Multimodality treatment including postoperative radiation and concurrent chemotherapy with weekly docetaxel is feasible and effective in patients with oral and oropharyngeal cancer

Strahlentherapie und Onkologie

Volumn 181, Issue 1, 2005, Pages 26-34

  Kovács, Adorján F ^a,b   Mose, Stephan ^a   Böttcher, Heinz D ^a   Bitter, Klaus ^a  

^a GOETHE UNIVERSITY   (Germany)

^b Uniklinik Haus 21   (Germany)

Author keywords

Adjuvant radiation; Docetaxel; Head and neck cancer; Multimodal treatment

Indexed keywords

CISPLATIN; DOCETAXEL; FENTANYL; MEPIVACAINE; SODIUM THIOSULFATE;

ACUTE TOXICITY; ADJUVANT CHEMOTHERAPY; ADULT; AGED; ANALGESIA; ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CHEMOTHERAPY; CHRONIC TOXICITY; DISEASE SEVERITY; DRUG TOLERABILITY; DRUG TOLERANCE; FEMALE; FOLLOW UP; HEAD AND NECK CANCER; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MOUTH CANCER; MUCOSA INFLAMMATION; MULTIMODALITY CANCER THERAPY; OROPHARYNX CANCER; SERODIAGNOSIS; SIDE EFFECT; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TIME SERIES ANALYSIS; TOOTH PAIN;

ADULT; AGED; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, SQUAMOUS CELL; CISPLATIN; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; HEAD; HEAD AND NECK NEOPLASMS; HUMANS; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRA-ARTERIAL; MALE; MIDDLE AGED; NECK; NECK DISSECTION; NEOADJUVANT THERAPY; NEOPLASM STAGING; POSTOPERATIVE CARE; RADIOTHERAPY DOSAGE; RADIOTHERAPY, ADJUVANT; SURVIVAL ANALYSIS; TAXOIDS; THIOSULFATES; TIME FACTORS; TREATMENT OUTCOME;

EID: 12944296616     PISSN: 01797158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00066-005-1272-3     Document Type: Article

References (45)

