Comparison of various culture modes for the production of rabies virus by Vero cells grown on microcarriers in a 2-l bioreactor

Enzyme and Microbial Technology

Volumn 36, Issue 4, 2005, Pages 514-519

  Trabelsi, Khaled ^a   Rourou, Samia ^a   Loukil, Houssem ^a   Majoul, Samy ^a   Kallel, Héla ^a  

^a PASTEUR INSTITUTE OF TUNIS   (Tunisia)

Author keywords

[No Author keywords available]

Indexed keywords

BIOREACTORS; DISEASES; ENZYMES; GLUCOSE; VACCINES; VIRUSES;

MULTIPLICITY OF INFECTION (MOI); PERFUSION; RECIRCULATION; VERO CELLS;

BATCH CELL CULTURE;

BOVINE SERUM ALBUMIN; GLUCOSE; RABIES VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BATCH FERMENTATION; BIOREACTOR; CELL COUNT; CELL DENSITY; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENCY; IMMUNIZATION; INTERMETHOD COMPARISON; MOUSE; NONHUMAN; RABIES VIRUS; REGULATORY MECHANISM; VERO CELL; VIROGENESIS; VIRUS CULTURE; VIRUS INFECTION; VIRUS STRAIN; VIRUS TITRATION;

BOVINAE; RABIES VIRUS;

EID: 13244267448     PISSN: 01410229     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.enzmictec.2004.11.008     Document Type: Article

References (23)

1. F.X. Meslin, D.B. Fishbein, and H.C. Matter Rationale and prospects for rabies elimination in developing countries Curr Trop Microbiol Immunol 187 1994 1 26
2. L. Martinez Global infectious disease surveillance Int J Infect Dis 4 2000 22210 22228
3. Z.F. Fu, B. Dietzschold, S.A. Plotkin, and C.E. Rupprecht Improved vaccines against rabies New generation vaccines 1997 Marcel Dekker New York p. 607-17
4. V. Yusibov, D.C. Hooper, C.E. Rupprecht, S.V. Spitsin, N. Fleysh, and R.B. Kean Expression in plants and immunogenicity of plant virus-based experimental rabies vaccine Vaccine 20 2002 3155 3164
5. F.X. Meslin, and M.M. Kaplan General considerations in the production of brain-tissue and purified chicken embryo vaccines for human use Laboratory techniques in rabies 1996 WHO Geneva, Switzerland p. 360-8
6. B. Montagnon, J.C. Vincent-Falquet, and B. Fanget Thousand liter scale microcarrier culture of Vero cells for killed polio virus vaccine Dev Biol Stand 55 1984 37 42
7. O. Kistner, P.N. Barrett, W. Mundt, M. Reiter, S. Schober-Bendixen, and F. Dorner Development of a mammalian cell (Vero)-derived candidate influenza virus vaccine Vaccine 16 1998 960 968
8. K. Sugawara, K. Nishiyama, Y. Ishikawa, M. Abe, K. Sonoda, and K. Komatsu Development of Vero cell-derived inactivated Japanese encephalitis vaccine Biologicals 30 2002 303 314
9. S. Morgeaux, N. Tordo, C. Gontier, and P. Perrin β-Propiolactone treatment impairs the biological activity of residual DNA from BHK-21 cells infected with rabies virus Vaccine 11 1993 82 90
10. J.S. Smith, P.A. Yager, and G.M. Baer A rapid tissue culture test for determining rabies neutralizing antibody Laboratory techniques in rabies 1973 WHO Geneva, Switzerland p. 354-7
11. L.A. Wilbur, and MF.A. Aubert The NIH test for potency Laboratory techniques in rabies 1996 WHO Geneva, Switzerland p. 360-8
12. J.M. Berry, N. Barnabé, K.M. Coombs, and M. Butler Production of reovirus type-1 and type-3 from Vero cells grown on solid and macroporous microcarriers Biotechnol Bioeng 62 1999 12 19
13. R.Z. Mendonça, S.J. Arrozio, M.M. Antoniazzi, JMC. Ferreira Jr., and C.A. Pereira Metabolic active-high density Vero cell culture on microcarriers following apoptosis prevention by galactose/glutamine feeding J Biotechnol 97 2002 13 22
14. R.Z. Mendonça, and C.A. Pereira High density Vero cell culture on microcarriers in a cell bioreactor Bioprocess Eng 12 1995 279 282
15. R.Z. Mendonça, and C.A. Pereira Cell metabolism and medium perfusion in Vero cell cultures on microcarriers in a bioreactor Bioprocess Eng 18 1998 213 218
16. L. Fabry, B. Baijot, E. D'Hondt, and M. Duchene High cell density microcarrier cell culture for viral vaccine production Advances in animal cell biology and technology for bioprocesses 1989 Butterworth p. 361-5
17. H. Kallel, A. Jouini, S. Majoul, and S. Rourou Evaluation of various serum and animal protein-free media for the production of a veterinary rabies vaccine in BHK-21 cells J Biotechnol 95 2002 195 204
18. H. Kallel, S. Rourou, S. Majoul, and H. Loukil A novel process for the production of a veterinary rabies vaccine in BHK-21 cells grown on microcarriers in a 20-l bioreactor Appl Microbiol Biotechnol 61 2003 441 446
19. S. Mercille, and B. Massie Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells Biotechnol Bioeng 44 1994 1140 1154
20. R.Z. Mendonça, L.M. Ioshimoto, Mendonça RMZ, M. De-Franco, Valentini EJG, and W. Beçak Preparation of human rabies vaccine in Vero cell culture using a microcarrier system Braz J Med Biol Res 26 1993 1305 1317
21. N.M. Frazzati-Gallina, R.L. Paoli, R.M. Mourao-Fuches, Jorge SAC, and C.A. Pereira Higher production of rabies virus in serum-free medium cell cultures on microcarriers J Biotechnol 92 2001 67 72
22. World Health Organization. Requirements for rabies vaccine (inactivated) for human use produced in continuous cell line. WHO Tech Rep Ser, 1987. p. 167-95.
23. World Health Organization. Requirements for the use of animal cells as in vitro substrates for the production of biologicals. WHO Tech Rep Ser, 1998. p. 20-53.