Dissociation equilibrium between uncharged and charged local anesthetic lidocaine in a surface-adsorbed film

Colloid and Polymer Science

Volumn 283, Issue 5, 2005, Pages 512-520

  Matsuki, Hitoshi ^a   Yamanaka, Michio ^b   Kamaya, Hiroshi ^c   Kaneshina, Shoji ^a   Ueda, Issaku ^c  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Charged local anesthetic; Negative adsorption; Preferential partitioning; Surface tension; Surface adsorbed film; Uncharged local anesthetic

Indexed keywords

ADSORPTION; DISSOCIATION; HYDROCHLORIC ACID; HYDROPHOBICITY; MIXTURES; PH EFFECTS; SURFACE REACTIONS; SURFACE TENSION; THERMODYNAMICS;

LIDOCAINE (LC); MOLE FRACTION; PROTONATION; SURFACE ADSORBED FILMS;

ANESTHETICS;

HYDROCHLORIC ACID; LIDOCAINE; LOCAL ANESTHETIC AGENT;

ADSORPTION; AQUEOUS SOLUTION; ARTICLE; CELL MEMBRANE; CHEMICAL COMPOSITION; CONTROLLED STUDY; DENSITY; DISSOCIATION CONSTANT; DRUG STRUCTURE; HYDROPHOBICITY; MATHEMATICAL COMPUTING; PH; PRIORITY JOURNAL; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; SURFACE PROPERTY; SURFACE TENSION; THERMODYNAMICS; TRANSPORT KINETICS;

EID: 13144252238     PISSN: 0303402X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00396-004-1177-1     Document Type: Article

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