1. Adelstein DJ, Lavertu P, Saxton JP, et al. Mature results of a phase III randomized trial comparing concurrent chemoradiotherapy with radiation therapy alone in patients with stage III and IV squamous cell carcinoma of the head and neck. Cancer 2000;88:876-83.
2. Al-Sarraf M, Pajak TF, Byhardt RW, Beitler JJ, Salter MM, Cooper JS. Postoperative radiotherapy with concurrent cisplatin appears to improve locoregional control of advanced, resectable head and neck cancers: RTOG 88-24. Int J Radiat Oncol Biol Phys 1997;37:777-82.
3. Bachaud JM, David JM, Boussin G, Daly N. Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced squamous cell carcinoma of the head and neck: preliminary report of a randomized trial. Int J Radiat Oncol Biol Phys 1991;20:243-6.
4. Bachaud JM, Cohen-Jonathan E, Alzieu C, David JM, Serrano E, Daly-Schveitzer N. Combined postoperative radiotherapy and weekly cisplatin infusion for locally advanced head and neck carcinoma: final report of a randomized trial. Int J Radiat Oncol Biol Phys 1996;36:999-1004.
5. Bier J. Definitionen zum radikalchirurgischen Vorgehen bei Plattenepithelkarzinomen der Mundhöhle. Deutsch-Österreichisch- Schweizerischer Arbeitskreis für Tumoren im Kiefer- und Gesichtsbereich (DÖSAK). Dtsch Z Mund Kiefer Gesichtschir 1982;6:369-72.
6. Brizel DM, Albers ME, Fisher SR, et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998;338:1798-804.
7. Calais G, Alfonsi M, Bardet E, et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst 1999;91:2081-6.
8. Calais G, Bardet E, Sire C, et al. Radiotherapy with concomitant weekly docetaxel for stages III/IV oropharynx carcinoma. Results of the 98-02 GORTEC Phase II trial. Int J Radiat Oncol Biol Phys 2004;58:161-6.
9. Caponigro F, Massa E, Manzione L, et al. Docetaxel and cisplatin in locally advanced or metastatic squamous-cell carcinoma of the head and neck: a phase II study of the Southern Italy Cooperative Oncology Group (SICOG). Ann Oncol 2001;12:199-202.
10. Catimel G, Verweij J, Mattijssen V, et al. Docetaxel (Taxotere): an active drug for the treatment of patients with advanced squamous cell carcinoma of the head and neck. EORTC Early Clinical Trials Group. Ann Oncol 1994;5:533-7.
11. Deutsche Krebsgesellschaft (Hrsg). Kurzgefaßte Interdisziplinä re Leitlinien 2000/Koordination: Informationszentrum für Standards in der Onkologie (ISTO), B1 (Interdisziplinäre Kurzgefaßte Leitlinien der Deutschen Krebsgesellschaft und ihrer Arbeitsgemeinschaften, der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf-und Halschirurgie und der Deutschen Gesellschaft für Mund-, Kiefer- und Gesichtschirurgie). München: Zuckschwerdt, 2000:69-91.
12. Dreyfuss AI, Clark JR, Norris CM, et al. Docetaxel: an active drug for squamous cell carcinoma of the head and neck. J Clin Oncol 1996;14: 1672-8.
13. Hainsworth JD, Burris HA, Greco FA. Weekly administration of docetaxel (Taxotere): summary of clinical data. Semin Oncol 1999;26:19-24.
14. Hennequin C, Giocanti N, Favaudon V. Interaction of ionizing radiation with paclitaxel (Taxol) and docetaxel (Taxotere) in HeLa and SQ20B cells. Cancer Res 1996;56:1842-50.
15. Herscher LL, Hahn SM, Kroog G, et al. Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer. J Clin Oncol 1998;16:635-41.
16. Hesse K, Heinrich B, Zimmermann F, et al. Combined radiochemotherapy with docetaxel in patients with unresectable locally advanced head and neck tumors. Strahlenther Onkol 2000;176:67-72.
17. Howaldt HP, Kainz M, Euler B, Vorast H. Proposal for modification of the TNM staging classification for cancer of the oral cavity. DÖSAK. J Craniomaxillofac Surg 1999;27:275-88.
18. Janinis J, Papadakou M, Panagos G, et al. Sequential chemoradiotherapy with docetaxel, cisplatin, and 5-fluorouracil in patients with locally advanced head and neck cancer. Am J Clin Oncol 2001;24:227-31.
19. Jeremic B, Shibamoto Y, Milicic B, et al. Hyperfractionated radiation therapy with or without concurrent low-dose daily cisplatin in locally advanced squamous cell carcinoma of the head and neck: A prospective randomized trial. J Clin Oncol 2000;18:1458-64.
20. Kaplan E, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-81.
21. Koukourakis MI, Bizakis JG, Skoulakis CE, et al. Combined irinotecan, docetaxel and conventionally fractionated radiotherapy in locally advanced head and neck cancer. A phase I dose escalation study. Anticancer Res 1999;19:2305-9.
22. Kovács AF, Turowski B, Ghahremani TM, Loitz M. Intra-arterial chemotherapy as neoadjuvant treatment of oral cancer. J Craniomaxillofac Surg 1999; 27:302-7.
23. Kovács AF, Obitz P, Wagner M. Monocomponent chemoembolization in oral and oropharyngeal cancer using an aqueous crystal suspension of cisplatin. Br J Cancer 2002;86:196-202.
