Prenatal ethanol exposure enhances glutamate release stimulated by quisqualate in rat cerebellar granule cell cultures

Molecular and Chemical Neuropathology

Volumn 33, Issue 2, 1998, Pages 99-111

  Rhodes, Philip G ^a   Cai, Zhengwei ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebellar granule cells; Ethanol exposure in utero; Exocytosis of glutamate; Metabotropic glutamate receptor; Quisqualate; t ACPD

Indexed keywords

1 AMINO 1,3 CYCLOPENTANEDICARBOXYLIC ACID; 6 CYANO 7 NITRO 2,3 QUINOXALINEDIONE; ALCOHOL; DIZOCILPINE; GLUTAMATE RECEPTOR AGONIST; GLUTAMIC ACID; KAINIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; QUISQUALIC ACID;

AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CEREBELLUM; EXOCYTOSIS; GRANULE CELL; IMMUNOBLOTTING; NEWBORN; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT;

EID: 13144265712     PISSN: 10447393     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02870184     Document Type: Article

References (41)

1. Balazs R. and Hack N. (1990) Trophic effects of excitatory amino acids in developing nervous system, in Excitatory Amino Acids and Plasticity (Ben Ari Y, ed.), pp. 221-228, Plenum, New York.
2. Bradford M. M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
3. Brose N., Thomas A., Weber M. G., and Jahn R. (1993) A chloride- and calcium-dependent glutamate binding protein from rat brain. J. Biol. Chem. 256, 10,604-10,610.
4. Burgoyne R. D., Graham M. E., and Cambray-Deakin M. (1993) Neurotrophic effects of NMDA receptor activation on developing cerebellar granule cells. J. Neurocytol. 22, 689-695.
5. Cai Z., Sigrest T., Hersey K., and Rhodes P. G. (1995) Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells. Pediatr. Res. 38, 107-112.
6. Cantania M. V., Aronica E., Sortino M. A., Canonico P. L., and Nicoletti F. (1991) Desensitization of metabotropic glutamate receptors in neuronal cultures. J. Neurochem. 56, 1329-1335.
7. Carboni S., Isola R., Gessa G. L., and Rossetti Z. L. (1993) Ethanol prevents the glutamate release induced by N-methyl-D-aspartate in the rat striatum. Neurosci. Lett. 152, 133-136.
8. Carmichael F. J. and Israel Y. (1975) Effects of ethanol on neurotransmitter release by rat brain cortical slices. J. Pharmacol. Exp. Ther. 193, 824-834.
9. Choi D. W. (1992) Excitotoxic cell death. J. Neurobiol. 23, 1261-1276.
10. Coffey E. T., Sihra T. S., and Nicholls D. G. (1993) Protein kinase C and the regulation of glutamate exocytosis from cerebrocortical synaptosomes. J. Biol. Chem. 268, 21,060-21,065.
11. Costa E., Fadda E., Kozikowski A. P., Nicoletti F., and Wroblewski J. T. (1988) Classification and allosteric modulation of excitatory amino acid signal transduction in brain slices and primary cultures of cerebèllar neurons, in Neurobiology of Amino Acids, Peptides and Trophic Factors (Collins J. and Johnson E., eds.), pp. 35-50, Nijhoff, Boston, MA.
12. 3H-glutamate binding in 45-day-old rats. Alcohol 5, 125-133.
13. 3H]-vinylidene kainic acid binding in 45-day-old rats. Neurotoxicol. Teratol. 10, 563-568.
14. Grant K. A., Knisely J. S., Tabakoff B., Barrett J. E., and Balster R. L. (1991) Ethanol-like descriminative stimulus effects of non-competitive N-methyl-D-aspartate antagonists. Behav. Pharmacol. 2, 87-95.
15. Gulya K., Grant K. A., Valverius P., Hoffman P. L., and Tabakoff B. (1991) Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal. Brain Res. 547, 129-134.
16. Herrero I., Miras-Portugal M. T., and Sanchez-Prieto J. (1992) Positive feedback of glutamate exocytosis by metabotropic presynaptic receptor stimulation. Nature 360, 163-166.
17. Hoffman P. L., Rabe C. S., Mosses F., and Tabakoff B. (1989) N-methyl-D-aspartate receptors and ethanol: inhibition of calcium flux and cyclic GMP production. J. Neurochem. 52, 1937-1940.
18. Honore T., Davis S. N., Drejer J., Fletcher E. J., Jacobsen P., Lodge D., and Nielsen F. E. (1988) Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science 241, 701-703.
19. Martin D. and Swartzwelder H. S. (1992) Ethanol inhibits release of excitatory amino acids from slices of hippocampal area CA1. Eur. J. Pharmacol. 219, 469-472.
