Seibl, J.; Simon, W. Tables of Spectra Data for Structure Determination of Organic Compounds, 2nd ed.;, Fresenius, W., Huber, J. F. K., Pungor, E., Rechnitz, G. A., Simon, W., West, T., Eds.; Springer-Verlag: Berlin, Germany, 1989.
4. Dictionary of Natural Products on CD-ROM, Version 12:2; Chapman and Hall: New York, 2004.
5. Misra, N.; Luthra, R.; Singh, K. L.; Kumar, S. In Comprehensive Natural Product Chemistry; Barton, D., Nakanishi, K., Editor in Chief; Elsevier: Oxford, UK, 1999; Vol. 4, pp 25-59.