Mitochondrial DNA analysis on remains of a putative son of Louis XVI, King of France and Marie-Antoinette

European Journal of Human Genetics

Volumn 6, Issue 4, 1998, Pages 383-395

  Jehaes, Els ^a   Decorte, Ronny ^a   Peneau, Alain ^b   Petrie, Johan H ^c   Boiry, Philippe A ^d   Gilissen, Anja ^a   Moisan, Jean Paul ^b   Van Den Berghe, Herman ^a   Pascal, Olivier ^b   Cassiman, Jean Jacques ^a,e  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b NANTES UNIVERSITY HOSPITAL   (France)

^c Petrus Campussingel   (Netherlands)

^d Faculte Libre des Sci de la Commun   (France)

^e UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Ancient DNA; Genetic identification; Louis XVII; Mitochondrial DNA

Indexed keywords

MITOCHONDRIAL DNA;

ARTICLE; BONE; CASE REPORT; DNA DETERMINATION; DNA SEQUENCE; FORENSIC IDENTIFICATION; HAIR; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; RELATIVE; SKELETON;

EID: 13144275279     PISSN: 10184813     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.ejhg.5200227     Document Type: Article

References (33)

1. Hagelberg E, Gray IC, Jeffreys AJ: Identification of the skeletal remains of a murder victim by DNA analysis. Nature 1991; 352: 427-429.
2. Gill P, Ivanov PL, Kimpton C et al: Identification of the remains of the Romanov family by DNA analysis. Nat Genet 1994; 6: 130-135.
3. Jeffreys AJ, Allen MJ, Hagelberg E, Sonnberg A: Identification of the skeletal remains of Josef Mengele by DNA analysis. Forensic Science Int 1992; 56: 65-76.
4. Aquadro CF, Greenberg BD: Human mitochondrial DNA variation and evolution: analysis of nucleotide sequences from seven individuals. Genetics 1983; 103: 287-312.
5. Orrego C, King MC: Determination of familial relationships. In: Innis MA, Gelfand DH, Sninsky JJ, White TJ (eds). PCR Protocols. Academic Press: London: 1990; pp 416-426.
6. Bogenhagen D, Clayton DA: The number of mitochondrial deoxyribonucleic acid genomes in mouse L and human HeLa cells. J Biol Chem 1974; 249: 7991-7995.
7. Rogan PK, Salvo JJ: Molecular genetics of pre-Columbian South American mummies. Yearbook of Physical Anthropology 1990; 33: 195-214.
8. Hagelberg E, Sykes B, Hedges R: Ancient bone amplified. Nature 1989; 342: 485.
9. Krings M, Stone A, Schmitz RW, Krainitzki H, Stoneking M, Pääbo S: Neanderthal DNA sequences and the origin of modern humans. Cell 1997; 90: 19-30.
10. Jehaes E, Gilissen A, Decorte R, Cassiman J-J: Evaluation of a decontamination protocol for hair shafts before mtDNA sequencing. Forensic Science Int. 1998.
11. Higuchi R, von Beroldingen CH, Sensabaugh GF, Erlich HA: DNA typing from single hairs. Nature 1988; 332: 543-546.
12. Höss M, Pääbo S: DNA extraction from pleistocene bones by a silica-based purification method. Nucleic Acids Res 1993; 21: 3913-3914.
13. Decorte R, Jehaes E, Xiao, FX, Cassiman J-J: Genetic analysis of single hair shafts by automated sequence analysis of the mitochondrial D-loop region. Adv For Haemogen 1996; 6: 17-20.
14. Jehaes E, Habex H, Decorte R, Charlier C, Van Den Berghe H, Cassiman J-J: Isolation and characterization of mitochondrial DNA from ancient remains; application to bone samples from the archaeological site at Erps-Kwerps. Acta Archaeologica Lovaniensia 1994; 33: 101-106.
15. Sanger F, Nicklen S, Coulson AR: DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci USA 1977; 74: 5463-5467.
16. Sullivan KM, Mannuci A, Kimpton CP, Gill P: A rapid and quantitative DNA sex test: Fluorescence-based PCR analysis of X-Y homologous gene amelogenin. Biotechniques 1993; 15: 100-119.
17. Decorte R, Cassiman J-J: Evaluation of the ALF DNA sequencer for high-speed sizing of short tandem repeat alleles. Electrophoresis 1996; 15: 1542-1549.
18. Parsons TJ, Muniec DS, Sullivan K et al: A high observed substitution rate in the human mitochondrial DNA control region. Nat Genet 1997; 15: 363-368.
19. Piercy R, Sullivan KM, Benson N, Gill P: The application of mitochondrial DNA typing to the study of white Caucasian identification. Int J Legal Med 1993; 106: 85-90.
20. Anderson S, Bankier AT, Barrel BG et al: Sequence and organization of the human mitochondrial genome. Nature 1981; 290: 457-465.
21. Kayser M, Caglia A, Corach D et al: Evolution of Y-chromosomal STRs: a multicenter study. Int J Legal Med 1997; 110: 125-133.
22. Eckert KA, Kunkel TA: DNA polymerase fidelity and the polymerase chain reaction. PCR Methods Appl 1991; 1: 17-24.
23. Ballinger SW, Schurr TG, Torroni A et al: Southeast Asian mitochondrial DNA analysis reveals genetic continuity of ancient Monogoloid migrations. Genetics 1992; 130: 139-152.
24. Greenberg BD, Newbold JE, Sugino A: Intraspecific nucleotide sequence variability surrounding the origin of replication in human mitochondrial DNA. Gene 1983; 21: 33-49.
25. Horai S, Hayasaka K: Intraspecific nucleotide sequence differences in the major noncoding region of human mitochondrial DNA. Am J Hum Genet 1990; 46: 828-842.
26. Horai S, Kondo R, Nakagawa-Hattori Y, Hayashi S, Sonoda S, Tajima K: Peopling of the Americas, founded by four major lineages of mitochondrial DNA. Mol Biol Evol 1993; 10: 23-47.
27. Wilson MR, Polanskey D, Butler J, DiZinno JA, Replogle J, Budowle B: Extraction, PCR amplification and sequencing of mitochondrial DNA from human hair shafts. Biotechniques 1995; 18: 662-669.
28. Torroni A, Sukernik RI, Schurr TG et al: Asian affinities and continental radiation of the four founding Native American mtDNAs. Am J Hum Genet 1993; 53: 563-559.
29. Torroni A, Sukernik RI, Schurr TG et al: mtDNA variation of aboriginal Siberians reveals distinct genetic affinities with Native Americans. Am J Hum Genet 1993; 53: 591-608.
30. Chen YS, Torroni A, Excoffier L, Santachiara-Benerecetti AS, Wallace DC: Analysis of mtDNA variation in African populations reveals the most ancient of all human continent-specific haplogroups. Am J Hum Genet 1995; 57: 133-149.
31. Torroni A, Huopen K, Francalacci P et al: Classification of European mtDNAs from an analysis of three European populations. Genetics 1996; 144: 1835-1850.
32. Aris-Brosou S, Excoffier L: The impact of population expansion and mutation rate heterogeneity on DNA sequence polymorphism. Mol Biol Evol 1996; 13: 494-504.
33. Petrie JH: Lodewijk XVII-Naundorff, een mysterie ontrafeld. De Bataafsche Leeuw: Amsterdam, 1995.