Should our approach to the anticardiolipin assay change 20 years after its discovery?

Journal of Thrombosis and Haemostasis

Volumn 2, Issue 7, 2004, Pages 1074-1076

  Meroni, Pier Luigi ^a   Tincani, A ^b  

^a UNIVERSITY OF MILAN   (Italy)

^b Rheumatology Service   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN C; ANTINUCLEAR ANTIBODY; AUTOANTIBODY; BETA2 GLYCOPROTEIN 1; BLOOD CLOTTING FACTOR 12; CARDIOLIPIN ANTIBODY; COMPLEMENT COMPONENT C4B; HIGH MOLECULAR WEIGHT KININOGEN; LIPOCORTIN 5; LUPUS ANTICOAGULANT; MITOCHONDRION ANTIBODY; PHOSPHOLIPID ANTIBODY; PLASMA PROTEIN; PROTEIN C; PROTEIN S; PROTHROMBIN ANTIBODY; THROMBOCYTE ANTIBODY; THROMBOMODULIN; THYROID ANTIBODY; TISSUE FACTOR PATHWAY INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR;

ANTIBODY DETECTION; ANTIPHOSPHOLIPID SYNDROME; AUTOIMMUNITY; BLOOD CLOTTING; CLINICAL FEATURE; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; ECONOMIC ASPECT; FETUS WASTAGE; HUMAN; IMMUNOASSAY; LABORATORY TEST; MORBIDITY; NOTE; PATIENT MONITORING; PREVALENCE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; SOCIAL ASPECT; THROMBOSIS; UNITED KINGDOM;

ANTIBODIES, ANTICARDIOLIPIN; ANTIPHOSPHOLIPID SYNDROME; AUTOANTIBODIES; HUMANS; SENSITIVITY AND SPECIFICITY; SEROLOGIC TESTS;

EID: 13244255285     PISSN: 15387933     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2004.00817.x     Document Type: Note

References (17)

1. Harris EN, Gharavi AE, Boey ML, Patel BM, Mackworth-Young CG, Loizou S, Hughes GR. Anticardiolipin antibodies: detection by radioimmunoassay and association with thrombosis in systemic lupus erythematosus. Lancet 1983; 2: 1211-4.
2. Wilson WA, Gharavi AE, Koike T, Lockshin D, Branch DW, Piette J-C, Brey R, Derksen R, Harris EN, Hughes GRV, Tripplet DA, Khamashta MA. International consensus statement on preliminary classification criteria for definite antiphospholipid syndrome. Arthritis Rheum 1999; 42 1309-11.
3. Shoenfeld Y. Systemic antiphospholipid syndrome. Lupus 2003; 12: 497-8.
4. Avcin T, Cimaz R, Meroni PL. Recent advances in antiphospholipid antibodies and antiphospholipid syndrome in pediatric populations. Lupus 2002; 11: 4-10.
5. Tincani A, Franceschini F, Spunghi M, Panzeri P, Balestrieri G, Meroni PL. Immunological abnormalities in the antiphospholipid syndrome in the antiphospholipid syndrome II. Autoimmune Thrombosis (Asherson RA, Cervera R, Piette JC. Shoenfeld Y. ed.), pp. 271. Amsterdam: Elsevier, 2002.
6. Tincani A, Gilburd B, Abu-Shakra M, Blank M, Allegri F, Ottaviani R, Riboni M, Meroni PL, Balestrieri G, Shoenfeld Y. Immunization of naive BALB/c mice with human beta2-glycoprotein I breaks tolerance to the murine molecule. Arthritis Rheum 2002; 46: 1399-404.
7. Gharavi AE, Pierangeli SS, Espinola RG, Liu X, Colden-Stanfield M, Harris EN. Antiphospholipid antibodies induced in mice by immunization with a cytomegalovirus-derived peptide cause thrombosis and activation of endothelial cells in vivo. Arthritis Rheum 2002; 46: 545-52.
8. Blank M, Krause I, Fridkin M, Keller N, Kopolovic J, Goldberg I, Tobar A, Shoenfeld Y. Bacterial induction of autoantibodies to β2-glycoprotein I accounts for the infectious etiology of antiphospholipid syndrome. J Clin Invest 2002; 109: 797-804.
9. Blank M, Asherson RA, Cervera R, Shoenfeld Y. Antiphospholipid syndrome infectious origin. J Clin Immunol 2004; 24: 12-23.
10. Vanderlugt CL, Miller SD. Epitope spreading in immune-mediated diseases: implications for immunotherapy. Nat Rev Immunol 2002; 2: 85-95.
11. Galli M, Luciani D, Bertolini G, Barbui T. Lupus anticoagulants are stronger risk factor of thrombosis than anticardiolipin antibodies in the antiphospholipid syndrome: a systematic review of the literature. Blood 2002; 101: 1827-32.
12. Reber G, Arvieux J, Comby E, Degenne D, de Moerloose P, Sanmarco M, Potron G. Multicenter evaluation of nine commercial kits for the quantitation of anticardiolipin antibodies. Thromb Haemost 1995; 73: 444-52.
13. Favaloro EJ, Silvestrini R. Assessing the usefulness of anticardiolipin antibody assays a cautious approach is suggested by high variation and limited consensus in multilaboratory testing. Am J Clin Path 2002; 118: 548-77.
14. Tincani A, Allegri F, Sanmarco M, Cinquini M, Taglietti M, Balestrieri G, Koike T, Ichikawa K, Meroni P, Boffa MC. Anticardiolipin antibody assay: a methodological analysis for a better consensus in routine determinations: a cooperative project of the European Antiphospholipid Forum. Thromb Haemost 2001; 86: 575-83.
15. Nash MJ, Camilleri RS, Kunka S, Mackie IJ, Machin S, Cohen H. The anticardiolipin assay is required for sensitive screening for antiphospholipid antibodies. J Thromb Haemost 2004, 2: 1077-81.
16. Solomon DH, Kavanaugh AJ, Schur PH, American College of Rheumatology Ad Hoc Committee on Immunologic Testing Guidelines. Evidence-based guidelines for the use of immunologic tests: antinuclear antibody testing. Arthritis Rheum 2002; 47: 434-44.
17. Cugno M, Cabibbe M, Galli M, Meroni PL, Caccia S, Russo R, Bottasso B, Mannucci PM. Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients. Blood 2004; 103: 2121-6.