Effect of budesonide and montelukast in asthmatic children exposed to relevant allergens

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 60, Issue 2, 2005, Pages 206-210

  Peroni, D ^a   Bodini, A ^a   Del Giudice, Miraglia M ^b   Loiacono, A ^c   Baraldi, E ^d   Boner, A L ^a   Piacentini, G ^a,e  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c Istituto Pio XII   (Italy)

^d UNIVERSITY OF PADOVA   (Italy)

^e Policlinico GB Rossi   (Italy)

Author keywords

Airway inflammation; Asthma; Leukotriene antagonist; Montelukast; Nitric oxide; Steroid

Indexed keywords

ALLERGEN; ANTIGEN; BUDESONIDE; HOUSE DUST ALLERGEN; LEUKOTRIENE RECEPTOR BLOCKING AGENT; METHACHOLINE; MONTELUKAST; NITRIC OXIDE; PLACEBO;

ADOLESCENT; ARTICLE; ASTHMA; BRONCHUS HYPERREACTIVITY; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DERMATOPHAGOIDES; DRUG EFFECT; DRUG EFFICACY; ENVIRONMENTAL EXPOSURE; EOSINOPHILIA; EXHALATION; FEMALE; HUMAN; LOW DRUG DOSE; LUNG FUNCTION; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RELAPSE; SECONDARY PREVENTION; SPUTUM ANALYSIS; TREATMENT OUTCOME;

ACETATES; ALLERGENS; ANTI-ASTHMATIC AGENTS; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; BRONCHIAL HYPERREACTIVITY; BRONCHOCONSTRICTOR AGENTS; BRONCHODILATOR AGENTS; BUDESONIDE; CHILD; EOSINOPHILS; EXHALATION; FEMALE; HUMANS; LUNG; MALE; METHACHOLINE CHLORIDE; NITRIC OXIDE; QUINOLINES; RESPIRATORY FUNCTION TESTS; SPUTUM;

EID: 13244259344     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2005.00670.x     Document Type: Article

References (26)