20. McCaslin P. P. and Smith T. G. (1990) Low calcium-induced release of glutamate results in autotoxicity of cerebellar granule cells. Brain Res. 417, 280-285.
21. McDonald J. W. and Johnston M. V. (1990) Physiological and pathophysiological roles of excitatory amino acids during central nervous system development. Brain Res. Rev. 15, 41-70.
22. 2+ mobilization in rat hippocampal cells are mediated by protein kinase C. Brain Res. 714, 27-37.
23. Nicholls D. G. (1993) Ion channels and the regulation of neurotransmitter glutamate release. Biochem. Soc. Trans. 21, 53-58.
24. Noble E. P. and Ritchie T. (1989) Prenatal ethanol exposure reduces the effects of excitatory amino acids in the rat hippocampus. Life Sci. 45, 803-810.
25. Palmer E., Monahan D. T., and Cotman C. W. (1989) Trans-ACPD, a selective agonist of the phosphoinositide-coupled excitatory amino acid receptor. Eur. J. Pharmacol. 166, 585-587.
26. Queen S. A., Sanchez C. F., Lopez S. R., Paxton L. L., and Savage D. D. (1993) Dose and age-dependent effects of prenatal ethanol exposure on hippocampal metabotropicglutamate receptor-stimulated phosphoinositide hydrolysis. Alcohol Clin. Exp. Res. 17, 887-893.
27. Raulli R. and Wroblewski J. T. (1991) Stimulation of phosphoinositide hydrolysis by ibotenic acid in cerebellar neurons via two glutamate receptor subtypes. Drug Dev. Res. 24, 375-383.
28. Rawls S. M. and McGinty J. F. (1997) L-trans-pyrrolidine-2,4-dicarboxylic acid-evoked striatal glutamate levels are attenuated by calcium reduction, tetrodotoxin, and glutamate receptor blockade. J. Neurochem. 68, 1553-1563.
29. Reynolds J. D. and Brien J. F. (1994) Effects of acute ethanol exposure on glutamate release in the hippocampus of the fetal and adult guinea pig. Alcohol 11, 259-267.
30. Reynolds J. D. and Brien J. F. (1995) The role of adenosine A1 receptor activation in ethanol-induced inhibition of stimulated glutamate release in the hippocampus of the fetal and adult guinea pig. Alcohol 12, 151-157.
31. Rhodes P. G., Cai Z., and Zhu N. (1994) Prenatal ethanol exposure reduces phosphoinositide hydrolysis stimulated by quisqualate in rat cerebellar granule cell cultures. Mol. Chem. Neuropathol. 23, 65-76.
32. Rothman S. and Olney J. (1986) Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19, 105-111.
33. Sanchez-Prieto J., Herrero I., and Miras-Portugal M. T. (1993) Modulation of the exocytotic release of neurotransmitter glutamate by protein kinase C. Adv. Exp. Med. Biol. 341, 95-105.
34. 3H-glutamate binding site density in 45-day-old rats. Alcohol 8, 193-201.
35. Savage D. D., Queen S. A., Sanchez C. F., Paxton L. L., Mahoney J. C., Goodlett C. R., and West J. R. (1992) Prenatal ethanol exposure during the last third of gestation in rat reduces hippocampal NMDA agonist binding site density in 45-day-old offspring. Alcohol 9, 37-41.
36. Simson P. E., Criswell H. E., Johnson K. B., Hicks R. E., and Breese G. R. (1991) Ethanol inhibits NMDA-evoked electrophysiological activity in vivo. J. Pharmacol. Exp. Ther. 257, 225-231.
37. Sladeczek F., Recasens M., and Bockaert J. (1988) A new mechanism for glutamate receptor action: phosphoinositide hydrolysis. Trends Neurosci. 11, 545-549.
38. Snell L. D., Tabakoff B., and Hoffman P. L. (1994) Involvement of protein kinase C in ethanol-induced inhibition of NMDA receptor function in cerebellar granule cells. Alcohol Clin. Exp. Res. 18, 81-85.
39. Suzdak P. D., Thomsen C., Mulvihill E., and Kristensen P. (1994) Molecular cloning, expression and characterization of metabotropic glutamate receptor subtypes, in The Metabotropic Glutamate Receptors (Conn P. J. and Patel J., ed.), pp. 1-30, Humana, Totowa, NJ.
40. Trevisan L., Fitzgerald L. W., Brose N., Gasic G. P., Heinemann S. F., Duman R. S., and Nestler E. J. (1994) Chronic ingestion of ethanol up-regulates NMDAR1 receptor subunit immunoreactivity in rat hippocampus. J. Neurochem. 62, 1635-1638.
41. Trussell L. O., Zhang S., and Raman I. M. (1993) Desensitization of AMPA receptors upon multiquantal neurotransmitter release. Neuron 10, 1185-1196.