Identification of a potent, selective non-peptide CXCR2 antagonist that inhibits interleukin-8-induced neutrophil migration

Chemtracts

Volumn 12, Issue 1, 1999, Pages 57-60

  White, J R ^a   Lee, J M ^a   Young, P R ^a   Hertzberg, R P ^a   Jurewicz, A J ^a   Chaikin, M A ^a   Widdowson, K ^a   Foley, J J ^a   Martin, L D ^a   Griswold, D E ^a   Sarau, H M ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 BROMOPHENYL) 3 (2 HYDROXY 4 NITROPHENYL)UREA; 1,1' [1,4 PHENYLENE BIS(METHYLENE)] BIS 1,4,8,11 TETRA AZACYCLOTETRADECANE; ANTIINFLAMMATORY AGENT; BETA CHEMOKINE; CHEMOKINE RECEPTOR; INTERLEUKIN 8; LEUKOTRIENE B4; MONOCLONAL ANTIBODY; MONOCYTE CHEMOTACTIC PROTEIN 1; RANTES; RECEPTOR BLOCKING AGENT; RP 23618; SKF 83589; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; CALCIUM MOBILIZATION; CELL STRAIN HL 60; CHO CELL; DRUG SELECTIVITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; INFLAMMATORY DISEASE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NOTE;

EID: 13044258889     PISSN: 14319268     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (7)

1. For reviews on chemokines, see: (a) Ponath, P.D. Exp. Opin. Invest. Drugs 1998, 7, 1; (b) Luster, A.D. N. Engl. J. Med. 1998, 338(7), 436; (c) Baggiolini, M. Nature 1998, 392(9), 565.
2. For reviews on chemokines, see: (a) Ponath, P.D. Exp. Opin. Invest. Drugs 1998, 7, 1; (b) Luster, A.D. N. Engl. J. Med. 1998, 338(7), 436; (c) Baggiolini, M. Nature 1998, 392(9), 565.
3. For reviews on chemokines, see: (a) Ponath, P.D. Exp. Opin. Invest. Drugs 1998, 7, 1; (b) Luster, A.D. N. Engl. J. Med. 1998, 338(7), 436; (c) Baggiolini, M. Nature 1998, 392(9), 565.
4. Donzella, G.A., Schols, D., Lin, S.W., Este, J.A., Nagashima, K.A., Maddon, P.J., Allaway, G.P., Sakmar, T.P., Henson, G., De Clercq, E., Moore, J.P. Nat. Med. (N.Y.) 1998, 4(1), 72.
5. Bright, C., Brown, T.J., Cox, P., Halley, F., Lockey, P., Mclay, I.M., Moore, U., Porter, B., Williams, R.J. Bioorg. Med. Chem. Lett., 1998, 8(7), 771.
6. Horcher, M., Rot, A., Aschauer, H., Besemer, J. Cytokine 1998, 10(1). 1.
7. Baggiolini, M., Moser, B. J. Exp. Med. 1997, 186(8), 1189.