Kinetic study of early regenerative effects of RGTA11, a heparan sulfate mimetic, in rat craniotomy defects

Calcified Tissue International

Volumn 75, Issue 6, 2004, Pages 517-525

  Lafont, J ^a   Blanquaert, F ^b   Colombier, M L ^a   Barritault, D ^b   Carueelle, J P ^b   Saffar, J L ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b Université Paris 12 ^*  (France)

Author keywords

Bone repair; Dura mater; Osteoprogenitors; Provisional matrix; RGTA; Type III collagen; Vascularization

Indexed keywords

ALKALINE PHOSPHATASE BONE ISOENZYME; CARBOXYMETHYLBENZYLAMIDE SULFATE DEXTRAN; COLLAGEN; COLLAGEN TYPE 3; DEXTRAN DERIVATIVE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; HEPARAN SULFATE; UNCLASSIFIED DRUG;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE REMODELING; BONE STRUCTURE; CELL AGGREGATION; CELL COUNT; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; DURA MATER; MALE; NONHUMAN; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT; SKULL DEFECT; STEM CELL;

ANIMALS; BONE REGENERATION; CATTLE; CELLS, CULTURED; COLLAGEN; CRANIOTOMY; DEXTRANS; ENDOTHELIUM, VASCULAR; KINETICS; MALE; NEOVASCULARIZATION, PHYSIOLOGIC; RATS; RATS, WISTAR; SKULL; TIME FACTORS; WOUND HEALING;

EID: 12944308334     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-004-0012-5     Document Type: Article

References (34)

1. Hadjiargyrou M, et al. (2002) Transcriptional profiling of bone regeneration - insight into the molecular complexity of wound repair. J Biol Chem 277:30177-30182
2. Frost HM (1989) The biology of fracture healing. An overview of fracture healing. Part I. Clin Orthop 248:283-293
3. Marie PJ (1999) Cellular and molecular alterations of osteoblasts in human disorders of bone formation. Histol Histopathol 14:525-538
4. Gerstenfeld LC, et al. (2003) Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. J Cell Biochem 88:873-884
5. Zhang X, et al. (2002) Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair. J Clin Invest 109:1405-1415
6. Lafont J, et al. (1994) Derivatized dextrans (CMDBS) as promoters of bone healing. Factors influencing their effectiveness. Cells Mater 4:219-230
7. Blanquaert F, et al. (1995) Heparan-like molecules induce the repair of skull defects. Bone 17:499-506
8. Lafont J, et al. (1998) RGTA11, a new healing agent, triggers developmental events during healing of craniotomy defects in adult rats. Growth Factors 16:23-38
9. Escartin Q, et al. (2003) A new approach to treat tissue destruction in periodontitis with heparan mimetics. FASEB J 17:644-651
10. Meddahi A, et al. (1996) FGF protection and inhibition of human neutrophil elastase by carboxymethyl benzylamide sulfonate dextran derivatives. Int J Biol Macromol 18:141-145
11. Ledoux D, et al. (2000) Human plasmin enzymatic activity is inhibited by chemically modified dextrans. J Biol Chem 275:29383-29390
12. Ledoux D, et al. (2003) Heparin-like dextran derivatives as well as glycosaminoglycans inhibit the enzymatic activity of human cathepsin G. FEBS Lett 537:23-29
13. Morvan FO, et al. (2004) An engineered biopolymer prevents mucositis induced by 5-fluorouracil in hamsters. Am J Pathol 164:739-746
14. Tardieu M, et al. (1992) Derivatized dextrans mimic heparin as stabilizers, potentiators, and protectors of acidic or basic FGF. J Cell Physiol 150:194-203
15. Meddahi A, et al. (1996) Heparin-like polymers derived from dextran enhance colonie anastomosis resistance to leakage. J Biomed Mater Res 31:293-297
16. Desgranges P, et al. (1997) Transmural endothelialization of vascular prostheses is regulated in vitro by Fibroblast Growth Factor-2 and heparan-like molecule. Int J Artif Organs 20:589-598
17. Street J, et al. (2002) Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover. Proc Natl Acad Sci USA 99:9656-9661
18. Streeten EA, et al. (1989) Cloned endothelial cells from fetal bovine bone. Proc Natl Acad Sci USA 86:916-920
19. Page M, Hogg J, Ashhurst DE (1986) The effects of mechanical stability on the macromolecules of the connective tissue matrices produced during fracture healing. I. The collagens. Histochem J 18:251-265
20. Lane JM, et al. (1986) Immunofluorescent localization of structural collagen types in endochondral fracture repair. J Orthop Res 4:318-329
21. Opperman LA, et al. (1996) Dura mater secretes soluble heparin-binding factors required for cranial suture morphogenesis. In Vitro Cell Dev Biol-Animal 32:627-632
22. Opperman LA, et al. (1994) In the absence of periosteum, transplanted fetal and neonatal rat coronal sutures resist osseous obliteration. J Craniofac Surg 5:327-332
23. Winet H (1996) The role of microvasculature in normal and perturbed bone healing as revealed by intravital microscopy. Bone 19:S39-S57
24. Jones AR, Clark CC, Brighton CT (1995) Microvessel endothelial cells and pericytes increase proliferation and repress osteoblast phenotypic markers in rat calvarial bone cell cultures. J Orthop Res 13:553-561
25. Villars F, et al. (2000) Effect of human endothelial cells on human bone marrow stromal cell phenotype: role of VEGF? J Cell Biochem 79:672-685
26. Villars F, et al. (2002) Effect of HUVEC on human osteoprogenitor cell differentiation needs heterotypic gap junction communication. Am J Physiol Cell Physiol 282:C775-C785
27. Steinbrech DS, et al. (2000) VEGF expression in an osteoblast-like cell line is regulated by a hypoxia response mechanism. Am J Physiol Cell Physiol 278:C853-C860
28. Knighton DR, et al. (1983) Oxygen tension regulates the expression of angiogenesis factor by macrophages. Science 221:1283-1285
29. Crowther M, et al. (2001) Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors. J Leukocyte Biol 70:478-490
30. Levine JP, et al. (1998) Studies in cranial suture biology. Regional dura mater determines overlying suture biology. Plast Reconstr Surg 101:1441-1447
31. Greenwald JA, et al. (2000a) Regional differentiation of cranial suture-associated dura mater in vivo and in vitro: implications for suture fusion and patency. J Bone Miner Res 15:2413-2430
32. Greenwald JA, et al. (2000b) Biomolecular mechanisms of carvarial bone induction: immature versus mature dura mater. Plast Reconstr Surg 105:1382-1392
33. Streeten EA, Brandi ML (1990) Biology of bone endothelial cells. Bone Miner 10:85-94
34. Moscatelli D (1987) High and low affinity binding sites for basic fibroblast growth factor on cultured cells: absence of a role for low affinity binding in the stimulation of plasminogen activator production by bovine capillary endothelial cells. J Cell Physiol 131:123-130