1. Piacentini GL, Bodini A, Costella S, Suzuki Y, Zerman L, Peterson CGB et al. Exhaled nitric oxide, serum ECP and airway responsiveness in mild asthmatic children. Eur Resp J 2000;15: 839-843.
2. Piacentini GL, Bodini A, Costella S, Vicentini L, Peroni DG, Zanolla L et al. Allergen avoidance is associated with a fall in exhaled nitric oxide in asthmatic children. J Allergy Clin Immunol 1999;104:1323-1324.
3. Piacentini GL, Bodini A, Costella S, Vicentini L, Mazzi P, Peroni DG et al. Exhaled NO in asthmatic children exposed to relevant allergens: effect of Flunisolide. Eur Resp J 2000;15: 730-734.
4. Piacentini GL, Peroni DG, Del Giudice MM, Bodini A, Costella S, Vicentini L et al. Effect of montelukast on exhaled NO in asthmatic children exposed to relevant allergens. Pediatr Allergy Immunol 2002;13:137-139.
5. Ghiro L, Zanconato S, Rampon O, Piovan V, Pasquale MF, Baraldi E. Effect of montelukast added to inhaled corticosteroids on fractional exhaled nitric oxide in asthmatic children. Eur Respir J 2002;20:630-634.
6. Warner JO. The role of leukotriene receptor antagonists in the treatment of chronic asthma in childhood. Allergy 2001;56(Suppl. 66):22-29.
7. Bisgaard H. Pathophysiology of the cysteinyl leukotrienes and effects of leukotriene receptor antagonists in asthma. Allergy 2001;56(Suppl. 66):7-11.
8. Becler K, Hakansson L, Rak S. Treatment of asthmatic patients with a cysteinyl leukotriene receptor-1 antagonist montelukast (Singulair), decreases the eosinophil survival-enhancing activity produced by peripheral blood mononuclear leukocytes in vitro. Allergy 2002;57: 1021-1028.
9. American Thoracic Society Committee on Diagnostic Standards for Nontubercolosis Respiratory Diseases. Definitions and classifications of chronic bronchitis, asthma and pulmonary emphysema. Am Rev Respir Dis 1962;85:762-768.
10. Baraldi E, DE Jongste J. European Respiratory Society/American Thoracic Society. Measurement of exhaled nitric oxide in children, 2001. Eur Respir J 2002;20:223-237.
11. Piacentini GL, Bodini A, Peroni DG, Miraglia del Giudice M Jr, Costella S, Boner AL. Reduction in exhaled nitric oxide immediately after methacholine challenge in asthmatic children. Thorax 2002;57:771-773.
12. Hargreave FE, Ryan G, Thomson NC. Bronchial responsiveness to histamine or methacholine in asthma: measurement and clinical significance. J Allergy Clin Immunol 1981;68:347-355.
13. Sterk PJ, Fabbri LM, Quanjer PH, Cockroft DW, O'Byrne PM, Aderson SD et al. Airway responsiveness. Standardised challenge testing with pharmacolological, physical and sensitizing stimuli in adults. Reeport Working Party of lung Function tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society. Eur Respir J 1993;16:53-83.
14. Gibson PG, Henry RL, Thomas P. Noninvasive assesment of airway inflammation in children: induced sputum, exhaled nitric oxide, and breath condensate. Eur Respir J 2000;16: 1008-1015.
15. Pin I, Gibson PG, Kolendowicz R, Girgis-Gabardo A, Denburg JA, Hargreave FE et al. Use of induction sputum cell counts to investigate airway inflammation in asthma. Thorax 1992;47:25-29.
16. Luczynska CM, Arruda LK, Platt-Mills TAE, Miller JD, Lopez M, Chapman MD. A two site monoclonal antibody ELISA for the quantitation of the major Dermatophagoides spp. allergens, Der p I and Der f I. J Immunol Methods 1989;118:227-235.
17. Platts-Mills TAE, Vervloet D, Thomas WR, Aalberse RC, Chapman MD. Indoor allergens and asthma: report of the third international workshop. J Allergy Clin Immunol 1997;100: S1-S23.
18. Bisgaard H, Loland L, Anhoj J. NO in exhaled air of asthmatic children is reduced by the leukotriene receptor antagonist montelukast. Am J Respir Crit Care Med 1999;160:1227-1231.
19. Bisgaard H. Leukotriene modifiers in pediatric asthma management. Pediatrics 2001;107:381-390.
20. Peroni DG, Piacentini GL, Ress M, Bodini A, Loiacono A, Aralla R et al. Time efficacy of a single dose of montelukast on exercise-induced asthma in children. Pediatr Allergy Immunol 2002;13:434-437.
21. Custivic A, Taggart SCO, Francis HC, Chapman MD, Woodcock A. Exposure to house dust mite allergens and clinical activity of asthma. J Allergy Clin Immunol 1996;98:64-72.
22. Crimi E, Spanavello A, Neri M, Ind PW, Rossi GA, Brusasco V. Dissociation between airway inflammation and airway hyperresponsiveness in allergic asthma. Am J Respir Crit Care Med 1998;157:4-9.
23. Mattes J, Strom van's Gravesande K, Reining U, Alving K, Ihorst G, Henschen M et al. NO in exhaled air is correlation with markers of eosinophilic airway inflammation in corticosteroid-dependent childhood asthma. Eur Respir J 1999;13:1391-1395.
24. Berlyne GS, Parameswara ChB, Kamada D, Efthimiadis A, Hargreave FE. A comparison of exhaled nitric oxide and induced sputum as markers of airway inflammation. J Allergy Clin Immunol 2000;106:638-644.
25. Piacentini GL, Bodini A, Costella S, Vicentini L, Mazzi P, Sperandio S et al. Exhaled nitric oxide and sputum eosinophil markers of inflammation in asthmatic children. Eur Resp J 1999;13:1386-1390.
26. Pizzichini E, Pizzichini MM, Gibson P, Parameswaran K, Gleich GJ, Herman L. Sputum eosinophilia predicts from prednisolone in smokers with chronic obstructive bronchitis. Am J Respir Crit Care Med 1998;158:1511-1517.