24. Kovács AF, Schiemann M, Turowski B. Combined modality treatment of oral and oropharyngeal cancer including neoadjuvant intraarterial cisplatin and radical surgery followed by concurrent radiation and chemotherapy with weekly docetaxel - three year results of a pilot study. J Craniomaxillofac Surg 2002;30:112-20.
25. Kuhnt T, Becker A, Pigorsch S, et al. Aggressive simultaneous radiochemotherapy with cisplatin and paclitaxel in combination with accelerated hyperfractionated radiotherapy in locally advanced head and neck tumors. Results of a phase I-II trial. Strahlenther Onkol 2003;179:673-81.
26. Mauer AM, Masters GA, Haraf DJ, et al. Phase I study of docetaxel with concomitant thoracic radiation therapy. J Clin Oncol 1998;16:159-64.
27. Miller AB, Hoogstraten B, Staquet M, Winkler A. Reporting results of cancer treatment. Cancer 1981;47:207-14.
28. Pignon JP, Bourhis J, Domenge C, Designe L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-analysis of chemotherapy on head and neck cancer. Lancet 2000; 355:949-55.
29. Posner MR, Colevas AD, Tishler RB. The role of induction chemotherapy in the curative treatment of squamous cell cancer of the head and neck. Semin Oncol 2000;27:13-24.
30. Pradier O, Rave-Frank M, Lehmann J, et al. Effects of docetaxelin combination with radiation on human head and neck cancer cells (ZMK-1) and cervical squamous cell carcinoma cells (CaSki). Int J Cancer 2001;91:840-5.
31. Robbins KT, Denys D, and the Committee for Neck Dissection Classification, American Head and Neck Society. The American Head and Neck society's revised classification for neck dissection. In: Johnson JT, Shaha AR, eds. Proc. of the 5th International Conference in Head and Neck Cancer. Madison: Omnipress, 2000:365-71.
32. Schmidberger H, Rave-Fränk M, Kim S, Hille A, Pradier O, Hess CF. Strahleninduzierte Mukositis und neutrophile Granulozyten in der Mundschleimhaut. Strahlenther Onkol 2003;179:667-72.
33. Schrijvers DL, Vroman P, Dyck J, et al. Weekly docetaxel in patients with recurrent and/or metastatic head and neck cancer. Proc Am Soc Clin Oncol 2001;20:198b.abstract 2544.
34. Seegenschmiedt MH. Interdisciplinary documentation of treatment side effects in oncology. Present status and perspectives. Strahlenther Onkol 1998;174:Suppl 3:S25-9.
35. Shah JP. Evidence-based therapy for oral cancer. World Congress on Medicine and Health, Hannover, Germany, 09.08.2000. Available from URL: www. mh-hannover.de/aktuelles/projekte/mmm/germanversion/d_index_mmm. html (abstract).
36. Sobin LH, Wittekind C, eds. UICC: TNM classification of malignant tumours. New York: John Wiley & Sons, Inc., 1997.
37. Staar S, Rudat V, Stützer H, et al. Intensified hyperfractionated accelerated radiotherapy limits the additional benefit of simultaneous chemotherapy - results of a multicentric randomized German trial in advanced head-and-neck cancer. Int J Radiat Oncol Biol Phys 2001;50:1161-71.
38. Sunwoo JB, Herscher LL, Kroog GS, et al. Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer. J Clin Oncol 2001;19:800-11.
39. Tishler RB, Schiff PB, Geard CR, Hall EJ. Taxol: a novel radiation sensitizer. Int J Radiat Oncol Biol Phys 1992;22:613-7.
40. Tishler RB, Norris CM Jr, Colevas AD, et al. A phase I/II trial of concurrent docetaxel and radiation after induction chemotherapy in patients with poor prognosis squamous cell carcinoma of the head and neck. Cancer 2002; 95:1472-81.
41. Tupchong L, Scott CB, Blitzer PH, et al. Randomized study of preoperative versus postoperative radiation therapy in advanced head and neck carcinoma: long-term follow-up of RTOG study 73-03. Int J Radiat Oncol Biol Phys 1991;20:21-8.
42. Vandenbrouck C, Sancho H, Le Fur R, Richard JM, Cachin Y. Results of a randomized clinical trial of preoperative irradiation versus postoperative in treatment of tumors of the hypopharynx. Cancer 1977;39:1445-9.
43. Varveris H, Delakas D, Anezinis P, et al. Concurrent platinum and docetaxel chemotherapy and external radical radiotherapy in patients with invasive transitional cell bladder carcinoma. A preliminary report of tolerance and local control. Anticancer Res 1997;17:4771-80.
44. Volling P, Schröder M. Vorläufige Ergebnisse einer prospektiv randomisierten Studie zur primären Chemotherapie bei Mundhöhlen- und Pharynxkarzinomen. HNO 1995;43:58-64.
45. Wiltfang J, Grabenbauer G, Bloch-Birkholz A, Leher A, Neukam FW, Kessler P. Beurteilung der Lebensqualität von Patienten mit Plattenepithelkarzinomen der Mundhöhle. Vergleich von zwei Behandlungsstrategien in einer prospektiven Studie - erste Ergebnisse. Strahlenther Onkol 2003;179: 682-9.