The FK506 binding protein 13 kDa (FKBP13) interacts with the C-chain of complement C1q

BMC Pharmacology

Volumn 4, Issue , 2004, Pages

  Neye, Holger ^a   Verspohl, Eugen J ^b  

^a KV Niedersachsen   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT COMPONENT C1Q; CYCLOPHILIN A; FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 12; FK 506 BINDING PROTEIN 13; FK 506 BINDING PROTEIN 25; FK 506 BINDING PROTEIN 52; IMMUNOPHILIN; TACROLIMUS; UNCLASSIFIED DRUG; FKBP 13; FKBP-13; HYBRID PROTEIN; PEPTIDE FRAGMENT;

ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG STRUCTURE; FETUS; FETUS LIVER; GENE EXPRESSION; GENE LIBRARY; GENETIC COMPLEMENTATION; GENETIC SCREENING; MOLECULAR SIZE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; REACTION ANALYSIS; TWO HYBRID SYSTEM; YEAST; ANIMAL; DRUG EFFECT; HUMAN; IMMUNOLOGY; METABOLISM; RAT; SACCHAROMYCES CEREVISIAE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; COMPLEMENT C1Q; CYCLOPHILIN A; GENE LIBRARY; HUMANS; PEPTIDE FRAGMENTS; PROTEIN BINDING; RATS; RECOMBINANT FUSION PROTEINS; SACCHAROMYCES CEREVISIAE; TACROLIMUS; TACROLIMUS BINDING PROTEINS;

EID: 12944266754     PISSN: 14712210     EISSN: None     Source Type: Journal    
DOI: 10.1186/1471-2210-4-19     Document Type: Article

References (25)

1. Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL: Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry 1992, 31: 896-3901.
2. Jayaraman T, Brillantes A, Timerman AP, Fleischer S, Erdjument-Bromage H, Tempst P, Marks AR: FK506 binding protein associated with the calcium release channel (ryanodine receptor). J Biol Chem 1992, 267:9474-9477.
3. Timerman AP, Onoue H, Xin HB, Barg S, Copello J, Wiederrecht G, Fleischer S: Selective binding of FKBP12.6 by the cardiac ryanodine receptor. J Biol Chem 1996, 271:20385-91.
4. Peattie DA, Harding MW, Fleming MA, DeCenzo MT, Lippke JA, Livingston DJ, Benasutti M: Expression and Characterization of Human FKBP52, an Immunophilin That Associates With The 90-kDa Heat Shock Protein and is a Component of the Steroid Receptor Complexes. Proc Natl Acad Sci USA 1992, 89:10974-10978.
5. Nigam SK, Jin YJ, Jin MJ, Bush KT, Bierer BE, Burakoff SJ: Localization of the FK506-binding protein, FKBP 13, to the lumen of the endoplasmic reticulum. Biochem J 1993, 294:511-515.
6. Walensky LD, Gascard P, Fields ME, Blackshaw S, Conboy JG, Mohandas N, Snyder SH: The 13-kD FK506 binding protein, FKBP13, interacts with a novel homologue of the erythrocyte membrane cytoskeletal protein 4.1. J Cell Biol 1998, 141:143-153.
7. Chambraud B, Radanyi C, Camonis JH, Shazand K, Rajkowski K, Baulieu EE: FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin. J Biol Chem 1996, 271: 2923-32929.
8. Jin YJ, Burakoff SJ: The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin. Proc Natl Acad Sci U S A 1993, 90:7769-73.
9. Yang WM, Yao YL, Seto E: The FK506-binding protein 25 functionally associates with histone deacetylases and with transcription factor YY1. Embo J 2001, 20:4814-25.
10. Sellar GC, Blake DJ, Reid KB: Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q. Biochem J 1991, 274:481-90.
11. Navratil JS, Korb LC, Ahearn JM: Systemic lupus erythematosus and complement deficiency: clues to a novel role for the classical complement pathway in the maintenance of immune tolerance. Immunopharmacology 1999, 42:47-52.
12. Botto M, Dell'Agnola C, Bygrave AE, Thompson EM, Cook HT, Petry F, Loos M, Pandolfi PP, Walport MJ: Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998, 19:56-9.
13. McGreal EP, Ikewaki N, Akatsu H, Morgan BP, Gasque P: Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q. J Immunol 2002, 168:5222-32.
14. Petrenko O, Beavis A, Klaine M, Kittappa R, Godin I, Lemischka IR: The molecular characterization of the fetal stem cell marker AA4. Immunity 1999, 10:691-700.
15. Klickstein LB, Barbashov SF, Liu T, Jack RM, Nicholson-Weller A: Complement receptor type 1 (CR1, CD35) is a receptor for C1q. Immunity 1997, 7:345-55.
16. Malhotra R, Willis AC, Jensenius JC, Jackson J, Sim RB: Structure and homology of human C1q receptor (collectin receptor). Immunology 1993, 78:341-8.
17. Ghebrehiwet B, Lim BL, Peerschke EI, Willis AC, Reid KB: Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q. J Exp Med 1994, 179:1809-21.
18. Feldkämper I, Verspohl EJ, Neye H: The serpins alpha-1-antitrypsin and alpha-1-antichymotrypsin specifically interact with immunophilins. Pharmazie 2003, 58:811-816.
19. Clardy J: The chemistry of signal transduction. Proc Natl Acad Sci U S A 1995, 92:56-61.
20. Bartel PL, Chien C-T, Sternglanz R, Fields S: Using the two-hybrid system to detect protein-protein interactions. In: Cellular Interactions in Development: A Practical Approach Edited by: Hartley DA. Oxford: Oxford Univ Press; 1993:153-179.
21. Galarneau A, Primeau M, Trudeau LE, Michnick SW: Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions. Nat Biotechnol 2002, 20:619-22.
22. Sideraki V, Huang W, Palzkill T, Gilbert HF: A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfolding and aggregation. Proc Natl Acad Sci U S A 2001, 98:283-8.
23. Gietz D, S Jean A, Woods RA, Schiestl RH: Improved method for high efficiency transformation of intact yeast cells. Nucleic Acids Res 1992, 20:1425.
24. Kaiser C, Michaelis S, Mitchell A: Methods in Yeast Genetics: A Cold Spring Harbor Laboratory Course Manual Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press; 1994.
25. Asfari M, Janjic D, Meda P, Li G, Halban PA, Wollheim CB: Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 1992, 130: 67-78.