Protective effect of M3 receptor on H2O 2-induced apoptosis of rat myocardial cells in vitro

Yaoxue Xuebao

Volumn 39, Issue 11, 2004, Pages 887-891

  Liu, Yan ^a   Sun, Hong Li ^a   Wu, Hong ^a   Gao, Yan Hui ^a   Li, Hu Lun ^a   Yang, Bao Feng ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Calcium; Confocal microscope; Cultured myocyte; Hydrogen peroxide; in situ nick end labeling; M3 receptor

Indexed keywords

CALCIUM ION; CHOLINE; FAS ANTIGEN; HYDROGEN PEROXIDE; MUSCARINIC AGENT; MUSCARINIC M3 RECEPTOR; PROTEIN BCL 2; CALCIUM;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MICROSCOPY; MORPHOLOGY; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; ANIMAL; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; METABOLISM; NEWBORN; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD95; APOPTOSIS; CALCIUM; CELLS, CULTURED; CHOLINE; HYDROGEN PEROXIDE; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RECEPTOR, MUSCARINIC M3;

EID: 13244264840     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Sharov VG, Sabbah ILN, Shimoyama IL, et al. Evidence of cardiocyte apoptosis in myocardium of dogs with chronic heart failure [J]. Am J Pathol, 1996,148(1): 141-149.
2. Hirota H, Chen J, Beta UA, et al. Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress [J]. Cell, 1999,97(2):189-198.
3. Wang H, Han H, Zhang L, et al. Expression of multiple subtypes of muscarinic receptors and cellular distribution in the human heart [J]. Mol Pharmacol, 2001,59(5): 1029-1036.
4. + current [J]. Brit J Pharmacol, 1999,126(8):1725-1734.
5. 3 receptor agonist on rat and rabbit hearts [J]. Acta Pharm Sin, 2001, 36(2):84-87.
6. + channel [J]. J Membrane Biol, 1999,169(1):55-64.
7. Albright CD, Liu R, Bethea TC, et al. Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture [J]. FASEB J, 1996,10(4):510-516.
8. Dong DL, Sun JP, Chen QW, et al. Effects of Berberin on calcium concentration in single guinea-pig ventricular myocytes [J]. J Pharmacol Toxicol, 2000, 14(2):128-130.
9. Harsdorf RV, Li PF, Dietz R. Signaling pathways in reactive oxygen species- induced cardiomyocyte apoptosis [J]. Circulation, 1999,99(22):2934- 2941.
10. Schlapbach R, Fontana A. Differential activity of bcl-2 and ICE enzyme family protease inhibitors on Fas and puromycin-induced apoptosis of glioma cells [J]. Biochim Biophys Acta, 1997,1359(2):174-180.
11. Hale AJ, Smith CA, Sutherlan LC, et al. Apoptosis : molecular regulation of cell death [J]. Eur J Biochem, 1996,236(1):1-26.